Recent news

Paper on GO-annotating key players in Parkinson's Disease published in Neuroinformatics

Read more about how we at UCL are using GO to annotate key players in Parkinson's disease. Our latest publication has just been published in Neuroinformatics: http://www.ncbi.nlm.nih.gov/pubmed/26825309.

Cardiovascular Gene Annotation Newsletter February 2016

The UCL cardiovascular gene annotation newsletter is now available at http://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslette... A new biocurator joins us this year, Barbara Czub, and we will be supervising 2 MSc student projects. In addition, Jess and Nancy have been annotating the telomere maintenance.

Connecting together multiple GO annotations: a report on the LEGO jamboree

In December, a group of us gathered at the Swiss Institute for Bioinformatics in Geneva to beta test and develop curation guidelines for a new GO annotation tool called Noctua. Noctua advances on the current GO annotation paradigm by allowing curators to connect together multiple annotations to give a cohesive picture of a biological process or mechanism.

To illustrate, consider the following two annotations which follow the current datamodel, which associates genes with GO terms:
  • TEM1 enables GTPase activity

Parkinson's Gene Annotation Project Newsletter, January 2016

The latest UCL Parkinson's UK gene annotation newsletter is now available at https://www.ucl.ac.uk/functional-gene-annotation/neurological/newsletter.... Rebecca has been annotating the role of Wnt-signalling in dopaminergic neuron development, and Paul has been focusing on autophagy. The Parkinson’s UK Gene Ontology Initiative represents a collaboration between University College London and the European Bioinformatics Institute (EBI) and is supported by Parkinson's UK grant G-1307.

Cardiovascular Gene Annotation Newsletter November 2015

The UCL cardiovascular gene annotation newsletter is now available at http://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslette.... We have a new biocurator, Jess Buxton, a new look to our website, and our 2 MSc students have created 600 annotations between them. #UCLgene #UCL

Take the Gene Ontology Survey!

Survey Closed

The GO survey is now closed! You can still give us feedback on how we're doing or send us a note on twitter (@news4go).

Please assist the Gene Ontology (GO) project by completing a brief survey. The results will help us determine how we can make GO a better tool for your work, and will be used in preparation of our grant renewal. Completed surveys will be eligible for a prize draw.

Parkinson's Gene Annotation Project Newsletter October 2015

The UCL Parkinson's UK gene annotation newsletter is now available at https://www.ucl.ac.uk/functional-gene-annotation/neurological/newsletter... . Rebecca has been annotating proteins involved in WNT-signalling and Paul has been focusing on autophagy. The Parkinson’s UK Gene Ontology Initiative represents a collaboration between University College London and the European Bioinformatics Institute (EBI) and is supported by Parkinson's UK grant G-1307.

Minor change in formatting of Gene Association Files (GAF)

We have extended the With/From column (Column 8) of the GAF2 to allow the use of commas as delimiters as well as pipes ("|"). Any GAF files that include this should have "gaf-version: 2.1" in the header, this format is documented here: http://geneontology.org/page/go-annotation-file-gaf-format-21 Other than this there are no other changes.

Cardiovascular Gene Annotation Newsletter August 2015

The new UCL cardiovascular gene annotation newsletter http://www.ucl.ac.uk/functional-gene-annotation/cardiovascular/newslette... is now available. Nancy has been submitting annotating protein complexes, Rachael has finished writing the GOC microRNA annotation guidelines and Tony has created a new PSICQUIC dataset for inclusion in Cytoscape.

BHF funded UCL-EBI collaboration leads to improved network analysis

10% increase in human PPIs at PSICQUIC following UCL-EBI collaboration funded by BHF creates GOC PPI dataset http://tinyurl.com/ob5vldo