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<g id="edge53" class="edge"><title>GO:0042221&#45;&gt;GO:0010033</title>
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<g id="edge85" class="edge"><title>GO:0042221&#45;&gt;GO:0010035</title>
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<text text-anchor="middle" x="2999" y="-317.667" style="font-family:Arial;font-size:10px;">fructose 1,6&#45;bisphosphate</text>
<text text-anchor="middle" x="2999" y="-305.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<text text-anchor="middle" x="2999" y="-287.667" style="font-family:Arial;font-size:10px;">Human</text>
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<polygon style="fill:none;stroke:black;" points="2940,-266 2940,-282 3058,-282 3058,-266 2940,-266"/>
<text text-anchor="middle" x="2999" y="-271.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0005634 -->
<g id="node16" class="node"><title>GO:0005634</title>
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<polygon style="fill:none;stroke:black;" points="844,-386 844,-402 884,-402 884,-386 844,-386"/>
<text text-anchor="middle" x="864" y="-391.667" style="font-family:Arial;font-size:10px;">nucleus</text>
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<polygon style="fill:none;stroke:black;" points="844,-370 844,-386 884,-386 884,-370 844,-370"/>
<text text-anchor="middle" x="864" y="-375.667" style="font-family:Arial;font-size:10px;">Human</text>
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<polygon style="fill:none;stroke:black;" points="844,-354 844,-370 884,-370 884,-354 844,-354"/>
<text text-anchor="middle" x="864" y="-359.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0042594 -->
<g id="node17" class="node"><title>GO:0042594</title>
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<polygon style="fill:none;stroke:black;" points="1186,-522 1186,-564 1244,-564 1244,-522 1186,-522"/>
<text text-anchor="middle" x="1215" y="-553.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1215" y="-541.667" style="font-family:Arial;font-size:10px;">starvation</text>
<text text-anchor="middle" x="1215" y="-529.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0006116 -->
<g id="node18" class="node"><title>GO:0006116</title>
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<polygon style="fill:none;stroke:black;" points="2351,-36 2351,-52 2427,-52 2427,-36 2351,-36"/>
<text text-anchor="middle" x="2389" y="-41.6667" style="font-family:Arial;font-size:10px;">NADH oxidation</text>
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<polygon style="fill:none;stroke:black;" points="2351,-20 2351,-36 2427,-36 2427,-20 2351,-20"/>
<text text-anchor="middle" x="2389" y="-25.6667" style="font-family:Arial;font-size:10px;">Human</text>
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<polygon style="fill:none;stroke:black;" points="2351,-4 2351,-20 2427,-20 2427,-4 2351,-4"/>
<text text-anchor="middle" x="2389" y="-9.66667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0005829 -->
<g id="node19" class="node"><title>GO:0005829</title>
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<polygon style="fill:none;stroke:black;" points="584,-363 584,-393 622,-393 622,-363 584,-363"/>
<text text-anchor="middle" x="603" y="-382.667" style="font-family:Arial;font-size:10px;">cytosol</text>
<text text-anchor="middle" x="603" y="-370.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0010043 -->
<g id="node20" class="node"><title>GO:0010043</title>
<polygon style="fill:gold;stroke:gold;" points="1542,-522 1542,-564 1600,-564 1600,-522 1542,-522"/>
<polygon style="fill:none;stroke:black;" points="1542,-522 1542,-564 1600,-564 1600,-522 1542,-522"/>
<text text-anchor="middle" x="1571" y="-553.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1571" y="-541.667" style="font-family:Arial;font-size:10px;">zinc ion</text>
<text text-anchor="middle" x="1571" y="-529.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0051384 -->
<g id="node21" class="node"><title>GO:0051384</title>
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<polygon style="fill:none;stroke:black;" points="1433,-432 1433,-486 1499,-486 1499,-432 1433,-432"/>
<text text-anchor="middle" x="1466" y="-475.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1466" y="-463.667" style="font-family:Arial;font-size:10px;">glucocorticoid</text>
<text text-anchor="middle" x="1466" y="-451.667" style="font-family:Arial;font-size:10px;">stimulus</text>
<text text-anchor="middle" x="1466" y="-439.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0070061 -->
<g id="node22" class="node"><title>GO:0070061</title>
<polygon style="fill:white;stroke:white;" points="322,-551 322,-567 396,-567 396,-551 322,-551"/>
<polygon style="fill:none;stroke:black;" points="322,-551 322,-567 396,-567 396,-551 322,-551"/>
<text text-anchor="middle" x="359" y="-556.667" style="font-family:Arial;font-size:10px;">fructose binding</text>
<polygon style="fill:tomato;stroke:tomato;" points="322,-535 322,-551 396,-551 396,-535 322,-535"/>
<polygon style="fill:none;stroke:black;" points="322,-535 322,-551 396,-551 396,-535 322,-535"/>
<text text-anchor="middle" x="359" y="-540.667" style="font-family:Arial;font-size:10px;">Human</text>
<polygon style="fill:gold;stroke:gold;" points="322,-519 322,-535 396,-535 396,-519 322,-519"/>
<polygon style="fill:none;stroke:black;" points="322,-519 322,-535 396,-535 396,-519 322,-519"/>
<text text-anchor="middle" x="359" y="-524.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0043434 -->
<g id="node23" class="node"><title>GO:0043434</title>
<polygon style="fill:gold;stroke:gold;" points="1316,-602 1316,-656 1394,-656 1394,-602 1316,-602"/>
<polygon style="fill:none;stroke:black;" points="1316,-602 1316,-656 1394,-656 1394,-602 1316,-602"/>
<text text-anchor="middle" x="1355" y="-645.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1355" y="-633.667" style="font-family:Arial;font-size:10px;">peptide hormone</text>
<text text-anchor="middle" x="1355" y="-621.667" style="font-family:Arial;font-size:10px;">stimulus</text>
<text text-anchor="middle" x="1355" y="-609.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0005815 -->
<g id="node24" class="node"><title>GO:0005815</title>
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<polygon style="fill:none;stroke:black;" points="875,-210 875,-240 955,-240 955,-210 875,-210"/>
<text text-anchor="middle" x="915" y="-229.667" style="font-family:Arial;font-size:10px;">microtubule</text>
<text text-anchor="middle" x="915" y="-217.667" style="font-family:Arial;font-size:10px;">organizing center</text>
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<polygon style="fill:none;stroke:black;" points="875,-194 875,-210 955,-210 955,-194 875,-194"/>
<text text-anchor="middle" x="915" y="-199.667" style="font-family:Arial;font-size:10px;">Human</text>
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<polygon style="fill:none;stroke:black;" points="875,-178 875,-194 955,-194 955,-178 875,-178"/>
<text text-anchor="middle" x="915" y="-183.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0044450 -->
<g id="node121" class="node"><title>GO:0044450</title>
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<polygon style="fill:none;stroke:black;" points="799,-94 799,-136 879,-136 879,-94 799,-94"/>
<text text-anchor="middle" x="839" y="-125.667" style="font-family:Arial;font-size:10px;">microtubule</text>
<text text-anchor="middle" x="839" y="-113.667" style="font-family:Arial;font-size:10px;">organizing center</text>
<text text-anchor="middle" x="839" y="-101.667" style="font-family:Arial;font-size:10px;">part</text>
</g>
<!-- GO:0005815&#45;&gt;GO:0044450 -->
<g id="edge311" class="edge"><title>GO:0005815&#45;&gt;GO:0044450</title>
<path style="fill:none;stroke:blue;" d="M899,-171C888,-161 874,-147 862,-136"/>
<polygon style="fill:blue;stroke:blue;" points="896.454,-173.404 906,-178 901.404,-168.454 896.454,-173.404"/>
</g>
<!-- GO:0005813 -->
<g id="node122" class="node"><title>GO:0005813</title>
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<polygon style="fill:none;stroke:black;" points="913,-107 913,-123 971,-123 971,-107 913,-107"/>
<text text-anchor="middle" x="942" y="-112.667" style="font-family:Arial;font-size:10px;">centrosome</text>
</g>
<!-- GO:0005815&#45;&gt;GO:0005813 -->
<g id="edge315" class="edge"><title>GO:0005815&#45;&gt;GO:0005813</title>
<path style="fill:none;stroke:gray;" d="M922,-169C927,-154 935,-134 939,-123"/>
<polygon style="fill:gray;stroke:gray;" points="918.863,-167.44 918,-178 925.26,-170.283 918.863,-167.44"/>
</g>
<!-- GO:0006094 -->
<g id="node25" class="node"><title>GO:0006094</title>
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<text text-anchor="middle" x="2752" y="-301.667" style="font-family:Arial;font-size:10px;">gluconeogenesis</text>
<text text-anchor="middle" x="2752" y="-289.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0004332 -->
<g id="node26" class="node"><title>GO:0004332</title>
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<polygon style="fill:none;stroke:black;" points="430,-522 430,-564 532,-564 532,-522 430,-522"/>
<text text-anchor="middle" x="481" y="-553.667" style="font-family:Arial;font-size:10px;">fructose&#45;bisphosphate</text>
<text text-anchor="middle" x="481" y="-541.667" style="font-family:Arial;font-size:10px;">aldolase activity</text>
<text text-anchor="middle" x="481" y="-529.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0034451 -->
<g id="node27" class="node"><title>GO:0034451</title>
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<polygon style="fill:none;stroke:black;" points="850,-36 850,-52 932,-52 932,-36 850,-36"/>
<text text-anchor="middle" x="891" y="-41.6667" style="font-family:Arial;font-size:10px;">centriolar satellite</text>
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<polygon style="fill:none;stroke:black;" points="850,-20 850,-36 932,-36 932,-20 850,-20"/>
<text text-anchor="middle" x="891" y="-25.6667" style="font-family:Arial;font-size:10px;">Human</text>
<polygon style="fill:gold;stroke:gold;" points="850,-4 850,-20 932,-20 932,-4 850,-4"/>
<polygon style="fill:none;stroke:black;" points="850,-4 850,-20 932,-20 932,-4 850,-4"/>
<text text-anchor="middle" x="891" y="-9.66667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0019899 -->
<g id="node28" class="node"><title>GO:0019899</title>
<polygon style="fill:white;stroke:white;" points="220,-711 220,-727 294,-727 294,-711 220,-711"/>
<polygon style="fill:none;stroke:black;" points="220,-711 220,-727 294,-727 294,-711 220,-711"/>
<text text-anchor="middle" x="257" y="-716.667" style="font-family:Arial;font-size:10px;">enzyme binding</text>
</g>
<!-- GO:0019899&#45;&gt;GO:0051117 -->
<g id="edge3" class="edge"><title>GO:0019899&#45;&gt;GO:0051117</title>
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<polygon style="fill:gray;stroke:gray;" points="252.522,-701.398 257,-711 259.488,-700.701 252.522,-701.398"/>
</g>
<!-- GO:0005515 -->
<g id="node29" class="node"><title>GO:0005515</title>
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<polygon style="fill:none;stroke:black;" points="169,-789 169,-805 239,-805 239,-789 169,-789"/>
<text text-anchor="middle" x="204" y="-794.667" style="font-family:Arial;font-size:10px;">protein binding</text>
</g>
<!-- GO:0005515&#45;&gt;GO:0042802 -->
<g id="edge59" class="edge"><title>GO:0005515&#45;&gt;GO:0042802</title>
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</g>
<!-- GO:0005515&#45;&gt;GO:0008092 -->
<g id="edge117" class="edge"><title>GO:0005515&#45;&gt;GO:0008092</title>
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</g>
<!-- GO:0005515&#45;&gt;GO:0019899 -->
<g id="edge5" class="edge"><title>GO:0005515&#45;&gt;GO:0019899</title>
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<polygon style="fill:gray;stroke:gray;" points="211.635,-778.738 209,-789 217.459,-782.621 211.635,-778.738"/>
</g>
<!-- GO:0005488&#45;&gt;GO:0005515 -->
<g id="edge7" class="edge"><title>GO:0005488&#45;&gt;GO:0005515</title>
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</g>
<!-- GO:0030246 -->
<g id="node97" class="node"><title>GO:0030246</title>
<polygon style="fill:white;stroke:white;" points="332,-782 332,-812 394,-812 394,-782 332,-782"/>
<polygon style="fill:none;stroke:black;" points="332,-782 332,-812 394,-812 394,-782 332,-782"/>
<text text-anchor="middle" x="363" y="-801.667" style="font-family:Arial;font-size:10px;">carbohydrate</text>
<text text-anchor="middle" x="363" y="-789.667" style="font-family:Arial;font-size:10px;">binding</text>
</g>
<!-- GO:0005488&#45;&gt;GO:0030246 -->
<g id="edge217" class="edge"><title>GO:0005488&#45;&gt;GO:0030246</title>
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<polygon style="fill:gray;stroke:gray;" points="359.5,-841 363,-851 366.5,-841 359.5,-841"/>
</g>
<!-- GO:0044444 -->
<g id="node31" class="node"><title>GO:0044444</title>
<polygon style="fill:white;stroke:white;" points="625,-444 625,-474 683,-474 683,-444 625,-444"/>
<polygon style="fill:none;stroke:black;" points="625,-444 625,-474 683,-474 683,-444 625,-444"/>
<text text-anchor="middle" x="654" y="-463.667" style="font-family:Arial;font-size:10px;">cytoplasmic</text>
<text text-anchor="middle" x="654" y="-451.667" style="font-family:Arial;font-size:10px;">part</text>
</g>
<!-- GO:0044444&#45;&gt;GO:0048471 -->
<g id="edge11" class="edge"><title>GO:0044444&#45;&gt;GO:0048471</title>
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</g>
<!-- GO:0044444&#45;&gt;GO:0005829 -->
<g id="edge195" class="edge"><title>GO:0044444&#45;&gt;GO:0005829</title>
<path style="fill:none;stroke:gray;" d="M639,-435C630,-422 620,-405 613,-393"/>
<polygon style="fill:gray;stroke:gray;" points="636.084,-436.958 644,-444 642.203,-433.559 636.084,-436.958"/>
</g>
<!-- GO:0044444&#45;&gt;GO:0005815 -->
<g id="edge245" class="edge"><title>GO:0044444&#45;&gt;GO:0005815</title>
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</g>
<!-- GO:0005773 -->
<g id="node38" class="node"><title>GO:0005773</title>
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<polygon style="fill:none;stroke:black;" points="734,-370 734,-386 772,-386 772,-370 734,-370"/>
<text text-anchor="middle" x="753" y="-375.667" style="font-family:Arial;font-size:10px;">vacuole</text>
</g>
<!-- GO:0044444&#45;&gt;GO:0005773 -->
<g id="edge49" class="edge"><title>GO:0044444&#45;&gt;GO:0005773</title>
<path style="fill:none;stroke:gray;" d="M681,-437C701,-421 728,-398 743,-386"/>
<polygon style="fill:gray;stroke:gray;" points="678.221,-434.781 673,-444 682.831,-440.049 678.221,-434.781"/>
</g>
<!-- GO:0044444&#45;&gt;GO:0044450 -->
<g id="edge309" class="edge"><title>GO:0044444&#45;&gt;GO:0044450</title>
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<polygon style="fill:gray;stroke:gray;" points="648.522,-434.398 653,-444 655.488,-433.701 648.522,-434.398"/>
</g>
<!-- GO:0044424 -->
<g id="node32" class="node"><title>GO:0044424</title>
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<polygon style="fill:none;stroke:black;" points="631,-614 631,-644 687,-644 687,-614 631,-614"/>
<text text-anchor="middle" x="659" y="-633.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="659" y="-621.667" style="font-family:Arial;font-size:10px;">part</text>
</g>
<!-- GO:0044424&#45;&gt;GO:0044444 -->
<g id="edge13" class="edge"><title>GO:0044424&#45;&gt;GO:0044444</title>
<path style="fill:none;stroke:gray;" d="M658,-604C657,-568 655,-504 654,-474"/>
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</g>
<!-- GO:0005737 -->
<g id="node36" class="node"><title>GO:0005737</title>
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<polygon style="fill:none;stroke:black;" points="566,-535 566,-551 618,-551 618,-535 566,-535"/>
<text text-anchor="middle" x="592" y="-540.667" style="font-family:Arial;font-size:10px;">cytoplasm</text>
</g>
<!-- GO:0044424&#45;&gt;GO:0005737 -->
<g id="edge29" class="edge"><title>GO:0044424&#45;&gt;GO:0005737</title>
<path style="fill:none;stroke:gray;" d="M641,-606C627,-587 608,-563 598,-551"/>
<polygon style="fill:gray;stroke:gray;" points="638.2,-608.1 647,-614 643.8,-603.9 638.2,-608.1"/>
</g>
<!-- GO:0043229 -->
<g id="node42" class="node"><title>GO:0043229</title>
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<polygon style="fill:none;stroke:black;" points="826,-528 826,-558 882,-558 882,-528 826,-528"/>
<text text-anchor="middle" x="854" y="-547.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="854" y="-535.667" style="font-family:Arial;font-size:10px;">organelle</text>
</g>
<!-- GO:0044424&#45;&gt;GO:0043229 -->
<g id="edge47" class="edge"><title>GO:0044424&#45;&gt;GO:0043229</title>
<path style="fill:none;stroke:gray;" d="M697,-618C728,-608 773,-593 809,-574 818,-569 826,-564 834,-558"/>
<polygon style="fill:gray;stroke:gray;" points="695.573,-614.774 687,-621 697.584,-621.479 695.573,-614.774"/>
</g>
<!-- GO:0044446 -->
<g id="node99" class="node"><title>GO:0044446</title>
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<polygon style="fill:none;stroke:black;" points="723,-444 723,-474 787,-474 787,-444 723,-444"/>
<text text-anchor="middle" x="755" y="-463.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="755" y="-451.667" style="font-family:Arial;font-size:10px;">organelle part</text>
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<!-- GO:0044424&#45;&gt;GO:0044446 -->
<g id="edge231" class="edge"><title>GO:0044424&#45;&gt;GO:0044446</title>
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<g id="edge15" class="edge"><title>GO:0044464&#45;&gt;GO:0044424</title>
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<g id="edge25" class="edge"><title>GO:0044464&#45;&gt;GO:0005622</title>
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<g id="edge19" class="edge"><title>GO:0005623&#45;&gt;GO:0044464</title>
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<g id="edge23" class="edge"><title>GO:0005622&#45;&gt;GO:0044424</title>
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<g id="edge27" class="edge"><title>GO:0005737&#45;&gt;GO:0044444</title>
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<g id="edge31" class="edge"><title>GO:0000323&#45;&gt;GO:0005764</title>
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<g id="edge33" class="edge"><title>GO:0005773&#45;&gt;GO:0000323</title>
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<g id="node39" class="node"><title>GO:0043231</title>
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<g id="edge145" class="edge"><title>GO:0043231&#45;&gt;GO:0005634</title>
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<g id="edge35" class="edge"><title>GO:0043231&#45;&gt;GO:0005773</title>
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<g id="node40" class="node"><title>GO:0043227</title>
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<text text-anchor="middle" x="962" y="-535.667" style="font-family:Arial;font-size:10px;">organelle</text>
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<g id="edge37" class="edge"><title>GO:0043227&#45;&gt;GO:0043231</title>
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<g id="edge39" class="edge"><title>GO:0043226&#45;&gt;GO:0043227</title>
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<g id="edge45" class="edge"><title>GO:0043226&#45;&gt;GO:0043229</title>
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<g id="edge229" class="edge"><title>GO:0043226&#45;&gt;GO:0044422</title>
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<g id="node103" class="node"><title>GO:0043228</title>
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<polygon style="fill:none;stroke:black;" points="1042,-528 1042,-558 1152,-558 1152,-528 1042,-528"/>
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<!-- GO:0043226&#45;&gt;GO:0043228 -->
<g id="edge241" class="edge"><title>GO:0043226&#45;&gt;GO:0043228</title>
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<!-- GO:0043229&#45;&gt;GO:0043231 -->
<g id="edge43" class="edge"><title>GO:0043229&#45;&gt;GO:0043231</title>
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<g id="edge233" class="edge"><title>GO:0043229&#45;&gt;GO:0044446</title>
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<!-- GO:0043232 -->
<g id="node102" class="node"><title>GO:0043232</title>
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<text text-anchor="middle" x="1008" y="-457.667" style="font-family:Arial;font-size:10px;">non&#45;membrane&#45;bounded</text>
<text text-anchor="middle" x="1008" y="-445.667" style="font-family:Arial;font-size:10px;">organelle</text>
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<g id="edge243" class="edge"><title>GO:0043229&#45;&gt;GO:0043232</title>
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<!-- GO:0010033&#45;&gt;GO:0009743 -->
<g id="edge51" class="edge"><title>GO:0010033&#45;&gt;GO:0009743</title>
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<!-- GO:0050896&#45;&gt;GO:0042221 -->
<g id="edge55" class="edge"><title>GO:0050896&#45;&gt;GO:0042221</title>
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<text text-anchor="middle" x="1182" y="-789.667" style="font-family:Arial;font-size:10px;">stress</text>
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<!-- GO:0050896&#45;&gt;GO:0006950 -->
<g id="edge149" class="edge"><title>GO:0050896&#45;&gt;GO:0006950</title>
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<!-- GO:0009605 -->
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<polygon style="fill:none;stroke:black;" points="1249,-782 1249,-812 1329,-812 1329,-782 1249,-782"/>
<text text-anchor="middle" x="1289" y="-801.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1289" y="-789.667" style="font-family:Arial;font-size:10px;">external stimulus</text>
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<!-- GO:0050896&#45;&gt;GO:0009605 -->
<g id="edge157" class="edge"><title>GO:0050896&#45;&gt;GO:0009605</title>
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<g id="node94" class="node"><title>GO:0009719</title>
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<text text-anchor="middle" x="1414" y="-789.667" style="font-family:Arial;font-size:10px;">endogenous stimulus</text>
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<!-- GO:0050896&#45;&gt;GO:0009719 -->
<g id="edge207" class="edge"><title>GO:0050896&#45;&gt;GO:0009719</title>
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<g id="node45" class="node"><title>GO:0043462</title>
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<polygon style="fill:none;stroke:black;" points="1846,-528 1846,-558 1920,-558 1920,-528 1846,-528"/>
<text text-anchor="middle" x="1883" y="-547.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="1883" y="-535.667" style="font-family:Arial;font-size:10px;">ATPase activity</text>
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<!-- GO:0043462&#45;&gt;GO:0032781 -->
<g id="edge61" class="edge"><title>GO:0043462&#45;&gt;GO:0032781</title>
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<g id="node46" class="node"><title>GO:0051336</title>
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<polygon style="fill:none;stroke:black;" points="1844,-614 1844,-644 1926,-644 1926,-614 1844,-614"/>
<text text-anchor="middle" x="1885" y="-633.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="1885" y="-621.667" style="font-family:Arial;font-size:10px;">hydrolase activity</text>
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<!-- GO:0051336&#45;&gt;GO:0043462 -->
<g id="edge63" class="edge"><title>GO:0051336&#45;&gt;GO:0043462</title>
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<g id="node50" class="node"><title>GO:0051345</title>
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<!-- GO:0051336&#45;&gt;GO:0051345 -->
<g id="edge79" class="edge"><title>GO:0051336&#45;&gt;GO:0051345</title>
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<!-- GO:0050790&#45;&gt;GO:0051336 -->
<g id="edge65" class="edge"><title>GO:0050790&#45;&gt;GO:0051336</title>
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<g id="edge77" class="edge"><title>GO:0050790&#45;&gt;GO:0043085</title>
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<!-- GO:0065009&#45;&gt;GO:0050790 -->
<g id="edge67" class="edge"><title>GO:0065009&#45;&gt;GO:0050790</title>
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<g id="edge69" class="edge"><title>GO:0065007&#45;&gt;GO:0065009</title>
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<g id="edge73" class="edge"><title>GO:0051345&#45;&gt;GO:0032781</title>
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<g id="edge75" class="edge"><title>GO:0043085&#45;&gt;GO:0051345</title>
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<!-- GO:0010038&#45;&gt;GO:0046688 -->
<g id="edge81" class="edge"><title>GO:0010038&#45;&gt;GO:0046688</title>
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<g id="edge197" class="edge"><title>GO:0010038&#45;&gt;GO:0010043</title>
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<g id="edge83" class="edge"><title>GO:0010035&#45;&gt;GO:0010038</title>
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<text text-anchor="middle" x="2058" y="-219.667" style="font-family:Arial;font-size:10px;">proton&#45;transporting</text>
<text text-anchor="middle" x="2058" y="-207.667" style="font-family:Arial;font-size:10px;">V&#45;type ATPase</text>
<text text-anchor="middle" x="2058" y="-195.667" style="font-family:Arial;font-size:10px;">complex assembly</text>
</g>
<!-- GO:0070070&#45;&gt;GO:0070072 -->
<g id="edge87" class="edge"><title>GO:0070070&#45;&gt;GO:0070072</title>
<path style="fill:none;stroke:gray;" d="M2058,-178C2058,-169 2058,-160 2058,-152"/>
<polygon style="fill:gray;stroke:gray;" points="2054.5,-178 2058,-188 2061.5,-178 2054.5,-178"/>
</g>
<!-- GO:0070071 -->
<g id="node55" class="node"><title>GO:0070071</title>
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<polygon style="fill:none;stroke:black;" points="2014,-276 2014,-318 2102,-318 2102,-276 2014,-276"/>
<text text-anchor="middle" x="2058" y="-307.667" style="font-family:Arial;font-size:10px;">proton&#45;transporting</text>
<text text-anchor="middle" x="2058" y="-295.667" style="font-family:Arial;font-size:10px;">two&#45;sector ATPase</text>
<text text-anchor="middle" x="2058" y="-283.667" style="font-family:Arial;font-size:10px;">complex assembly</text>
</g>
<!-- GO:0070071&#45;&gt;GO:0070070 -->
<g id="edge89" class="edge"><title>GO:0070071&#45;&gt;GO:0070070</title>
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<polygon style="fill:gray;stroke:gray;" points="2054.5,-266 2058,-276 2061.5,-266 2054.5,-266"/>
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<!-- GO:0043623 -->
<g id="node56" class="node"><title>GO:0043623</title>
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<polygon style="fill:none;stroke:black;" points="2014,-363 2014,-393 2102,-393 2102,-363 2014,-363"/>
<text text-anchor="middle" x="2058" y="-382.667" style="font-family:Arial;font-size:10px;">cellular protein</text>
<text text-anchor="middle" x="2058" y="-370.667" style="font-family:Arial;font-size:10px;">complex assembly</text>
</g>
<!-- GO:0043623&#45;&gt;GO:0070071 -->
<g id="edge91" class="edge"><title>GO:0043623&#45;&gt;GO:0070071</title>
<path style="fill:none;stroke:gray;" d="M2058,-353C2058,-342 2058,-329 2058,-318"/>
<polygon style="fill:gray;stroke:gray;" points="2054.5,-353 2058,-363 2061.5,-353 2054.5,-353"/>
</g>
<!-- GO:0006461 -->
<g id="node57" class="node"><title>GO:0006461</title>
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<polygon style="fill:none;stroke:black;" points="1957,-444 1957,-474 2033,-474 2033,-444 1957,-444"/>
<text text-anchor="middle" x="1995" y="-463.667" style="font-family:Arial;font-size:10px;">protein complex</text>
<text text-anchor="middle" x="1995" y="-451.667" style="font-family:Arial;font-size:10px;">assembly</text>
</g>
<!-- GO:0006461&#45;&gt;GO:0043623 -->
<g id="edge93" class="edge"><title>GO:0006461&#45;&gt;GO:0043623</title>
<path style="fill:none;stroke:gray;" d="M2013,-436C2024,-422 2037,-405 2046,-393"/>
<polygon style="fill:gray;stroke:gray;" points="2010.2,-433.9 2007,-444 2015.8,-438.1 2010.2,-433.9"/>
</g>
<!-- GO:0065003 -->
<g id="node58" class="node"><title>GO:0065003</title>
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<polygon style="fill:none;stroke:black;" points="1954,-528 1954,-558 2042,-558 2042,-528 1954,-528"/>
<text text-anchor="middle" x="1998" y="-547.667" style="font-family:Arial;font-size:10px;">macromolecular</text>
<text text-anchor="middle" x="1998" y="-535.667" style="font-family:Arial;font-size:10px;">complex assembly</text>
</g>
<!-- GO:0065003&#45;&gt;GO:0006461 -->
<g id="edge95" class="edge"><title>GO:0065003&#45;&gt;GO:0006461</title>
<path style="fill:none;stroke:gray;" d="M1997,-518C1997,-504 1996,-487 1996,-474"/>
<polygon style="fill:gray;stroke:gray;" points="1993.5,-518 1997,-528 2000.5,-518 1993.5,-518"/>
</g>
<!-- GO:0034622 -->
<g id="node63" class="node"><title>GO:0034622</title>
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<polygon style="fill:none;stroke:black;" points="2067,-444 2067,-474 2175,-474 2175,-444 2067,-444"/>
<text text-anchor="middle" x="2121" y="-463.667" style="font-family:Arial;font-size:10px;">cellular macromolecular</text>
<text text-anchor="middle" x="2121" y="-451.667" style="font-family:Arial;font-size:10px;">complex assembly</text>
</g>
<!-- GO:0065003&#45;&gt;GO:0034622 -->
<g id="edge115" class="edge"><title>GO:0065003&#45;&gt;GO:0034622</title>
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<polygon style="fill:gray;stroke:gray;" points="2025.9,-519.2 2020,-528 2030.1,-524.8 2025.9,-519.2"/>
</g>
<!-- GO:0022607 -->
<g id="node59" class="node"><title>GO:0022607</title>
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<polygon style="fill:none;stroke:black;" points="1960,-614 1960,-644 2048,-644 2048,-614 1960,-614"/>
<text text-anchor="middle" x="2004" y="-633.667" style="font-family:Arial;font-size:10px;">cellular component</text>
<text text-anchor="middle" x="2004" y="-621.667" style="font-family:Arial;font-size:10px;">assembly</text>
</g>
<!-- GO:0022607&#45;&gt;GO:0065003 -->
<g id="edge97" class="edge"><title>GO:0022607&#45;&gt;GO:0065003</title>
<path style="fill:none;stroke:gray;" d="M2002,-604C2001,-589 2000,-571 1999,-558"/>
<polygon style="fill:gray;stroke:gray;" points="1998.52,-604.398 2003,-614 2005.49,-603.701 1998.52,-604.398"/>
</g>
<!-- GO:0016043 -->
<g id="node60" class="node"><title>GO:0016043</title>
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<polygon style="fill:none;stroke:black;" points="2019,-704 2019,-734 2107,-734 2107,-704 2019,-704"/>
<text text-anchor="middle" x="2063" y="-723.667" style="font-family:Arial;font-size:10px;">cellular component</text>
<text text-anchor="middle" x="2063" y="-711.667" style="font-family:Arial;font-size:10px;">organization</text>
</g>
<!-- GO:0016043&#45;&gt;GO:0022607 -->
<g id="edge99" class="edge"><title>GO:0016043&#45;&gt;GO:0022607</title>
<path style="fill:none;stroke:gray;" d="M2047,-695C2037,-679 2023,-658 2014,-644"/>
<polygon style="fill:gray;stroke:gray;" points="2044.54,-697.621 2053,-704 2050.37,-693.738 2044.54,-697.621"/>
</g>
<!-- GO:0043933 -->
<g id="node62" class="node"><title>GO:0043933</title>
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<polygon style="fill:none;stroke:black;" points="2082,-608 2082,-650 2160,-650 2160,-608 2082,-608"/>
<text text-anchor="middle" x="2121" y="-639.667" style="font-family:Arial;font-size:10px;">macromolecular</text>
<text text-anchor="middle" x="2121" y="-627.667" style="font-family:Arial;font-size:10px;">complex subunit</text>
<text text-anchor="middle" x="2121" y="-615.667" style="font-family:Arial;font-size:10px;">organization</text>
</g>
<!-- GO:0016043&#45;&gt;GO:0043933 -->
<g id="edge107" class="edge"><title>GO:0016043&#45;&gt;GO:0043933</title>
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<polygon style="fill:gray;stroke:gray;" points="2074.8,-693.559 2073,-704 2080.92,-696.958 2074.8,-693.559"/>
</g>
<!-- GO:0009987&#45;&gt;GO:0016043 -->
<g id="edge101" class="edge"><title>GO:0009987&#45;&gt;GO:0016043</title>
<path style="fill:none;stroke:gray;" d="M2063,-779C2063,-765 2063,-747 2063,-734"/>
<polygon style="fill:gray;stroke:gray;" points="2059.5,-779 2063,-789 2066.5,-779 2059.5,-779"/>
</g>
<!-- GO:0044237 -->
<g id="node69" class="node"><title>GO:0044237</title>
<polygon style="fill:white;stroke:white;" points="2468,-704 2468,-734 2550,-734 2550,-704 2468,-704"/>
<polygon style="fill:none;stroke:black;" points="2468,-704 2468,-734 2550,-734 2550,-704 2468,-704"/>
<text text-anchor="middle" x="2509" y="-723.667" style="font-family:Arial;font-size:10px;">cellular metabolic</text>
<text text-anchor="middle" x="2509" y="-711.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0009987&#45;&gt;GO:0044237 -->
<g id="edge133" class="edge"><title>GO:0009987&#45;&gt;GO:0044237</title>
<path style="fill:none;stroke:gray;" d="M2110,-788C2198,-773 2385,-740 2468,-726"/>
<polygon style="fill:gray;stroke:gray;" points="2109.12,-784.607 2100,-790 2110.49,-791.471 2109.12,-784.607"/>
</g>
<!-- GO:0043933&#45;&gt;GO:0065003 -->
<g id="edge105" class="edge"><title>GO:0043933&#45;&gt;GO:0065003</title>
<path style="fill:none;stroke:gray;" d="M2082,-602C2061,-588 2037,-570 2019,-558"/>
<polygon style="fill:gray;stroke:gray;" points="2080.74,-605.365 2091,-608 2084.62,-599.541 2080.74,-605.365"/>
</g>
<!-- GO:0034621 -->
<g id="node64" class="node"><title>GO:0034621</title>
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<polygon style="fill:none;stroke:black;" points="2076,-522 2076,-564 2184,-564 2184,-522 2076,-522"/>
<text text-anchor="middle" x="2130" y="-553.667" style="font-family:Arial;font-size:10px;">cellular macromolecular</text>
<text text-anchor="middle" x="2130" y="-541.667" style="font-family:Arial;font-size:10px;">complex subunit</text>
<text text-anchor="middle" x="2130" y="-529.667" style="font-family:Arial;font-size:10px;">organization</text>
</g>
<!-- GO:0043933&#45;&gt;GO:0034621 -->
<g id="edge113" class="edge"><title>GO:0043933&#45;&gt;GO:0034621</title>
<path style="fill:none;stroke:gray;" d="M2124,-598C2126,-586 2126,-574 2128,-564"/>
<polygon style="fill:gray;stroke:gray;" points="2120.51,-597.701 2123,-608 2127.48,-598.398 2120.51,-597.701"/>
</g>
<!-- GO:0034622&#45;&gt;GO:0043623 -->
<g id="edge109" class="edge"><title>GO:0034622&#45;&gt;GO:0043623</title>
<path style="fill:none;stroke:gray;" d="M2103,-436C2092,-422 2079,-405 2070,-393"/>
<polygon style="fill:gray;stroke:gray;" points="2100.2,-438.1 2109,-444 2105.8,-433.9 2100.2,-438.1"/>
</g>
<!-- GO:0034621&#45;&gt;GO:0034622 -->
<g id="edge111" class="edge"><title>GO:0034621&#45;&gt;GO:0034622</title>
<path style="fill:none;stroke:gray;" d="M2127,-512C2125,-499 2124,-484 2123,-474"/>
<polygon style="fill:gray;stroke:gray;" points="2123.52,-512.398 2128,-522 2130.49,-511.701 2123.52,-512.398"/>
</g>
<!-- GO:0006000 -->
<g id="node65" class="node"><title>GO:0006000</title>
<polygon style="fill:white;stroke:white;" points="2956,-363 2956,-393 3042,-393 3042,-363 2956,-363"/>
<polygon style="fill:none;stroke:black;" points="2956,-363 2956,-393 3042,-393 3042,-363 2956,-363"/>
<text text-anchor="middle" x="2999" y="-382.667" style="font-family:Arial;font-size:10px;">fructose metabolic</text>
<text text-anchor="middle" x="2999" y="-370.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0006000&#45;&gt;GO:0030388 -->
<g id="edge119" class="edge"><title>GO:0006000&#45;&gt;GO:0030388</title>
<path style="fill:none;stroke:gray;" d="M2999,-353C2999,-345 2999,-336 2999,-328"/>
<polygon style="fill:gray;stroke:gray;" points="2995.5,-353 2999,-363 3002.5,-353 2995.5,-353"/>
</g>
<!-- GO:0019318 -->
<g id="node66" class="node"><title>GO:0019318</title>
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<polygon style="fill:none;stroke:black;" points="2729,-444 2729,-474 2811,-474 2811,-444 2729,-444"/>
<text text-anchor="middle" x="2770" y="-463.667" style="font-family:Arial;font-size:10px;">hexose metabolic</text>
<text text-anchor="middle" x="2770" y="-451.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0019318&#45;&gt;GO:0006000 -->
<g id="edge121" class="edge"><title>GO:0019318&#45;&gt;GO:0006000</title>
<path style="fill:none;stroke:gray;" d="M2801,-439C2810,-433 2821,-428 2832,-424 2877,-407 2892,-420 2939,-406 2950,-403 2961,-398 2971,-393"/>
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</g>
<!-- GO:0006006 -->
<g id="node105" class="node"><title>GO:0006006</title>
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<polygon style="fill:none;stroke:black;" points="2710,-363 2710,-393 2794,-393 2794,-363 2710,-363"/>
<text text-anchor="middle" x="2752" y="-382.667" style="font-family:Arial;font-size:10px;">glucose metabolic</text>
<text text-anchor="middle" x="2752" y="-370.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0019318&#45;&gt;GO:0006006 -->
<g id="edge253" class="edge"><title>GO:0019318&#45;&gt;GO:0006006</title>
<path style="fill:none;stroke:gray;" d="M2764,-434C2761,-421 2757,-405 2755,-393"/>
<polygon style="fill:gray;stroke:gray;" points="2760.77,-435.427 2767,-444 2767.48,-433.416 2760.77,-435.427"/>
</g>
<!-- GO:0019319 -->
<g id="node110" class="node"><title>GO:0019319</title>
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<polygon style="fill:none;stroke:black;" points="2828,-363 2828,-393 2922,-393 2922,-363 2828,-363"/>
<text text-anchor="middle" x="2875" y="-382.667" style="font-family:Arial;font-size:10px;">hexose biosynthetic</text>
<text text-anchor="middle" x="2875" y="-370.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0019318&#45;&gt;GO:0019319 -->
<g id="edge267" class="edge"><title>GO:0019318&#45;&gt;GO:0019319</title>
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<polygon style="fill:gray;stroke:gray;" points="2795.9,-435.2 2790,-444 2800.1,-440.8 2795.9,-435.2"/>
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<!-- GO:0005996 -->
<g id="node67" class="node"><title>GO:0005996</title>
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<polygon style="fill:none;stroke:black;" points="2724,-528 2724,-558 2810,-558 2810,-528 2724,-528"/>
<text text-anchor="middle" x="2767" y="-547.667" style="font-family:Arial;font-size:10px;">monosaccharide</text>
<text text-anchor="middle" x="2767" y="-535.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
</g>
<!-- GO:0005996&#45;&gt;GO:0019318 -->
<g id="edge123" class="edge"><title>GO:0005996&#45;&gt;GO:0019318</title>
<path style="fill:none;stroke:gray;" d="M2768,-518C2768,-504 2769,-487 2769,-474"/>
<polygon style="fill:gray;stroke:gray;" points="2764.5,-518 2768,-528 2771.5,-518 2764.5,-518"/>
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<!-- GO:0046364 -->
<g id="node111" class="node"><title>GO:0046364</title>
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<polygon style="fill:none;stroke:black;" points="2849,-438 2849,-480 2927,-480 2927,-438 2849,-438"/>
<text text-anchor="middle" x="2888" y="-469.667" style="font-family:Arial;font-size:10px;">monosaccharide</text>
<text text-anchor="middle" x="2888" y="-457.667" style="font-family:Arial;font-size:10px;">biosynthetic</text>
<text text-anchor="middle" x="2888" y="-445.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0005996&#45;&gt;GO:0046364 -->
<g id="edge271" class="edge"><title>GO:0005996&#45;&gt;GO:0046364</title>
<path style="fill:none;stroke:gray;" d="M2798,-522C2816,-509 2839,-493 2857,-480"/>
<polygon style="fill:gray;stroke:gray;" points="2795.38,-519.541 2789,-528 2799.26,-525.365 2795.38,-519.541"/>
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<!-- GO:0006066 -->
<g id="node68" class="node"><title>GO:0006066</title>
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<polygon style="fill:none;stroke:black;" points="2756,-614 2756,-644 2842,-644 2842,-614 2756,-614"/>
<text text-anchor="middle" x="2799" y="-633.667" style="font-family:Arial;font-size:10px;">cellular alcohol</text>
<text text-anchor="middle" x="2799" y="-621.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
</g>
<!-- GO:0006066&#45;&gt;GO:0005996 -->
<g id="edge125" class="edge"><title>GO:0006066&#45;&gt;GO:0005996</title>
<path style="fill:none;stroke:gray;" d="M2789,-604C2784,-589 2777,-571 2773,-558"/>
<polygon style="fill:gray;stroke:gray;" points="2786.04,-606.015 2793,-614 2792.54,-603.415 2786.04,-606.015"/>
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<!-- GO:0046165 -->
<g id="node116" class="node"><title>GO:0046165</title>
<polygon style="fill:white;stroke:white;" points="2844,-528 2844,-558 2936,-558 2936,-528 2844,-528"/>
<polygon style="fill:none;stroke:black;" points="2844,-528 2844,-558 2936,-558 2936,-528 2844,-528"/>
<text text-anchor="middle" x="2890" y="-547.667" style="font-family:Arial;font-size:10px;">alcohol biosynthetic</text>
<text text-anchor="middle" x="2890" y="-535.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0006066&#45;&gt;GO:0046165 -->
<g id="edge291" class="edge"><title>GO:0006066&#45;&gt;GO:0046165</title>
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<!-- GO:0044237&#45;&gt;GO:0006066 -->
<g id="edge127" class="edge"><title>GO:0044237&#45;&gt;GO:0006066</title>
<path style="fill:none;stroke:gray;" d="M2558,-701C2575,-695 2595,-688 2614,-684 2668,-671 2686,-685 2739,-666 2753,-661 2768,-652 2779,-644"/>
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<!-- GO:0044262 -->
<g id="node71" class="node"><title>GO:0044262</title>
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<polygon style="fill:none;stroke:black;" points="2626,-614 2626,-644 2722,-644 2722,-614 2626,-614"/>
<text text-anchor="middle" x="2674" y="-633.667" style="font-family:Arial;font-size:10px;">cellular carbohydrate</text>
<text text-anchor="middle" x="2674" y="-621.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
</g>
<!-- GO:0044237&#45;&gt;GO:0044262 -->
<g id="edge143" class="edge"><title>GO:0044237&#45;&gt;GO:0044262</title>
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<!-- GO:0051186 -->
<g id="node83" class="node"><title>GO:0051186</title>
<polygon style="fill:white;stroke:white;" points="2348,-528 2348,-558 2434,-558 2434,-528 2348,-528"/>
<polygon style="fill:none;stroke:black;" points="2348,-528 2348,-558 2434,-558 2434,-528 2348,-528"/>
<text text-anchor="middle" x="2391" y="-547.667" style="font-family:Arial;font-size:10px;">cofactor metabolic</text>
<text text-anchor="middle" x="2391" y="-535.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0044237&#45;&gt;GO:0051186 -->
<g id="edge171" class="edge"><title>GO:0044237&#45;&gt;GO:0051186</title>
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<!-- GO:0006766 -->
<g id="node85" class="node"><title>GO:0006766</title>
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<polygon style="fill:none;stroke:black;" points="2473,-444 2473,-474 2555,-474 2555,-444 2473,-444"/>
<text text-anchor="middle" x="2514" y="-463.667" style="font-family:Arial;font-size:10px;">vitamin metabolic</text>
<text text-anchor="middle" x="2514" y="-451.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0044237&#45;&gt;GO:0006766 -->
<g id="edge177" class="edge"><title>GO:0044237&#45;&gt;GO:0006766</title>
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<!-- GO:0006139 -->
<g id="node89" class="node"><title>GO:0006139</title>
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<text text-anchor="middle" x="2353" y="-651.667" style="font-family:Arial;font-size:10px;">nucleobase,</text>
<text text-anchor="middle" x="2353" y="-639.667" style="font-family:Arial;font-size:10px;">nucleoside,</text>
<text text-anchor="middle" x="2353" y="-627.667" style="font-family:Arial;font-size:10px;">nucleotide and</text>
<text text-anchor="middle" x="2353" y="-615.667" style="font-family:Arial;font-size:10px;">nucleic acid</text>
<text text-anchor="middle" x="2353" y="-603.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0044237&#45;&gt;GO:0006139 -->
<g id="edge187" class="edge"><title>GO:0044237&#45;&gt;GO:0006139</title>
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<!-- GO:0006082 -->
<g id="node109" class="node"><title>GO:0006082</title>
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<text text-anchor="middle" x="2549" y="-633.667" style="font-family:Arial;font-size:10px;">organic acid</text>
<text text-anchor="middle" x="2549" y="-621.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0044237&#45;&gt;GO:0006082 -->
<g id="edge263" class="edge"><title>GO:0044237&#45;&gt;GO:0006082</title>
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<!-- GO:0044249 -->
<g id="node115" class="node"><title>GO:0044249</title>
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<text text-anchor="middle" x="2922" y="-633.667" style="font-family:Arial;font-size:10px;">cellular biosynthetic</text>
<text text-anchor="middle" x="2922" y="-621.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0044237&#45;&gt;GO:0044249 -->
<g id="edge287" class="edge"><title>GO:0044237&#45;&gt;GO:0044249</title>
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<g id="edge129" class="edge"><title>GO:0008152&#45;&gt;GO:0044237</title>
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<!-- GO:0044238 -->
<g id="node73" class="node"><title>GO:0044238</title>
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<text text-anchor="middle" x="2431" y="-801.667" style="font-family:Arial;font-size:10px;">primary metabolic</text>
<text text-anchor="middle" x="2431" y="-789.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0008152&#45;&gt;GO:0044238 -->
<g id="edge141" class="edge"><title>GO:0008152&#45;&gt;GO:0044238</title>
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<!-- GO:0009058 -->
<g id="node114" class="node"><title>GO:0009058</title>
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<text text-anchor="middle" x="2922" y="-723.667" style="font-family:Arial;font-size:10px;">biosynthetic</text>
<text text-anchor="middle" x="2922" y="-711.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0008152&#45;&gt;GO:0009058 -->
<g id="edge281" class="edge"><title>GO:0008152&#45;&gt;GO:0009058</title>
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<!-- GO:0044262&#45;&gt;GO:0005996 -->
<g id="edge135" class="edge"><title>GO:0044262&#45;&gt;GO:0005996</title>
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<!-- GO:0005975 -->
<g id="node72" class="node"><title>GO:0005975</title>
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<text text-anchor="middle" x="2674" y="-723.667" style="font-family:Arial;font-size:10px;">carbohydrate</text>
<text text-anchor="middle" x="2674" y="-711.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0005975&#45;&gt;GO:0044262 -->
<g id="edge137" class="edge"><title>GO:0005975&#45;&gt;GO:0044262</title>
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<polygon style="fill:gray;stroke:gray;" points="2670.5,-694 2674,-704 2677.5,-694 2670.5,-694"/>
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<!-- GO:0016051 -->
<g id="node113" class="node"><title>GO:0016051</title>
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<polygon style="fill:none;stroke:black;" points="3002,-608 3002,-650 3064,-650 3064,-608 3002,-608"/>
<text text-anchor="middle" x="3033" y="-639.667" style="font-family:Arial;font-size:10px;">carbohydrate</text>
<text text-anchor="middle" x="3033" y="-627.667" style="font-family:Arial;font-size:10px;">biosynthetic</text>
<text text-anchor="middle" x="3033" y="-615.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0005975&#45;&gt;GO:0016051 -->
<g id="edge277" class="edge"><title>GO:0005975&#45;&gt;GO:0016051</title>
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<polygon style="fill:gray;stroke:gray;" points="2726.12,-705.607 2717,-711 2727.49,-712.471 2726.12,-705.607"/>
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<!-- GO:0044238&#45;&gt;GO:0005975 -->
<g id="edge139" class="edge"><title>GO:0044238&#45;&gt;GO:0005975</title>
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<polygon style="fill:gray;stroke:gray;" points="2481.57,-777.774 2473,-784 2483.58,-784.479 2481.57,-777.774"/>
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<!-- GO:0044238&#45;&gt;GO:0006139 -->
<g id="edge189" class="edge"><title>GO:0044238&#45;&gt;GO:0006139</title>
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<!-- GO:0006950&#45;&gt;GO:0042594 -->
<g id="edge147" class="edge"><title>GO:0006950&#45;&gt;GO:0042594</title>
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<!-- GO:0031667 -->
<g id="node75" class="node"><title>GO:0031667</title>
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<polygon style="fill:none;stroke:black;" points="1216,-614 1216,-644 1282,-644 1282,-614 1216,-614"/>
<text text-anchor="middle" x="1249" y="-633.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1249" y="-621.667" style="font-family:Arial;font-size:10px;">nutrient levels</text>
</g>
<!-- GO:0031667&#45;&gt;GO:0042594 -->
<g id="edge151" class="edge"><title>GO:0031667&#45;&gt;GO:0042594</title>
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<!-- GO:0009991 -->
<g id="node76" class="node"><title>GO:0009991</title>
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<text text-anchor="middle" x="1269" y="-729.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1269" y="-717.667" style="font-family:Arial;font-size:10px;">extracellular</text>
<text text-anchor="middle" x="1269" y="-705.667" style="font-family:Arial;font-size:10px;">stimulus</text>
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<!-- GO:0009991&#45;&gt;GO:0031667 -->
<g id="edge153" class="edge"><title>GO:0009991&#45;&gt;GO:0031667</title>
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<!-- GO:0009605&#45;&gt;GO:0009991 -->
<g id="edge155" class="edge"><title>GO:0009605&#45;&gt;GO:0009991</title>
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<polygon style="fill:gray;stroke:gray;" points="1279.61,-772.881 1285,-782 1286.47,-771.508 1279.61,-772.881"/>
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<!-- GO:0006734 -->
<g id="node78" class="node"><title>GO:0006734</title>
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<text text-anchor="middle" x="2335" y="-119.667" style="font-family:Arial;font-size:10px;">NADH metabolic</text>
<text text-anchor="middle" x="2335" y="-107.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0006734&#45;&gt;GO:0006116 -->
<g id="edge159" class="edge"><title>GO:0006734&#45;&gt;GO:0006116</title>
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<polygon style="fill:gray;stroke:gray;" points="2349.2,-89.9 2346,-100 2354.8,-94.1 2349.2,-89.9"/>
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<!-- GO:0006769 -->
<g id="node79" class="node"><title>GO:0006769</title>
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<text text-anchor="middle" x="2390" y="-213.667" style="font-family:Arial;font-size:10px;">nicotinamide</text>
<text text-anchor="middle" x="2390" y="-201.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0006769&#45;&gt;GO:0006734 -->
<g id="edge161" class="edge"><title>GO:0006769&#45;&gt;GO:0006734</title>
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<!-- GO:0019674 -->
<g id="node90" class="node"><title>GO:0019674</title>
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<text text-anchor="middle" x="2444" y="-119.667" style="font-family:Arial;font-size:10px;">NAD metabolic</text>
<text text-anchor="middle" x="2444" y="-107.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0006769&#45;&gt;GO:0019674 -->
<g id="edge193" class="edge"><title>GO:0006769&#45;&gt;GO:0019674</title>
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<!-- GO:0019362 -->
<g id="node80" class="node"><title>GO:0019362</title>
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<polygon style="fill:none;stroke:black;" points="2346,-282 2346,-312 2434,-312 2434,-282 2346,-282"/>
<text text-anchor="middle" x="2390" y="-301.667" style="font-family:Arial;font-size:10px;">pyridine nucleotide</text>
<text text-anchor="middle" x="2390" y="-289.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0019362&#45;&gt;GO:0006769 -->
<g id="edge163" class="edge"><title>GO:0019362&#45;&gt;GO:0006769</title>
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<!-- GO:0006733 -->
<g id="node81" class="node"><title>GO:0006733</title>
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<polygon style="fill:none;stroke:black;" points="2342,-357 2342,-399 2438,-399 2438,-357 2342,-357"/>
<text text-anchor="middle" x="2390" y="-388.667" style="font-family:Arial;font-size:10px;">oxidoreduction</text>
<text text-anchor="middle" x="2390" y="-376.667" style="font-family:Arial;font-size:10px;">coenzyme metabolic</text>
<text text-anchor="middle" x="2390" y="-364.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0006733&#45;&gt;GO:0019362 -->
<g id="edge165" class="edge"><title>GO:0006733&#45;&gt;GO:0019362</title>
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<!-- GO:0006732 -->
<g id="node82" class="node"><title>GO:0006732</title>
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<text text-anchor="middle" x="2391" y="-451.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0006732&#45;&gt;GO:0006733 -->
<g id="edge167" class="edge"><title>GO:0006732&#45;&gt;GO:0006733</title>
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<!-- GO:0051186&#45;&gt;GO:0006732 -->
<g id="edge169" class="edge"><title>GO:0051186&#45;&gt;GO:0006732</title>
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<!-- GO:0006767 -->
<g id="node84" class="node"><title>GO:0006767</title>
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<text text-anchor="middle" x="2513" y="-388.667" style="font-family:Arial;font-size:10px;">water&#45;soluble</text>
<text text-anchor="middle" x="2513" y="-376.667" style="font-family:Arial;font-size:10px;">vitamin metabolic</text>
<text text-anchor="middle" x="2513" y="-364.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0006767&#45;&gt;GO:0019362 -->
<g id="edge173" class="edge"><title>GO:0006767&#45;&gt;GO:0019362</title>
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<!-- GO:0006766&#45;&gt;GO:0006767 -->
<g id="edge175" class="edge"><title>GO:0006766&#45;&gt;GO:0006767</title>
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<!-- GO:0009117 -->
<g id="node86" class="node"><title>GO:0009117</title>
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<!-- GO:0009117&#45;&gt;GO:0019362 -->
<g id="edge179" class="edge"><title>GO:0009117&#45;&gt;GO:0019362</title>
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<!-- GO:0006753 -->
<g id="node87" class="node"><title>GO:0006753</title>
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<text text-anchor="middle" x="2259" y="-463.667" style="font-family:Arial;font-size:10px;">nucleoside phosphate</text>
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<!-- GO:0006753&#45;&gt;GO:0009117 -->
<g id="edge181" class="edge"><title>GO:0006753&#45;&gt;GO:0009117</title>
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<!-- GO:0055086 -->
<g id="node88" class="node"><title>GO:0055086</title>
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<text text-anchor="middle" x="2266" y="-559.667" style="font-family:Arial;font-size:10px;">nucleobase,</text>
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<text text-anchor="middle" x="2266" y="-535.667" style="font-family:Arial;font-size:10px;">nucleotide metabolic</text>
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<!-- GO:0055086&#45;&gt;GO:0006753 -->
<g id="edge183" class="edge"><title>GO:0055086&#45;&gt;GO:0006753</title>
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<!-- GO:0006139&#45;&gt;GO:0055086 -->
<g id="edge185" class="edge"><title>GO:0006139&#45;&gt;GO:0055086</title>
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<!-- GO:0019674&#45;&gt;GO:0006116 -->
<g id="edge191" class="edge"><title>GO:0019674&#45;&gt;GO:0006116</title>
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<!-- GO:0031960&#45;&gt;GO:0051384 -->
<g id="edge199" class="edge"><title>GO:0031960&#45;&gt;GO:0051384</title>
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<text text-anchor="middle" x="1466" y="-627.667" style="font-family:Arial;font-size:10px;">steroid hormone</text>
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<!-- GO:0048545&#45;&gt;GO:0031960 -->
<g id="edge201" class="edge"><title>GO:0048545&#45;&gt;GO:0031960</title>
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<!-- GO:0009725&#45;&gt;GO:0043434 -->
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<!-- GO:0009725&#45;&gt;GO:0048545 -->
<g id="edge203" class="edge"><title>GO:0009725&#45;&gt;GO:0048545</title>
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<g id="edge205" class="edge"><title>GO:0009719&#45;&gt;GO:0009725</title>
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<!-- GO:0048029&#45;&gt;GO:0070061 -->
<g id="edge211" class="edge"><title>GO:0048029&#45;&gt;GO:0070061</title>
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<!-- GO:0005529&#45;&gt;GO:0048029 -->
<g id="edge213" class="edge"><title>GO:0005529&#45;&gt;GO:0048029</title>
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<!-- GO:0030246&#45;&gt;GO:0005529 -->
<g id="edge215" class="edge"><title>GO:0030246&#45;&gt;GO:0005529</title>
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<text text-anchor="middle" x="855" y="-289.667" style="font-family:Arial;font-size:10px;">part</text>
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<!-- GO:0044430&#45;&gt;GO:0005815 -->
<g id="edge221" class="edge"><title>GO:0044430&#45;&gt;GO:0005815</title>
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<g id="edge307" class="edge"><title>GO:0044430&#45;&gt;GO:0044450</title>
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<g id="edge223" class="edge"><title>GO:0044446&#45;&gt;GO:0044430</title>
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<!-- GO:0044422&#45;&gt;GO:0044446 -->
<g id="edge225" class="edge"><title>GO:0044422&#45;&gt;GO:0044446</title>
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<!-- GO:0005856&#45;&gt;GO:0044430 -->
<g id="edge235" class="edge"><title>GO:0005856&#45;&gt;GO:0044430</title>
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<text text-anchor="middle" x="949" y="-301.667" style="font-family:Arial;font-size:10px;">microtubule</text>
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<!-- GO:0005856&#45;&gt;GO:0015630 -->
<g id="edge249" class="edge"><title>GO:0005856&#45;&gt;GO:0015630</title>
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<!-- GO:0043232&#45;&gt;GO:0005856 -->
<g id="edge237" class="edge"><title>GO:0043232&#45;&gt;GO:0005856</title>
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<!-- GO:0043232&#45;&gt;GO:0005813 -->
<g id="edge317" class="edge"><title>GO:0043232&#45;&gt;GO:0005813</title>
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<!-- GO:0043228&#45;&gt;GO:0043232 -->
<g id="edge239" class="edge"><title>GO:0043228&#45;&gt;GO:0043232</title>
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<g id="edge247" class="edge"><title>GO:0015630&#45;&gt;GO:0005815</title>
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<!-- GO:0006006&#45;&gt;GO:0006094 -->
<g id="edge251" class="edge"><title>GO:0006006&#45;&gt;GO:0006094</title>
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<!-- GO:0006090 -->
<g id="node106" class="node"><title>GO:0006090</title>
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<!-- GO:0006090&#45;&gt;GO:0006094 -->
<g id="edge255" class="edge"><title>GO:0006090&#45;&gt;GO:0006094</title>
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<!-- GO:0032787&#45;&gt;GO:0006090 -->
<g id="edge257" class="edge"><title>GO:0032787&#45;&gt;GO:0006090</title>
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<g id="node108" class="node"><title>GO:0019752</title>
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<!-- GO:0019752&#45;&gt;GO:0032787 -->
<g id="edge259" class="edge"><title>GO:0019752&#45;&gt;GO:0032787</title>
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<!-- GO:0006082&#45;&gt;GO:0019752 -->
<g id="edge261" class="edge"><title>GO:0006082&#45;&gt;GO:0019752</title>
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<g id="edge265" class="edge"><title>GO:0019319&#45;&gt;GO:0006094</title>
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<g id="edge269" class="edge"><title>GO:0046364&#45;&gt;GO:0019319</title>
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<g id="edge273" class="edge"><title>GO:0034637&#45;&gt;GO:0046364</title>
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<g id="edge275" class="edge"><title>GO:0016051&#45;&gt;GO:0034637</title>
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<g id="edge279" class="edge"><title>GO:0009058&#45;&gt;GO:0016051</title>
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<g id="edge285" class="edge"><title>GO:0009058&#45;&gt;GO:0044249</title>
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<g id="edge293" class="edge"><title>GO:0044249&#45;&gt;GO:0046165</title>
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<g id="edge289" class="edge"><title>GO:0046165&#45;&gt;GO:0046364</title>
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<!-- GO:0016832&#45;&gt;GO:0004332 -->
<g id="edge295" class="edge"><title>GO:0016832&#45;&gt;GO:0004332</title>
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<g id="edge297" class="edge"><title>GO:0016830&#45;&gt;GO:0016832</title>
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<g id="edge299" class="edge"><title>GO:0016829&#45;&gt;GO:0016830</title>
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<g id="edge313" class="edge"><title>GO:0005813&#45;&gt;GO:0034451</title>
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