]> ORTHOMCL17408 GO:0003674 molecular_function ORTHOMCL17408 GO:0005488 binding GO:0003674->GO:0005488 GO:0005575 cellular_component ORTHOMCL17408 GO:0044464 cell part GO:0005575->GO:0044464 GO:0005623 cell GO:0005575->GO:0005623 GO:0008150 biological_process ORTHOMCL17408 GO:0050789 regulation of biological process GO:0008150->GO:0050789 GO:0065007 biological regulation GO:0008150->GO:0065007 GO:0008152 metabolic process GO:0008150->GO:0008152 GO:0048518 positive regulation of biological process GO:0008150->GO:0048518 GO:0009987 cellular process GO:0008150->GO:0009987 GO:0040007 growth GO:0008150->GO:0040007 GO:0048519 negative regulation of biological process GO:0008150->GO:0048519 GO:0040011 locomotion GO:0008150->GO:0040011 GO:0051179 localization GO:0008150->GO:0051179 GO:0032501 multicellular organismal process GO:0008150->GO:0032501 GO:0032502 developmental process GO:0008150->GO:0032502 GO:0045941 positive regulation of transcription Human Rat: ISS_only GO:0030018 Z disc Human Rat: ISS_only GO:0030308 negative regulation of cell growth Human Rat: ISS_only GO:0010596 negative regulation of endothelial cell migration Human Rat: ISS_only GO:0010613 positive regulation of cardiac muscle hypertrophy Human Rat GO:0060045 positive regulation of cardiac muscle cell proliferation Rat: ISS_only Chicken: ISS_only Mouse GO:0055015 ventricular cardiac muscle cell development Rat: ISS_only Chicken: ISS_only Mouse GO:0030509 BMP signaling pathway Human Rat: ISS_only GO:0033612 receptor serine/threonine kinase binding Human Rat: ISS_only GO:0055009 atrial cardiac muscle morphogenesis Rat: ISS_only Chicken Mouse GO:0005515 protein binding Human Rat: ISS_only GO:0005102 receptor binding GO:0005515->GO:0005102 GO:0055010 ventricular cardiac muscle morphogenesis Rat: ISS_only Chicken Mouse GO:0007507 heart development Rat: ISS_only Mouse GO:0007512 adult heart development Rat: ISS_only Chicken: ISS_only Mouse GO:0007507->GO:0007512 GO:0060038 cardiac muscle cell proliferation GO:0007507->GO:0060038 GO:0035051 cardiac cell differentiation GO:0007507->GO:0035051 GO:0003007 heart morphogenesis GO:0007507->GO:0003007 GO:0010614 negative regulation of cardiac muscle hypertrophy Rat: ISS_only Mouse GO:0007219 Notch signaling pathway Rat: ISS_only Chicken: ISS_only Mouse GO:0009986 cell surface Human Rat: ISS_only GO:0045214 sarcomere organization Human: ISS_only Rat GO:0032924 activin receptor signaling pathway Human Rat: ISS_only GO:0060347 heart trabecula formation Human: ISS_only Mouse GO:0010557 positive regulation of macromolecule biosynthetic process GO:0010557->GO:0045941 GO:0009891 positive regulation of biosynthetic process GO:0009891->GO:0010557 GO:0031328 positive regulation of cellular biosynthetic process GO:0009891->GO:0031328 GO:0009889 regulation of biosynthetic process GO:0009889->GO:0009891 GO:0010556 regulation of macromolecule biosynthetic process GO:0009889->GO:0010556 GO:0031326 regulation of cellular biosynthetic process GO:0009889->GO:0031326 GO:0019222 regulation of metabolic process GO:0019222->GO:0009889 GO:0009893 positive regulation of metabolic process GO:0019222->GO:0009893 GO:0060255 regulation of macromolecule metabolic process GO:0019222->GO:0060255 GO:0031323 regulation of cellular metabolic process GO:0019222->GO:0031323 GO:0050789->GO:0019222 GO:0050789->GO:0048518 GO:0050794 regulation of cellular process GO:0050789->GO:0050794 GO:0040008 regulation of growth GO:0050789->GO:0040008 GO:0050789->GO:0048519 GO:0040012 regulation of locomotion GO:0050789->GO:0040012 GO:0032879 regulation of localization GO:0050789->GO:0032879 GO:0051239 regulation of multicellular organismal process GO:0050789->GO:0051239 GO:0050793 regulation of developmental process GO:0050789->GO:0050793 GO:0065007->GO:0050789 GO:0065008 regulation of biological quality GO:0065007->GO:0065008 GO:0008152->GO:0019222 GO:0009058 biosynthetic process GO:0008152->GO:0009058 GO:0008152->GO:0009893 GO:0043170 macromolecule metabolic process GO:0008152->GO:0043170 GO:0044237 cellular metabolic process GO:0008152->GO:0044237 GO:0044238 primary metabolic process GO:0008152->GO:0044238 GO:0009058->GO:0009891 GO:0009058->GO:0009889 GO:0009059 macromolecule biosynthetic process GO:0009058->GO:0009059 GO:0044249 cellular biosynthetic process GO:0009058->GO:0044249 GO:0009893->GO:0009891 GO:0010604 positive regulation of macromolecule metabolic process GO:0009893->GO:0010604 GO:0031325 positive regulation of cellular metabolic process GO:0009893->GO:0031325 GO:0048518->GO:0009893 GO:0048522 positive regulation of cellular process GO:0048518->GO:0048522 GO:0051240 positive regulation of multicellular organismal process GO:0048518->GO:0051240 GO:0051094 positive regulation of developmental process GO:0048518->GO:0051094 GO:0010556->GO:0010557 GO:0045449 regulation of transcription GO:0010556->GO:0045449 GO:0060255->GO:0010556 GO:0060255->GO:0010604 GO:0010468 regulation of gene expression GO:0060255->GO:0010468 GO:0043170->GO:0060255 GO:0043170->GO:0009059 GO:0043170->GO:0010604 GO:0010467 gene expression GO:0043170->GO:0010467 GO:0044260 cellular macromolecule metabolic process GO:0043170->GO:0044260 GO:0043283 biopolymer metabolic process GO:0043170->GO:0043283 GO:0009059->GO:0010557 GO:0009059->GO:0010556 GO:0034645 cellular macromolecule biosynthetic process GO:0009059->GO:0034645 GO:0043284 biopolymer biosynthetic process GO:0009059->GO:0043284 GO:0010604->GO:0010557 GO:0010628 positive regulation of gene expression GO:0010604->GO:0010628 GO:0010628->GO:0045941 GO:0010468->GO:0010628 GO:0010468->GO:0045449 GO:0010467->GO:0010628 GO:0010467->GO:0010468 GO:0006350 transcription GO:0010467->GO:0006350 GO:0031328->GO:0045941 GO:0031325->GO:0031328 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GO:0031325->GO:0045935 GO:0031323->GO:0031325 GO:0031323->GO:0031326 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GO:0031323->GO:0019219 GO:0050794->GO:0031323 GO:0050794->GO:0048522 GO:0001558 regulation of cell growth GO:0050794->GO:0001558 GO:0048523 negative regulation of cellular process GO:0050794->GO:0048523 GO:0051270 regulation of cell motion GO:0050794->GO:0051270 GO:0042127 regulation of cell proliferation GO:0050794->GO:0042127 GO:0007165 signal transduction GO:0050794->GO:0007165 GO:0009987->GO:0050794 GO:0009987->GO:0044237 GO:0009987->GO:0048522 GO:0016049 cell growth GO:0009987->GO:0016049 GO:0009987->GO:0048523 GO:0006928 cell motion GO:0009987->GO:0006928 GO:0008283 cell proliferation GO:0009987->GO:0008283 GO:0048468 cell development GO:0009987->GO:0048468 GO:0048869 cellular developmental process GO:0009987->GO:0048869 GO:0007154 cell communication GO:0009987->GO:0007154 GO:0030029 actin filament-based process GO:0009987->GO:0030029 GO:0016043 cellular component organization GO:0009987->GO:0016043 GO:0044237->GO:0031325 GO:0044237->GO:0031323 GO:0044237->GO:0044249 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process GO:0044237->GO:0006139 GO:0044237->GO:0044260 GO:0048522->GO:0031325 GO:0008284 positive regulation of cell proliferation GO:0048522->GO:0008284 GO:0031326->GO:0031328 GO:0031326->GO:0045449 GO:0044249->GO:0031328 GO:0044249->GO:0031326 GO:0044249->GO:0034645 GO:0045449->GO:0045941 GO:0019219->GO:0045449 GO:0019219->GO:0045935 GO:0006139->GO:0019219 GO:0006139->GO:0006350 GO:0006139->GO:0045935 GO:0044238->GO:0006139 GO:0006350->GO:0045941 GO:0006350->GO:0045449 GO:0034961 cellular biopolymer biosynthetic process GO:0034961->GO:0006350 GO:0034645->GO:0034961 GO:0044260->GO:0034645 GO:0034960 cellular biopolymer metabolic process GO:0044260->GO:0034960 GO:0034960->GO:0034961 GO:0043283->GO:0034960 GO:0043283->GO:0043284 GO:0043284->GO:0034961 GO:0045935->GO:0045941 GO:0044449 contractile fiber part GO:0044449->GO:0030018 GO:0031674 I band GO:0044449->GO:0031674 GO:0030017 sarcomere GO:0044449->GO:0030017 GO:0044444 cytoplasmic part GO:0044444->GO:0044449 GO:0043292 contractile fiber GO:0044444->GO:0043292 GO:0044424 intracellular part GO:0044424->GO:0044444 GO:0005737 cytoplasm GO:0044424->GO:0005737 GO:0044464->GO:0009986 GO:0044464->GO:0044424 GO:0005622 intracellular GO:0044464->GO:0005622 GO:0005623->GO:0044464 GO:0005622->GO:0044424 GO:0005737->GO:0044444 GO:0043292->GO:0044449 GO:0030016 myofibril GO:0043292->GO:0030016 GO:0031674->GO:0030018 GO:0030017->GO:0031674 GO:0030016->GO:0030017 GO:0001558->GO:0030308 GO:0040008->GO:0001558 GO:0045926 negative regulation of growth GO:0040008->GO:0045926 GO:0040007->GO:0040008 GO:0040007->GO:0016049 GO:0040007->GO:0045926 GO:0016049->GO:0030308 GO:0016049->GO:0001558 GO:0008361 regulation of cell size GO:0008361->GO:0016049 GO:0045792 negative regulation of cell size GO:0008361->GO:0045792 GO:0065008->GO:0008361 GO:0045926->GO:0030308 GO:0048519->GO:0045926 GO:0048519->GO:0048523 GO:0051241 negative regulation of multicellular organismal process GO:0048519->GO:0051241 GO:0048523->GO:0030308 GO:0051271 negative regulation of cell motion GO:0048523->GO:0051271 GO:0045792->GO:0030308 GO:0010594 regulation of endothelial cell migration GO:0010594->GO:0010596 GO:0030334 regulation of cell migration GO:0030334->GO:0010594 GO:0030336 negative regulation of cell migration GO:0030334->GO:0030336 GO:0040012->GO:0030334 GO:0040011->GO:0040012 GO:0048870 cell motility GO:0040011->GO:0048870 GO:0051270->GO:0030334 GO:0051270->GO:0051271 GO:0032879->GO:0051270 GO:0051179->GO:0032879 GO:0051674 localization of cell GO:0051179->GO:0051674 GO:0006928->GO:0051270 GO:0006928->GO:0048870 GO:0006928->GO:0051271 GO:0051674->GO:0006928 GO:0016477 cell migration GO:0016477->GO:0030334 GO:0043542 endothelial cell migration GO:0016477->GO:0043542 GO:0016477->GO:0030336 GO:0048870->GO:0016477 GO:0043542->GO:0010596 GO:0043542->GO:0010594 GO:0030336->GO:0010596 GO:0051271->GO:0030336 GO:0010611 regulation of cardiac muscle hypertrophy GO:0010611->GO:0010613 GO:0010611->GO:0010614 GO:0010612 regulation of cardiac muscle adaptation GO:0010612->GO:0010611 GO:0010615 positive regulation of cardiac muscle adaptation GO:0010612->GO:0010615 GO:0010616 negative regulation of cardiac muscle adaptation GO:0010612->GO:0010616 GO:0043502 regulation of muscle adaptation GO:0043502->GO:0010612 GO:0014743 regulation of muscle hypertrophy GO:0043502->GO:0014743 GO:0014744 positive regulation of muscle adaptation GO:0043502->GO:0014744 GO:0014745 negative regulation of muscle adaptation GO:0043502->GO:0014745 GO:0051239->GO:0043502 GO:0051239->GO:0051240 GO:0060043 regulation of cardiac muscle cell proliferation GO:0051239->GO:0060043 GO:0051239->GO:0051241 GO:0032501->GO:0051239 GO:0003008 system process GO:0032501->GO:0003008 GO:0032501->GO:0051240 GO:0007275 multicellular organismal development GO:0032501->GO:0007275 GO:0032501->GO:0051241 GO:0043500 muscle adaptation GO:0043500->GO:0043502 GO:0014888 striated muscle adaptation GO:0043500->GO:0014888 GO:0014896 muscle hypertrophy GO:0043500->GO:0014896 GO:0043500->GO:0014744 GO:0043500->GO:0014745 GO:0003012 muscle system process GO:0003012->GO:0043500 GO:0003008->GO:0003012 GO:0014887 cardiac muscle adaptation GO:0014887->GO:0010612 GO:0014898 cardiac muscle hypertrophy GO:0014887->GO:0014898 GO:0014887->GO:0010615 GO:0014887->GO:0010616 GO:0014888->GO:0014887 GO:0014897 striated muscle hypertrophy GO:0014888->GO:0014897 GO:0014743->GO:0010611 GO:0014742 positive regulation of muscle hypertrophy GO:0014743->GO:0014742 GO:0014741 negative regulation of muscle hypertrophy GO:0014743->GO:0014741 GO:0014896->GO:0014743 GO:0014896->GO:0014897 GO:0014896->GO:0014742 GO:0014896->GO:0014741 GO:0014898->GO:0010613 GO:0014898->GO:0010614 GO:0014898->GO:0010611 GO:0014897->GO:0014898 GO:0010615->GO:0010613 GO:0014744->GO:0010615 GO:0014744->GO:0014742 GO:0051240->GO:0060045 GO:0051240->GO:0014744 GO:0014742->GO:0010613 GO:0008284->GO:0060045 GO:0042127->GO:0008284 GO:0042127->GO:0060043 GO:0008283->GO:0008284 GO:0008283->GO:0042127 GO:0033002 muscle cell proliferation GO:0008283->GO:0033002 GO:0051094->GO:0060045 GO:0050793->GO:0051094 GO:0050793->GO:0060043 GO:0032502->GO:0051094 GO:0032502->GO:0050793 GO:0048856 anatomical structure development GO:0032502->GO:0048856 GO:0032502->GO:0007275 GO:0032502->GO:0048869 GO:0009653 anatomical structure morphogenesis GO:0032502->GO:0009653 GO:0048646 anatomical structure formation GO:0032502->GO:0048646 GO:0060043->GO:0060045 GO:0060038->GO:0060045 GO:0060038->GO:0060043 GO:0014855 striated muscle cell proliferation GO:0014855->GO:0060038 GO:0033002->GO:0014855 GO:0048513 organ development GO:0048513->GO:0007507 GO:0007517 muscle development GO:0048513->GO:0007517 GO:0009887 organ morphogenesis GO:0048513->GO:0009887 GO:0048856->GO:0048513 GO:0048731 system development GO:0048856->GO:0048731 GO:0048856->GO:0009653 GO:0048731->GO:0048513 GO:0007275->GO:0048731 GO:0055013 cardiac muscle cell development GO:0055013->GO:0055015 GO:0055001 muscle cell development GO:0055001->GO:0055013 GO:0055002 striated muscle cell development GO:0055001->GO:0055002 GO:0048468->GO:0055001 GO:0030154 cell differentiation GO:0030154->GO:0048468 GO:0042692 muscle cell differentiation GO:0030154->GO:0042692 GO:0030154->GO:0035051 GO:0048869->GO:0030154 GO:0042692->GO:0055001 GO:0051146 striated muscle cell differentiation GO:0042692->GO:0051146 GO:0055012 ventricular cardiac muscle cell differentiation GO:0055012->GO:0055015 GO:0055007 cardiac muscle cell differentiation GO:0055007->GO:0055012 GO:0035051->GO:0055007 GO:0051146->GO:0055007 GO:0051146->GO:0055002 GO:0014706 striated muscle development GO:0014706->GO:0051146 GO:0007517->GO:0014706 GO:0048644 muscle morphogenesis GO:0007517->GO:0048644 GO:0007179 transforming growth factor beta receptor signaling pathway GO:0007179->GO:0030509 GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway GO:0007178->GO:0032924 GO:0007178->GO:0007179 GO:0007167 enzyme linked receptor protein signaling pathway GO:0007167->GO:0007178 GO:0007166 cell surface receptor linked signal transduction GO:0007166->GO:0007219 GO:0007166->GO:0007167 GO:0007165->GO:0007166 GO:0007154->GO:0007165 GO:0005102->GO:0033612 GO:0005488->GO:0005515 GO:0055008 cardiac muscle morphogenesis GO:0055008->GO:0055009 GO:0055008->GO:0055010 GO:0048644->GO:0055008 GO:0009887->GO:0048644 GO:0009887->GO:0003007 GO:0060343 trabecula formation GO:0009887->GO:0060343 GO:0009653->GO:0009887 GO:0009653->GO:0048646 GO:0003007->GO:0060347 GO:0003007->GO:0055008 GO:0010616->GO:0010614 GO:0014745->GO:0010616 GO:0014745->GO:0014741 GO:0051241->GO:0014745 GO:0014741->GO:0010614 GO:0031032 actomyosin structure organization GO:0031032->GO:0045214 GO:0030239 myofibril assembly GO:0031032->GO:0030239 GO:0030036 actin cytoskeleton organization GO:0030036->GO:0031032 GO:0030029->GO:0030036 GO:0030239->GO:0045214 GO:0022607 cellular component assembly GO:0022607->GO:0030239 GO:0016043->GO:0022607 GO:0055002->GO:0030239 GO:0060343->GO:0060347 GO:0048646->GO:0060343