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<text text-anchor="middle" x="1854" y="-341.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
<polygon style="fill:lightblue;stroke:lightblue;" points="1807,-320 1807,-336 1901,-336 1901,-320 1807,-320"/>
<polygon style="fill:none;stroke:black;" points="1807,-320 1807,-336 1901,-336 1901,-320 1807,-320"/>
<text text-anchor="middle" x="1854" y="-325.667" style="font-family:Arial;font-size:10px;">Mouse</text>
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<!-- GO:0032438 -->
<g id="node11" class="node"><title>GO:0032438</title>
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<polygon style="fill:none;stroke:black;" points="1655,-359 1655,-375 1773,-375 1773,-359 1655,-359"/>
<text text-anchor="middle" x="1714" y="-364.667" style="font-family:Arial;font-size:10px;">melanosome organization</text>
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<polygon style="fill:none;stroke:black;" points="1655,-343 1655,-359 1773,-359 1773,-343 1655,-343"/>
<text text-anchor="middle" x="1714" y="-348.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
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<text text-anchor="middle" x="1714" y="-332.667" style="font-family:Arial;font-size:10px;">Mouse</text>
</g>
<!-- GO:0005515 -->
<g id="node12" class="node"><title>GO:0005515</title>
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<polygon style="fill:none;stroke:black;" points="17,-693 17,-709 87,-709 87,-693 17,-693"/>
<text text-anchor="middle" x="52" y="-698.667" style="font-family:Arial;font-size:10px;">protein binding</text>
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<polygon style="fill:none;stroke:black;" points="17,-677 17,-693 87,-693 87,-677 17,-677"/>
<text text-anchor="middle" x="52" y="-682.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
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<polygon style="fill:none;stroke:black;" points="17,-661 17,-677 87,-677 87,-661 17,-661"/>
<text text-anchor="middle" x="52" y="-666.667" style="font-family:Arial;font-size:10px;">Mouse</text>
</g>
<!-- GO:0005515&#45;&gt;GO:0042802 -->
<g id="edge47" class="edge"><title>GO:0005515&#45;&gt;GO:0042802</title>
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<polygon style="fill:gray;stroke:gray;" points="48.5001,-651 52,-661 55.5001,-651 48.5001,-651"/>
</g>
<!-- GO:0007596 -->
<g id="node13" class="node"><title>GO:0007596</title>
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<polygon style="fill:none;stroke:black;" points="985,-448 985,-464 1067,-464 1067,-448 985,-448"/>
<text text-anchor="middle" x="1026" y="-453.667" style="font-family:Arial;font-size:10px;">blood coagulation</text>
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<polygon style="fill:none;stroke:black;" points="985,-432 985,-448 1067,-448 1067,-432 985,-432"/>
<text text-anchor="middle" x="1026" y="-437.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
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<polygon style="fill:none;stroke:black;" points="985,-416 985,-432 1067,-432 1067,-416 985,-416"/>
<text text-anchor="middle" x="1026" y="-421.667" style="font-family:Arial;font-size:10px;">Mouse</text>
</g>
<!-- GO:0007596&#45;&gt;GO:0030168 -->
<g id="edge9" class="edge"><title>GO:0007596&#45;&gt;GO:0030168</title>
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<polygon style="fill:blue;stroke:blue;" points="1028.84,-405.406 1029,-416 1035.48,-407.62 1028.84,-405.406"/>
</g>
<!-- GO:0005829 -->
<g id="node14" class="node"><title>GO:0005829</title>
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<polygon style="fill:none;stroke:black;" points="196,-271 196,-287 262,-287 262,-271 196,-271"/>
<text text-anchor="middle" x="229" y="-276.667" style="font-family:Arial;font-size:10px;">cytosol</text>
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<polygon style="fill:none;stroke:black;" points="196,-255 196,-271 262,-271 262,-255 196,-255"/>
<text text-anchor="middle" x="229" y="-260.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
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<polygon style="fill:none;stroke:black;" points="196,-239 196,-255 262,-255 262,-239 196,-239"/>
<text text-anchor="middle" x="229" y="-244.667" style="font-family:Arial;font-size:10px;">Mouse</text>
</g>
<!-- GO:0044445 -->
<g id="node38" class="node"><title>GO:0044445</title>
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<polygon style="fill:none;stroke:black;" points="215,-161 215,-177 279,-177 279,-161 215,-161"/>
<text text-anchor="middle" x="247" y="-166.667" style="font-family:Arial;font-size:10px;">cytosolic part</text>
</g>
<!-- GO:0005829&#45;&gt;GO:0044445 -->
<g id="edge83" class="edge"><title>GO:0005829&#45;&gt;GO:0044445</title>
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<polygon style="fill:blue;stroke:blue;" points="229.529,-228.508 231,-239 236.393,-229.881 229.529,-228.508"/>
</g>
<!-- GO:0048066 -->
<g id="node15" class="node"><title>GO:0048066</title>
<polygon style="fill:white;stroke:white;" points="694,-686 694,-716 784,-716 784,-686 694,-686"/>
<polygon style="fill:none;stroke:black;" points="694,-686 694,-716 784,-716 784,-686 694,-686"/>
<text text-anchor="middle" x="739" y="-705.667" style="font-family:Arial;font-size:10px;">pigmentation</text>
<text text-anchor="middle" x="739" y="-693.667" style="font-family:Arial;font-size:10px;">during development</text>
<polygon style="fill:gold;stroke:gold;" points="694,-670 694,-686 784,-686 784,-670 694,-670"/>
<polygon style="fill:none;stroke:black;" points="694,-670 694,-686 784,-686 784,-670 694,-670"/>
<text text-anchor="middle" x="739" y="-675.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
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<polygon style="fill:none;stroke:black;" points="694,-654 694,-670 784,-670 784,-654 694,-654"/>
<text text-anchor="middle" x="739" y="-659.667" style="font-family:Arial;font-size:10px;">Mouse</text>
</g>
<!-- GO:0001654 -->
<g id="node16" class="node"><title>GO:0001654</title>
<polygon style="fill:white;stroke:white;" points="380,-359 380,-375 458,-375 458,-359 380,-359"/>
<polygon style="fill:none;stroke:black;" points="380,-359 380,-375 458,-375 458,-359 380,-359"/>
<text text-anchor="middle" x="419" y="-364.667" style="font-family:Arial;font-size:10px;">eye development</text>
<polygon style="fill:tomato;stroke:tomato;" points="380,-343 380,-359 458,-359 458,-343 380,-343"/>
<polygon style="fill:none;stroke:black;" points="380,-343 380,-359 458,-359 458,-343 380,-343"/>
<text text-anchor="middle" x="419" y="-348.667" style="font-family:Arial;font-size:10px;">Human</text>
<polygon style="fill:gold;stroke:gold;" points="380,-327 380,-343 458,-343 458,-327 380,-327"/>
<polygon style="fill:none;stroke:black;" points="380,-327 380,-343 458,-343 458,-327 380,-327"/>
<text text-anchor="middle" x="419" y="-332.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0033299 -->
<g id="node17" class="node"><title>GO:0033299</title>
<polygon style="fill:white;stroke:white;" points="1974,-264 1974,-294 2068,-294 2068,-264 1974,-264"/>
<polygon style="fill:none;stroke:black;" points="1974,-264 1974,-294 2068,-294 2068,-264 1974,-264"/>
<text text-anchor="middle" x="2021" y="-283.667" style="font-family:Arial;font-size:10px;">secretion of</text>
<text text-anchor="middle" x="2021" y="-271.667" style="font-family:Arial;font-size:10px;">lysosomal enzymes</text>
<polygon style="fill:gold;stroke:gold;" points="1974,-248 1974,-264 2068,-264 2068,-248 1974,-248"/>
<polygon style="fill:none;stroke:black;" points="1974,-248 1974,-264 2068,-264 2068,-248 1974,-248"/>
<text text-anchor="middle" x="2021" y="-253.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
<polygon style="fill:lightblue;stroke:lightblue;" points="1974,-232 1974,-248 2068,-248 2068,-232 1974,-232"/>
<polygon style="fill:none;stroke:black;" points="1974,-232 1974,-248 2068,-248 2068,-232 1974,-232"/>
<text text-anchor="middle" x="2021" y="-237.667" style="font-family:Arial;font-size:10px;">Mouse</text>
</g>
<!-- GO:0005737 -->
<g id="node18" class="node"><title>GO:0005737</title>
<polygon style="fill:white;stroke:white;" points="227,-456 227,-472 293,-472 293,-456 227,-456"/>
<polygon style="fill:none;stroke:black;" points="227,-456 227,-472 293,-472 293,-456 227,-456"/>
<text text-anchor="middle" x="260" y="-461.667" style="font-family:Arial;font-size:10px;">cytoplasm</text>
<polygon style="fill:tomato;stroke:tomato;" points="227,-440 227,-456 293,-456 293,-440 227,-440"/>
<polygon style="fill:none;stroke:black;" points="227,-440 227,-456 293,-456 293,-440 227,-440"/>
<text text-anchor="middle" x="260" y="-445.667" style="font-family:Arial;font-size:10px;">Human</text>
<polygon style="fill:gold;stroke:gold;" points="227,-424 227,-440 293,-440 293,-424 227,-424"/>
<polygon style="fill:none;stroke:black;" points="227,-424 227,-440 293,-440 293,-424 227,-424"/>
<text text-anchor="middle" x="260" y="-429.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
<polygon style="fill:lightblue;stroke:lightblue;" points="227,-408 227,-424 293,-424 293,-408 227,-408"/>
<polygon style="fill:none;stroke:black;" points="227,-408 227,-424 293,-424 293,-408 227,-408"/>
<text text-anchor="middle" x="260" y="-413.667" style="font-family:Arial;font-size:10px;">Mouse</text>
</g>
<!-- GO:0044444 -->
<g id="node39" class="node"><title>GO:0044444</title>
<polygon style="fill:white;stroke:white;" points="246,-336 246,-366 304,-366 304,-336 246,-336"/>
<polygon style="fill:none;stroke:black;" points="246,-336 246,-366 304,-366 304,-336 246,-336"/>
<text text-anchor="middle" x="275" y="-355.667" style="font-family:Arial;font-size:10px;">cytoplasmic</text>
<text text-anchor="middle" x="275" y="-343.667" style="font-family:Arial;font-size:10px;">part</text>
</g>
<!-- GO:0005737&#45;&gt;GO:0044444 -->
<g id="edge79" class="edge"><title>GO:0005737&#45;&gt;GO:0044444</title>
<path style="fill:none;stroke:blue;" d="M264,-398C267,-388 270,-376 272,-366"/>
<polygon style="fill:blue;stroke:blue;" points="260.529,-397.508 262,-408 267.393,-398.881 260.529,-397.508"/>
</g>
<!-- GO:0043473&#45;&gt;GO:0048066 -->
<g id="edge195" class="edge"><title>GO:0043473&#45;&gt;GO:0048066</title>
<path style="fill:none;stroke:gray;" d="M1142,-742C1132,-740 1121,-739 1111,-738 973,-722 936,-744 801,-720 795,-719 790,-717 784,-716"/>
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</g>
<!-- GO:0033059 -->
<g id="node66" class="node"><title>GO:0033059</title>
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<polygon style="fill:none;stroke:black;" points="1520,-677 1520,-693 1616,-693 1616,-677 1520,-677"/>
<text text-anchor="middle" x="1568" y="-682.667" style="font-family:Arial;font-size:10px;">cellular pigmentation</text>
</g>
<!-- GO:0043473&#45;&gt;GO:0033059 -->
<g id="edge187" class="edge"><title>GO:0043473&#45;&gt;GO:0033059</title>
<path style="fill:none;stroke:gray;" d="M1228,-744C1242,-742 1259,-740 1273,-738 1341,-729 1359,-732 1427,-720 1466,-713 1511,-701 1539,-693"/>
<polygon style="fill:gray;stroke:gray;" points="1227.6,-740.522 1218,-745 1228.3,-747.488 1227.6,-740.522"/>
</g>
<!-- GO:0001775 -->
<g id="node20" class="node"><title>GO:0001775</title>
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<polygon style="fill:none;stroke:black;" points="1364,-589 1364,-605 1428,-605 1428,-589 1364,-589"/>
<text text-anchor="middle" x="1396" y="-594.667" style="font-family:Arial;font-size:10px;">cell activation</text>
</g>
<!-- GO:0001775&#45;&gt;GO:0030168 -->
<g id="edge3" class="edge"><title>GO:0001775&#45;&gt;GO:0030168</title>
<path style="fill:none;stroke:gray;" d="M1370,-585C1353,-577 1330,-568 1309,-562 1258,-548 1237,-570 1192,-544 1124,-504 1136,-462 1084,-404 1075,-393 1063,-382 1055,-375"/>
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</g>
<!-- GO:0050865 -->
<g id="node50" class="node"><title>GO:0050865</title>
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<polygon style="fill:none;stroke:black;" points="1455,-504 1455,-534 1519,-534 1519,-504 1455,-504"/>
<text text-anchor="middle" x="1487" y="-523.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="1487" y="-511.667" style="font-family:Arial;font-size:10px;">cell activation</text>
</g>
<!-- GO:0001775&#45;&gt;GO:0050865 -->
<g id="edge113" class="edge"><title>GO:0001775&#45;&gt;GO:0050865</title>
<path style="fill:none;stroke:black;" d="M1413,-582C1429,-569 1453,-548 1469,-534"/>
<polygon style="fill:black;stroke:black;" points="1410.22,-579.781 1405,-589 1414.83,-585.049 1410.22,-579.781"/>
</g>
<!-- GO:0045321 -->
<g id="node52" class="node"><title>GO:0045321</title>
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<polygon style="fill:none;stroke:black;" points="1209,-511 1209,-527 1301,-527 1301,-511 1209,-511"/>
<text text-anchor="middle" x="1255" y="-516.667" style="font-family:Arial;font-size:10px;">leukocyte activation</text>
</g>
<!-- GO:0001775&#45;&gt;GO:0045321 -->
<g id="edge117" class="edge"><title>GO:0001775&#45;&gt;GO:0045321</title>
<path style="fill:none;stroke:gray;" d="M1372,-584C1343,-568 1294,-540 1270,-527"/>
<polygon style="fill:gray;stroke:gray;" points="1370.56,-587.203 1381,-589 1373.96,-581.084 1370.56,-587.203"/>
</g>
<!-- GO:0050867 -->
<g id="node59" class="node"><title>GO:0050867</title>
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<polygon style="fill:none;stroke:black;" points="1527,-425 1527,-455 1611,-455 1611,-425 1527,-425"/>
<text text-anchor="middle" x="1569" y="-444.667" style="font-family:Arial;font-size:10px;">positive regulation</text>
<text text-anchor="middle" x="1569" y="-432.667" style="font-family:Arial;font-size:10px;">of cell activation</text>
</g>
<!-- GO:0001775&#45;&gt;GO:0050867 -->
<g id="edge159" class="edge"><title>GO:0001775&#45;&gt;GO:0050867</title>
<path style="fill:none;stroke:forestgreen;" d="M1413,-582C1422,-575 1433,-567 1445,-562 1482,-545 1505,-571 1536,-544 1562,-521 1567,-478 1569,-455"/>
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<!-- GO:0009987&#45;&gt;GO:0001775 -->
<g id="edge5" class="edge"><title>GO:0009987&#45;&gt;GO:0001775</title>
<path style="fill:none;stroke:gray;" d="M1605,-758C1574,-751 1534,-740 1503,-720 1454,-688 1414,-627 1401,-605"/>
<polygon style="fill:gray;stroke:gray;" points="1604.51,-761.471 1615,-760 1605.88,-754.607 1604.51,-761.471"/>
</g>
<!-- GO:0050794 -->
<g id="node51" class="node"><title>GO:0050794</title>
<polygon style="fill:white;stroke:white;" points="1580,-582 1580,-612 1654,-612 1654,-582 1580,-582"/>
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<text text-anchor="middle" x="1617" y="-601.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="1617" y="-589.667" style="font-family:Arial;font-size:10px;">cellular process</text>
</g>
<!-- GO:0009987&#45;&gt;GO:0050794 -->
<g id="edge111" class="edge"><title>GO:0009987&#45;&gt;GO:0050794</title>
<path style="fill:none;stroke:black;" d="M1650,-748C1646,-725 1641,-683 1633,-650 1630,-637 1625,-623 1622,-612"/>
<polygon style="fill:black;stroke:black;" points="1646.52,-748.398 1651,-758 1653.49,-747.701 1646.52,-748.398"/>
</g>
<!-- GO:0048522 -->
<g id="node60" class="node"><title>GO:0048522</title>
<polygon style="fill:white;stroke:white;" points="1591,-498 1591,-540 1675,-540 1675,-498 1591,-498"/>
<polygon style="fill:none;stroke:black;" points="1591,-498 1591,-540 1675,-540 1675,-498 1591,-498"/>
<text text-anchor="middle" x="1633" y="-529.667" style="font-family:Arial;font-size:10px;">positive regulation</text>
<text text-anchor="middle" x="1633" y="-517.667" style="font-family:Arial;font-size:10px;">of cellular</text>
<text text-anchor="middle" x="1633" y="-505.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0009987&#45;&gt;GO:0048522 -->
<g id="edge155" class="edge"><title>GO:0009987&#45;&gt;GO:0048522</title>
<path style="fill:none;stroke:forestgreen;" d="M1659,-748C1671,-712 1695,-627 1671,-562 1668,-554 1662,-546 1657,-540"/>
<polygon style="fill:forestgreen;stroke:forestgreen;" points="1655.46,-747.415 1655,-758 1661.96,-750.015 1655.46,-747.415"/>
</g>
<!-- GO:0016043 -->
<g id="node64" class="node"><title>GO:0016043</title>
<polygon style="fill:white;stroke:white;" points="1731,-670 1731,-700 1819,-700 1819,-670 1731,-670"/>
<polygon style="fill:none;stroke:black;" points="1731,-670 1731,-700 1819,-700 1819,-670 1731,-670"/>
<text text-anchor="middle" x="1775" y="-689.667" style="font-family:Arial;font-size:10px;">cellular component</text>
<text text-anchor="middle" x="1775" y="-677.667" style="font-family:Arial;font-size:10px;">organization</text>
</g>
<!-- GO:0009987&#45;&gt;GO:0016043 -->
<g id="edge177" class="edge"><title>GO:0009987&#45;&gt;GO:0016043</title>
<path style="fill:none;stroke:gray;" d="M1672,-752C1694,-737 1729,-715 1752,-700"/>
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</g>
<!-- GO:0009987&#45;&gt;GO:0033059 -->
<g id="edge185" class="edge"><title>GO:0009987&#45;&gt;GO:0033059</title>
<path style="fill:none;stroke:gray;" d="M1637,-751C1619,-734 1591,-707 1577,-693"/>
<polygon style="fill:gray;stroke:gray;" points="1634.45,-753.404 1644,-758 1639.4,-748.454 1634.45,-753.404"/>
</g>
<!-- GO:0051641 -->
<g id="node84" class="node"><title>GO:0051641</title>
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<polygon style="fill:none;stroke:black;" points="1857,-677 1857,-693 1945,-693 1945,-677 1857,-677"/>
<text text-anchor="middle" x="1901" y="-682.667" style="font-family:Arial;font-size:10px;">cellular localization</text>
</g>
<!-- GO:0009987&#45;&gt;GO:0051641 -->
<g id="edge251" class="edge"><title>GO:0009987&#45;&gt;GO:0051641</title>
<path style="fill:none;stroke:gray;" d="M1699,-757C1737,-750 1790,-737 1836,-720 1855,-713 1875,-701 1888,-693"/>
<polygon style="fill:gray;stroke:gray;" points="1698.12,-753.607 1689,-759 1699.49,-760.471 1698.12,-753.607"/>
</g>
<!-- GO:0007599 -->
<g id="node22" class="node"><title>GO:0007599</title>
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<polygon style="fill:none;stroke:black;" points="1043,-511 1043,-527 1099,-527 1099,-511 1043,-511"/>
<text text-anchor="middle" x="1071" y="-516.667" style="font-family:Arial;font-size:10px;">hemostasis</text>
</g>
<!-- GO:0007599&#45;&gt;GO:0007596 -->
<g id="edge11" class="edge"><title>GO:0007599&#45;&gt;GO:0007596</title>
<path style="fill:none;stroke:gray;" d="M1059,-503C1050,-490 1038,-474 1032,-464"/>
<polygon style="fill:gray;stroke:gray;" points="1056.2,-505.1 1065,-511 1061.8,-500.9 1056.2,-505.1"/>
</g>
<!-- GO:0050878 -->
<g id="node23" class="node"><title>GO:0050878</title>
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<g id="edge13" class="edge"><title>GO:0050878&#45;&gt;GO:0007599</title>
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<g id="edge27" class="edge"><title>GO:0032501&#45;&gt;GO:0050817</title>
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<!-- GO:0032501&#45;&gt;GO:0007275 -->
<g id="edge211" class="edge"><title>GO:0032501&#45;&gt;GO:0007275</title>
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<g id="edge19" class="edge"><title>GO:0065008&#45;&gt;GO:0050878</title>
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<!-- GO:0042060&#45;&gt;GO:0007596 -->
<g id="edge29" class="edge"><title>GO:0042060&#45;&gt;GO:0007596</title>
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<g id="edge31" class="edge"><title>GO:0009611&#45;&gt;GO:0042060</title>
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<g id="edge33" class="edge"><title>GO:0006950&#45;&gt;GO:0009611</title>
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<g id="edge35" class="edge"><title>GO:0050896&#45;&gt;GO:0006950</title>
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<text text-anchor="middle" x="620" y="-677.667" style="font-family:Arial;font-size:10px;">external stimulus</text>
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<!-- GO:0050896&#45;&gt;GO:0009605 -->
<g id="edge41" class="edge"><title>GO:0050896&#45;&gt;GO:0009605</title>
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<text text-anchor="middle" x="952" y="-677.667" style="font-family:Arial;font-size:10px;">chemical stimulus</text>
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<!-- GO:0050896&#45;&gt;GO:0042221 -->
<g id="edge45" class="edge"><title>GO:0050896&#45;&gt;GO:0042221</title>
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<!-- GO:0009605&#45;&gt;GO:0009611 -->
<g id="edge39" class="edge"><title>GO:0009605&#45;&gt;GO:0009611</title>
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<g id="edge43" class="edge"><title>GO:0042221&#45;&gt;GO:0042493</title>
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<g id="edge49" class="edge"><title>GO:0005488&#45;&gt;GO:0005515</title>
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<!-- GO:0031082&#45;&gt;GO:0031083 -->
<g id="edge53" class="edge"><title>GO:0031082&#45;&gt;GO:0031083</title>
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<!-- GO:0043234&#45;&gt;GO:0031082 -->
<g id="edge55" class="edge"><title>GO:0043234&#45;&gt;GO:0031082</title>
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<g id="edge57" class="edge"><title>GO:0032991&#45;&gt;GO:0043234</title>
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<g id="edge61" class="edge"><title>GO:0044445&#45;&gt;GO:0031082</title>
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<g id="edge85" class="edge"><title>GO:0044444&#45;&gt;GO:0005829</title>
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<g id="edge63" class="edge"><title>GO:0044444&#45;&gt;GO:0044445</title>
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<!-- GO:0044424&#45;&gt;GO:0005737 -->
<g id="edge81" class="edge"><title>GO:0044424&#45;&gt;GO:0005737</title>
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<g id="edge65" class="edge"><title>GO:0044424&#45;&gt;GO:0044444</title>
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<!-- GO:0044464&#45;&gt;GO:0005622 -->
<g id="edge77" class="edge"><title>GO:0044464&#45;&gt;GO:0005622</title>
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<g id="edge71" class="edge"><title>GO:0005623&#45;&gt;GO:0044464</title>
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<g id="edge75" class="edge"><title>GO:0005622&#45;&gt;GO:0044424</title>
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<!-- GO:0032814&#45;&gt;GO:0032816 -->
<g id="edge87" class="edge"><title>GO:0032814&#45;&gt;GO:0032816</title>
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<text text-anchor="middle" x="1308" y="-355.667" style="font-family:Arial;font-size:10px;">regulation of</text>
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<!-- GO:0051249&#45;&gt;GO:0032814 -->
<g id="edge89" class="edge"><title>GO:0051249&#45;&gt;GO:0032814</title>
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<!-- GO:0051249&#45;&gt;GO:0051251 -->
<g id="edge163" class="edge"><title>GO:0051249&#45;&gt;GO:0051251</title>
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<g id="edge91" class="edge"><title>GO:0002694&#45;&gt;GO:0051249</title>
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<g id="edge145" class="edge"><title>GO:0002694&#45;&gt;GO:0002696</title>
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<g id="edge93" class="edge"><title>GO:0002682&#45;&gt;GO:0002694</title>
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<g id="edge135" class="edge"><title>GO:0002682&#45;&gt;GO:0002684</title>
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<g id="edge107" class="edge"><title>GO:0050794&#45;&gt;GO:0050865</title>
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<g id="edge153" class="edge"><title>GO:0050794&#45;&gt;GO:0048522</title>
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<g id="edge115" class="edge"><title>GO:0045321&#45;&gt;GO:0002694</title>
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<g id="node53" class="node"><title>GO:0046649</title>
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<g id="edge123" class="edge"><title>GO:0045321&#45;&gt;GO:0046649</title>
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<g id="edge161" class="edge"><title>GO:0045321&#45;&gt;GO:0002696</title>
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<g id="edge121" class="edge"><title>GO:0046649&#45;&gt;GO:0051249</title>
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<g id="edge127" class="edge"><title>GO:0046649&#45;&gt;GO:0030101</title>
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<g id="edge131" class="edge"><title>GO:0002696&#45;&gt;GO:0051251</title>
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<g id="edge133" class="edge"><title>GO:0002684&#45;&gt;GO:0002696</title>
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<g id="edge151" class="edge"><title>GO:0048518&#45;&gt;GO:0048522</title>
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<g id="edge147" class="edge"><title>GO:0050867&#45;&gt;GO:0002696</title>
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<g id="edge149" class="edge"><title>GO:0048522&#45;&gt;GO:0050867</title>
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<g id="edge169" class="edge"><title>GO:0033363&#45;&gt;GO:0060155</title>
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<g id="edge173" class="edge"><title>GO:0006996&#45;&gt;GO:0016050</title>
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<!-- GO:0009306&#45;&gt;GO:0033299 -->
<g id="edge215" class="edge"><title>GO:0009306&#45;&gt;GO:0033299</title>
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<polygon style="fill:none;stroke:black;" points="2018,-432 2018,-448 2094,-448 2094,-432 2018,-432"/>
<text text-anchor="middle" x="2056" y="-437.667" style="font-family:Arial;font-size:10px;">protein transport</text>
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<!-- GO:0015031&#45;&gt;GO:0009306 -->
<g id="edge217" class="edge"><title>GO:0015031&#45;&gt;GO:0009306</title>
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<polygon style="fill:none;stroke:black;" points="1998,-589 1998,-605 2042,-605 2042,-589 1998,-589"/>
<text text-anchor="middle" x="2020" y="-594.667" style="font-family:Arial;font-size:10px;">transport</text>
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<!-- GO:0006810&#45;&gt;GO:0015031 -->
<g id="edge219" class="edge"><title>GO:0006810&#45;&gt;GO:0015031</title>
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<g id="edge243" class="edge"><title>GO:0006810&#45;&gt;GO:0046903</title>
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<g id="edge221" class="edge"><title>GO:0051234&#45;&gt;GO:0006810</title>
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<text text-anchor="middle" x="2134" y="-511.667" style="font-family:Arial;font-size:10px;">of protein localization</text>
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<g id="edge231" class="edge"><title>GO:0051234&#45;&gt;GO:0045184</title>
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<g id="edge247" class="edge"><title>GO:0051234&#45;&gt;GO:0051649</title>
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<g id="edge225" class="edge"><title>GO:0051179&#45;&gt;GO:0051234</title>
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<text text-anchor="middle" x="2141" y="-689.667" style="font-family:Arial;font-size:10px;">macromolecule</text>
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<g id="edge229" class="edge"><title>GO:0045184&#45;&gt;GO:0015031</title>
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<g id="edge233" class="edge"><title>GO:0008104&#45;&gt;GO:0045184</title>
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<g id="edge235" class="edge"><title>GO:0033036&#45;&gt;GO:0008104</title>
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<g id="node81" class="node"><title>GO:0032940</title>
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<!-- GO:0032940&#45;&gt;GO:0009306 -->
<g id="edge239" class="edge"><title>GO:0032940&#45;&gt;GO:0009306</title>
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<!-- GO:0046903&#45;&gt;GO:0032940 -->
<g id="edge241" class="edge"><title>GO:0046903&#45;&gt;GO:0032940</title>
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<g id="edge245" class="edge"><title>GO:0051649&#45;&gt;GO:0032940</title>
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<g id="edge249" class="edge"><title>GO:0051641&#45;&gt;GO:0051649</title>
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