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<text text-anchor="middle" x="1390" y="-617.667" style="font-family:Arial;font-size:10px;">Worm</text>
</g>
<!-- GO:0015629 -->
<g id="node6" class="node"><title>GO:0015629</title>
<polygon style="fill:white;stroke:white;" points="548,-372 548,-388 634,-388 634,-372 548,-372"/>
<polygon style="fill:none;stroke:black;" points="548,-372 548,-388 634,-388 634,-372 548,-372"/>
<text text-anchor="middle" x="591" y="-377.667" style="font-family:Arial;font-size:10px;">actin cytoskeleton</text>
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<polygon style="fill:none;stroke:black;" points="548,-356 548,-372 634,-372 634,-356 548,-356"/>
<text text-anchor="middle" x="591" y="-361.667" style="font-family:Arial;font-size:10px;">Human</text>
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<polygon style="fill:none;stroke:black;" points="548,-340 548,-356 634,-356 634,-340 548,-340"/>
<text text-anchor="middle" x="591" y="-345.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0006000 -->
<g id="node7" class="node"><title>GO:0006000</title>
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<polygon style="fill:none;stroke:black;" points="2515,-343 2515,-385 2601,-385 2601,-343 2515,-343"/>
<text text-anchor="middle" x="2558" y="-374.667" style="font-family:Arial;font-size:10px;">fructose metabolic</text>
<text text-anchor="middle" x="2558" y="-362.667" style="font-family:Arial;font-size:10px;">process</text>
<text text-anchor="middle" x="2558" y="-350.667" style="font-family:Arial;font-size:10px;">Dicty: ISS_only</text>
</g>
<!-- GO:0030388 -->
<g id="node27" class="node"><title>GO:0030388</title>
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<polygon style="fill:none;stroke:black;" points="2563,-284 2563,-314 2681,-314 2681,-284 2563,-284"/>
<text text-anchor="middle" x="2622" y="-303.667" style="font-family:Arial;font-size:10px;">fructose 1,6&#45;bisphosphate</text>
<text text-anchor="middle" x="2622" y="-291.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<polygon style="fill:none;stroke:black;" points="2563,-268 2563,-284 2681,-284 2681,-268 2563,-268"/>
<text text-anchor="middle" x="2622" y="-273.667" style="font-family:Arial;font-size:10px;">Human</text>
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<polygon style="fill:none;stroke:black;" points="2563,-252 2563,-268 2681,-268 2681,-252 2563,-252"/>
<text text-anchor="middle" x="2622" y="-257.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0006000&#45;&gt;GO:0030388 -->
<g id="edge457" class="edge"><title>GO:0006000&#45;&gt;GO:0030388</title>
<path style="fill:none;stroke:gray;" d="M2587,-335C2594,-328 2601,-321 2607,-314"/>
<polygon style="fill:gray;stroke:gray;" points="2583.6,-333.454 2579,-343 2588.55,-338.404 2583.6,-333.454"/>
</g>
<!-- GO:0046716 -->
<g id="node8" class="node"><title>GO:0046716</title>
<polygon style="fill:white;stroke:white;" points="3262,-633 3262,-649 3358,-649 3358,-633 3262,-633"/>
<polygon style="fill:none;stroke:black;" points="3262,-633 3262,-649 3358,-649 3358,-633 3262,-633"/>
<text text-anchor="middle" x="3310" y="-638.667" style="font-family:Arial;font-size:10px;">muscle maintenance</text>
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<polygon style="fill:none;stroke:black;" points="3262,-617 3262,-633 3358,-633 3358,-617 3262,-617"/>
<text text-anchor="middle" x="3310" y="-622.667" style="font-family:Arial;font-size:10px;">Human</text>
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<polygon style="fill:none;stroke:black;" points="3262,-601 3262,-617 3358,-617 3358,-601 3262,-601"/>
<text text-anchor="middle" x="3310" y="-606.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0006754 -->
<g id="node9" class="node"><title>GO:0006754</title>
<polygon style="fill:white;stroke:white;" points="2097,-36 2097,-66 2177,-66 2177,-36 2097,-36"/>
<polygon style="fill:none;stroke:black;" points="2097,-36 2097,-66 2177,-66 2177,-36 2097,-36"/>
<text text-anchor="middle" x="2137" y="-55.6667" style="font-family:Arial;font-size:10px;">ATP biosynthetic</text>
<text text-anchor="middle" x="2137" y="-43.6667" style="font-family:Arial;font-size:10px;">process</text>
<polygon style="fill:tomato;stroke:tomato;" points="2097,-20 2097,-36 2177,-36 2177,-20 2097,-20"/>
<polygon style="fill:none;stroke:black;" points="2097,-20 2097,-36 2177,-36 2177,-20 2097,-20"/>
<text text-anchor="middle" x="2137" y="-25.6667" style="font-family:Arial;font-size:10px;">Human</text>
<polygon style="fill:gold;stroke:gold;" points="2097,-4 2097,-20 2177,-20 2177,-4 2097,-4"/>
<polygon style="fill:none;stroke:black;" points="2097,-4 2097,-20 2177,-20 2177,-4 2097,-4"/>
<text text-anchor="middle" x="2137" y="-9.66667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0042802 -->
<g id="node10" class="node"><title>GO:0042802</title>
<polygon style="fill:goldenrod;stroke:goldenrod;" points="8,-804 8,-846 82,-846 82,-804 8,-804"/>
<polygon style="fill:none;stroke:black;" points="8,-804 8,-846 82,-846 82,-804 8,-804"/>
<text text-anchor="middle" x="45" y="-835.667" style="font-family:Arial;font-size:10px;">identical protein</text>
<text text-anchor="middle" x="45" y="-823.667" style="font-family:Arial;font-size:10px;">binding</text>
<text text-anchor="middle" x="45" y="-811.667" style="font-family:Arial;font-size:10px;">Worm</text>
</g>
<!-- GO:0048046 -->
<g id="node11" class="node"><title>GO:0048046</title>
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<polygon style="fill:none;stroke:black;" points="510,-878 510,-908 552,-908 552,-878 510,-878"/>
<text text-anchor="middle" x="531" y="-897.667" style="font-family:Arial;font-size:10px;">apoplast</text>
<text text-anchor="middle" x="531" y="-885.667" style="font-family:Arial;font-size:10px;">Dicot</text>
</g>
<!-- GO:0008360 -->
<g id="node12" class="node"><title>GO:0008360</title>
<polygon style="fill:white;stroke:white;" points="3471,-446 3471,-476 3537,-476 3537,-446 3471,-446"/>
<polygon style="fill:none;stroke:black;" points="3471,-446 3471,-476 3537,-476 3537,-446 3471,-446"/>
<text text-anchor="middle" x="3504" y="-465.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="3504" y="-453.667" style="font-family:Arial;font-size:10px;">cell shape</text>
<polygon style="fill:tomato;stroke:tomato;" points="3471,-430 3471,-446 3537,-446 3537,-430 3471,-430"/>
<polygon style="fill:none;stroke:black;" points="3471,-430 3471,-446 3537,-446 3537,-430 3471,-430"/>
<text text-anchor="middle" x="3504" y="-435.667" style="font-family:Arial;font-size:10px;">Human</text>
<polygon style="fill:gold;stroke:gold;" points="3471,-414 3471,-430 3537,-430 3537,-414 3471,-414"/>
<polygon style="fill:none;stroke:black;" points="3471,-414 3471,-430 3537,-430 3537,-414 3471,-414"/>
<text text-anchor="middle" x="3504" y="-419.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0005618 -->
<g id="node13" class="node"><title>GO:0005618</title>
<polygon style="fill:yellowgreen;stroke:yellowgreen;" points="998,-724 998,-754 1038,-754 1038,-724 998,-724"/>
<polygon style="fill:none;stroke:black;" points="998,-724 998,-754 1038,-754 1038,-724 998,-724"/>
<text text-anchor="middle" x="1018" y="-743.667" style="font-family:Arial;font-size:10px;">cell wall</text>
<text text-anchor="middle" x="1018" y="-731.667" style="font-family:Arial;font-size:10px;">Dicot</text>
</g>
<!-- GO:0009792 -->
<g id="node14" class="node"><title>GO:0009792</title>
<polygon style="fill:goldenrod;stroke:goldenrod;" points="3741,-712 3741,-766 3849,-766 3849,-712 3741,-712"/>
<polygon style="fill:none;stroke:black;" points="3741,-712 3741,-766 3849,-766 3849,-712 3741,-712"/>
<text text-anchor="middle" x="3795" y="-755.667" style="font-family:Arial;font-size:10px;">embryonic development</text>
<text text-anchor="middle" x="3795" y="-743.667" style="font-family:Arial;font-size:10px;">ending in birth</text>
<text text-anchor="middle" x="3795" y="-731.667" style="font-family:Arial;font-size:10px;">or egg hatching</text>
<text text-anchor="middle" x="3795" y="-719.667" style="font-family:Arial;font-size:10px;">Worm</text>
</g>
<!-- GO:0006941 -->
<g id="node15" class="node"><title>GO:0006941</title>
<polygon style="fill:white;stroke:white;" points="1200,-626 1200,-656 1272,-656 1272,-626 1200,-626"/>
<polygon style="fill:none;stroke:black;" points="1200,-626 1200,-656 1272,-656 1272,-626 1200,-626"/>
<text text-anchor="middle" x="1236" y="-645.667" style="font-family:Arial;font-size:10px;">striated muscle</text>
<text text-anchor="middle" x="1236" y="-633.667" style="font-family:Arial;font-size:10px;">contraction</text>
<polygon style="fill:tomato;stroke:tomato;" points="1200,-610 1200,-626 1272,-626 1272,-610 1200,-610"/>
<polygon style="fill:none;stroke:black;" points="1200,-610 1200,-626 1272,-626 1272,-610 1200,-610"/>
<text text-anchor="middle" x="1236" y="-615.667" style="font-family:Arial;font-size:10px;">Human</text>
<polygon style="fill:gold;stroke:gold;" points="1200,-594 1200,-610 1272,-610 1272,-594 1200,-594"/>
<polygon style="fill:none;stroke:black;" points="1200,-594 1200,-610 1272,-610 1272,-594 1200,-594"/>
<text text-anchor="middle" x="1236" y="-599.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0032496 -->
<g id="node16" class="node"><title>GO:0032496</title>
<polygon style="fill:gold;stroke:gold;" points="2186,-502 2186,-544 2272,-544 2272,-502 2186,-502"/>
<polygon style="fill:none;stroke:black;" points="2186,-502 2186,-544 2272,-544 2272,-502 2186,-502"/>
<text text-anchor="middle" x="2229" y="-533.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="2229" y="-521.667" style="font-family:Arial;font-size:10px;">lipopolysaccharide</text>
<text text-anchor="middle" x="2229" y="-509.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0006096 -->
<g id="node17" class="node"><title>GO:0006096</title>
<polygon style="fill:white;stroke:white;" points="2580,-207 2580,-223 2654,-223 2654,-207 2580,-207"/>
<polygon style="fill:none;stroke:black;" points="2580,-207 2580,-223 2654,-223 2654,-207 2580,-207"/>
<text text-anchor="middle" x="2617" y="-212.667" style="font-family:Arial;font-size:10px;">glycolysis</text>
<polygon style="fill:darkorange;stroke:darkorange;" points="2580,-191 2580,-207 2654,-207 2654,-191 2580,-191"/>
<polygon style="fill:none;stroke:black;" points="2580,-191 2580,-207 2654,-207 2654,-191 2580,-191"/>
<text text-anchor="middle" x="2617" y="-196.667" style="font-family:Arial;font-size:10px;">Dicty: ISS_only</text>
<polygon style="fill:darkturquoise;stroke:darkturquoise;" points="2580,-175 2580,-191 2654,-191 2654,-175 2580,-175"/>
<polygon style="fill:none;stroke:black;" points="2580,-175 2580,-191 2654,-191 2654,-175 2580,-175"/>
<text text-anchor="middle" x="2617" y="-180.667" style="font-family:Arial;font-size:10px;">Fly</text>
</g>
<!-- GO:0009507 -->
<g id="node18" class="node"><title>GO:0009507</title>
<polygon style="fill:yellowgreen;stroke:yellowgreen;" points="898,-349 898,-379 952,-379 952,-349 898,-349"/>
<polygon style="fill:none;stroke:black;" points="898,-349 898,-379 952,-379 952,-349 898,-349"/>
<text text-anchor="middle" x="925" y="-368.667" style="font-family:Arial;font-size:10px;">chloroplast</text>
<text text-anchor="middle" x="925" y="-356.667" style="font-family:Arial;font-size:10px;">Dicot</text>
</g>
<!-- GO:0005730 -->
<g id="node19" class="node"><title>GO:0005730</title>
<polygon style="fill:yellowgreen;stroke:yellowgreen;" points="747,-184 747,-214 795,-214 795,-184 747,-184"/>
<polygon style="fill:none;stroke:black;" points="747,-184 747,-214 795,-214 795,-184 747,-184"/>
<text text-anchor="middle" x="771" y="-203.667" style="font-family:Arial;font-size:10px;">nucleolus</text>
<text text-anchor="middle" x="771" y="-191.667" style="font-family:Arial;font-size:10px;">Dicot</text>
</g>
<!-- GO:0046686 -->
<g id="node20" class="node"><title>GO:0046686</title>
<polygon style="fill:yellowgreen;stroke:yellowgreen;" points="1791,-604 1791,-646 1853,-646 1853,-604 1791,-604"/>
<polygon style="fill:none;stroke:black;" points="1791,-604 1791,-646 1853,-646 1853,-604 1791,-604"/>
<text text-anchor="middle" x="1822" y="-635.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1822" y="-623.667" style="font-family:Arial;font-size:10px;">cadmium ion</text>
<text text-anchor="middle" x="1822" y="-611.667" style="font-family:Arial;font-size:10px;">Dicot</text>
</g>
<!-- GO:0016020 -->
<g id="node21" class="node"><title>GO:0016020</title>
<polygon style="fill:yellowgreen;stroke:yellowgreen;" points="856,-810 856,-840 908,-840 908,-810 856,-810"/>
<polygon style="fill:none;stroke:black;" points="856,-810 856,-840 908,-840 908,-810 856,-810"/>
<text text-anchor="middle" x="882" y="-829.667" style="font-family:Arial;font-size:10px;">membrane</text>
<text text-anchor="middle" x="882" y="-817.667" style="font-family:Arial;font-size:10px;">Dicot</text>
</g>
<!-- GO:0005886 -->
<g id="node22" class="node"><title>GO:0005886</title>
<polygon style="fill:yellowgreen;stroke:yellowgreen;" points="878,-724 878,-754 964,-754 964,-724 878,-724"/>
<polygon style="fill:none;stroke:black;" points="878,-724 878,-754 964,-754 964,-724 878,-724"/>
<text text-anchor="middle" x="921" y="-743.667" style="font-family:Arial;font-size:10px;">plasma membrane</text>
<text text-anchor="middle" x="921" y="-731.667" style="font-family:Arial;font-size:10px;">Dicot</text>
</g>
<!-- GO:0016020&#45;&gt;GO:0005886 -->
<g id="edge409" class="edge"><title>GO:0016020&#45;&gt;GO:0005886</title>
<path style="fill:none;stroke:gray;" d="M893,-801C900,-786 908,-767 914,-754"/>
<polygon style="fill:gray;stroke:gray;" points="889.863,-799.44 889,-810 896.26,-802.283 889.863,-799.44"/>
</g>
<!-- GO:0019861 -->
<g id="node23" class="node"><title>GO:0019861</title>
<polygon style="fill:white;stroke:white;" points="638,-747 638,-763 704,-763 704,-747 638,-747"/>
<polygon style="fill:none;stroke:black;" points="638,-747 638,-763 704,-763 704,-747 638,-747"/>
<text text-anchor="middle" x="671" y="-752.667" style="font-family:Arial;font-size:10px;">flagellum</text>
<polygon style="fill:gold;stroke:gold;" points="638,-731 638,-747 704,-747 704,-731 638,-731"/>
<polygon style="fill:none;stroke:black;" points="638,-731 638,-747 704,-747 704,-731 638,-731"/>
<text text-anchor="middle" x="671" y="-736.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
<polygon style="fill:lightblue;stroke:lightblue;" points="638,-715 638,-731 704,-731 704,-715 638,-715"/>
<polygon style="fill:none;stroke:black;" points="638,-715 638,-731 704,-731 704,-715 638,-715"/>
<text text-anchor="middle" x="671" y="-720.667" style="font-family:Arial;font-size:10px;">Mouse</text>
</g>
<!-- GO:0040010 -->
<g id="node24" class="node"><title>GO:0040010</title>
<polygon style="fill:goldenrod;stroke:goldenrod;" points="4217,-604 4217,-646 4301,-646 4301,-604 4217,-604"/>
<polygon style="fill:none;stroke:black;" points="4217,-604 4217,-646 4301,-646 4301,-604 4217,-604"/>
<text text-anchor="middle" x="4259" y="-635.667" style="font-family:Arial;font-size:10px;">positive regulation</text>
<text text-anchor="middle" x="4259" y="-623.667" style="font-family:Arial;font-size:10px;">of growth rate</text>
<text text-anchor="middle" x="4259" y="-611.667" style="font-family:Arial;font-size:10px;">Worm</text>
</g>
<!-- GO:0009651 -->
<g id="node25" class="node"><title>GO:0009651</title>
<polygon style="fill:yellowgreen;stroke:yellowgreen;" points="1574,-718 1574,-760 1632,-760 1632,-718 1574,-718"/>
<polygon style="fill:none;stroke:black;" points="1574,-718 1574,-760 1632,-760 1632,-718 1574,-718"/>
<text text-anchor="middle" x="1603" y="-749.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1603" y="-737.667" style="font-family:Arial;font-size:10px;">salt stress</text>
<text text-anchor="middle" x="1603" y="-725.667" style="font-family:Arial;font-size:10px;">Dicot</text>
</g>
<!-- GO:0035094 -->
<g id="node26" class="node"><title>GO:0035094</title>
<polygon style="fill:gold;stroke:gold;" points="1934,-604 1934,-646 1992,-646 1992,-604 1934,-604"/>
<polygon style="fill:none;stroke:black;" points="1934,-604 1934,-646 1992,-646 1992,-604 1934,-604"/>
<text text-anchor="middle" x="1963" y="-635.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1963" y="-623.667" style="font-family:Arial;font-size:10px;">nicotine</text>
<text text-anchor="middle" x="1963" y="-611.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0005634 -->
<g id="node28" class="node"><title>GO:0005634</title>
<polygon style="fill:white;stroke:white;" points="706,-453 706,-469 772,-469 772,-453 706,-453"/>
<polygon style="fill:none;stroke:black;" points="706,-453 706,-469 772,-469 772,-453 706,-453"/>
<text text-anchor="middle" x="739" y="-458.667" style="font-family:Arial;font-size:10px;">nucleus</text>
<polygon style="fill:tomato;stroke:tomato;" points="706,-437 706,-453 772,-453 772,-437 706,-437"/>
<polygon style="fill:none;stroke:black;" points="706,-437 706,-453 772,-453 772,-437 706,-437"/>
<text text-anchor="middle" x="739" y="-442.667" style="font-family:Arial;font-size:10px;">Human</text>
<polygon style="fill:gold;stroke:gold;" points="706,-421 706,-437 772,-437 772,-421 706,-421"/>
<polygon style="fill:none;stroke:black;" points="706,-421 706,-437 772,-437 772,-421 706,-421"/>
<text text-anchor="middle" x="739" y="-426.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
</g>
<!-- GO:0044428 -->
<g id="node137" class="node"><title>GO:0044428</title>
<polygon style="fill:white;stroke:white;" points="777,-356 777,-372 835,-372 835,-356 777,-356"/>
<polygon style="fill:none;stroke:black;" points="777,-356 777,-372 835,-372 835,-356 777,-356"/>
<text text-anchor="middle" x="806" y="-361.667" style="font-family:Arial;font-size:10px;">nuclear part</text>
</g>
<!-- GO:0005634&#45;&gt;GO:0044428 -->
<g id="edge381" class="edge"><title>GO:0005634&#45;&gt;GO:0044428</title>
<path style="fill:none;stroke:blue;" d="M755,-414C769,-401 787,-383 797,-372"/>
<polygon style="fill:blue;stroke:blue;" points="752.221,-411.781 747,-421 756.831,-417.049 752.221,-411.781"/>
</g>
<!-- GO:0005515 -->
<g id="node29" class="node"><title>GO:0005515</title>
<polygon style="fill:goldenrod;stroke:goldenrod;" points="11,-878 11,-908 81,-908 81,-878 11,-878"/>
<polygon style="fill:none;stroke:black;" points="11,-878 11,-908 81,-908 81,-878 11,-878"/>
<text text-anchor="middle" x="46" y="-897.667" style="font-family:Arial;font-size:10px;">protein binding</text>
<text text-anchor="middle" x="46" y="-885.667" style="font-family:Arial;font-size:10px;">Worm</text>
</g>
<!-- GO:0005515&#45;&gt;GO:0042802 -->
<g id="edge185" class="edge"><title>GO:0005515&#45;&gt;GO:0042802</title>
<path style="fill:none;stroke:gray;" d="M46,-868C45,-861 45,-853 45,-846"/>
<polygon style="fill:gray;stroke:gray;" points="42.5001,-868 46,-878 49.5001,-868 42.5001,-868"/>
</g>
<!-- GO:0043627 -->
<g id="node30" class="node"><title>GO:0043627</title>
<polygon style="fill:gold;stroke:gold;" points="2073,-604 2073,-646 2157,-646 2157,-604 2073,-604"/>
<polygon style="fill:none;stroke:black;" points="2073,-604 2073,-646 2157,-646 2157,-604 2073,-604"/>
<text text-anchor="middle" x="2115" y="-635.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="2115" y="-623.667" style="font-family:Arial;font-size:10px;">estrogen stimulus</text>
<text text-anchor="middle" x="2115" y="-611.667" style="font-family:Arial;font-size:10px;">Rat</text>
</g>
<!-- GO:0009408 -->
<g id="node31" class="node"><title>GO:0009408</title>
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<polygon style="fill:none;stroke:black;" points="1666,-718 1666,-760 1724,-760 1724,-718 1666,-718"/>
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<text text-anchor="middle" x="1695" y="-725.667" style="font-family:Arial;font-size:10px;">Rat</text>
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<g id="edge17" class="edge"><title>GO:0000003&#45;&gt;GO:0022414</title>
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<g id="node48" class="node"><title>GO:0032504</title>
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<text text-anchor="middle" x="1397" y="-885.667" style="font-family:Arial;font-size:10px;">organism reproduction</text>
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<!-- GO:0000003&#45;&gt;GO:0032504 -->
<g id="edge31" class="edge"><title>GO:0000003&#45;&gt;GO:0032504</title>
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<g id="node33" class="node"><title>GO:0005829</title>
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<g id="node34" class="node"><title>GO:0070062</title>
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<g id="node35" class="node"><title>GO:0005739</title>
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<g id="node36" class="node"><title>GO:0001666</title>
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<g id="node37" class="node"><title>GO:0005737</title>
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<g id="node136" class="node"><title>GO:0044444</title>
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<g id="edge361" class="edge"><title>GO:0005737&#45;&gt;GO:0044444</title>
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<g id="node38" class="node"><title>GO:0070061</title>
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<text text-anchor="middle" x="143" y="-606.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
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<!-- GO:0004332 -->
<g id="node39" class="node"><title>GO:0004332</title>
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<text text-anchor="middle" x="265" y="-639.667" style="font-family:Arial;font-size:10px;">Dicty: ISS_only</text>
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<text text-anchor="middle" x="265" y="-623.667" style="font-family:Arial;font-size:10px;">Rat: ISS_only</text>
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<text text-anchor="middle" x="265" y="-575.667" style="font-family:Arial;font-size:10px;">Fly</text>
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<!-- GO:0033057 -->
<g id="node41" class="node"><title>GO:0033057</title>
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<text text-anchor="middle" x="1390" y="-743.667" style="font-family:Arial;font-size:10px;">behavior in</text>
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<!-- GO:0033057&#45;&gt;GO:0018991 -->
<g id="edge3" class="edge"><title>GO:0033057&#45;&gt;GO:0018991</title>
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<polygon style="fill:gray;stroke:gray;" points="1386.5,-702 1390,-712 1393.5,-702 1386.5,-702"/>
</g>
<!-- GO:0019098 -->
<g id="node42" class="node"><title>GO:0019098</title>
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<text text-anchor="middle" x="1434" y="-829.667" style="font-family:Arial;font-size:10px;">reproductive</text>
<text text-anchor="middle" x="1434" y="-817.667" style="font-family:Arial;font-size:10px;">behavior</text>
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<!-- GO:0019098&#45;&gt;GO:0033057 -->
<g id="edge5" class="edge"><title>GO:0019098&#45;&gt;GO:0033057</title>
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<!-- GO:0007610 -->
<g id="node43" class="node"><title>GO:0007610</title>
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<polygon style="fill:none;stroke:black;" points="1574,-885 1574,-901 1616,-901 1616,-885 1574,-885"/>
<text text-anchor="middle" x="1595" y="-890.667" style="font-family:Arial;font-size:10px;">behavior</text>
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<!-- GO:0007610&#45;&gt;GO:0019098 -->
<g id="edge7" class="edge"><title>GO:0007610&#45;&gt;GO:0019098</title>
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</g>
<!-- GO:0050896&#45;&gt;GO:0007610 -->
<g id="edge9" class="edge"><title>GO:0050896&#45;&gt;GO:0007610</title>
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<g id="node114" class="node"><title>GO:0009607</title>
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<text text-anchor="middle" x="2231" y="-897.667" style="font-family:Arial;font-size:10px;">response to</text>
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<!-- GO:0050896&#45;&gt;GO:0009607 -->
<g id="edge273" class="edge"><title>GO:0050896&#45;&gt;GO:0009607</title>
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<g id="node115" class="node"><title>GO:0042221</title>
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<text text-anchor="middle" x="1988" y="-885.667" style="font-family:Arial;font-size:10px;">chemical stimulus</text>
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<!-- GO:0050896&#45;&gt;GO:0042221 -->
<g id="edge277" class="edge"><title>GO:0050896&#45;&gt;GO:0042221</title>
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<text text-anchor="middle" x="1787" y="-897.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1787" y="-885.667" style="font-family:Arial;font-size:10px;">stress</text>
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<!-- GO:0050896&#45;&gt;GO:0006950 -->
<g id="edge441" class="edge"><title>GO:0050896&#45;&gt;GO:0006950</title>
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<g id="node154" class="node"><title>GO:0009628</title>
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<text text-anchor="middle" x="1687" y="-897.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1687" y="-885.667" style="font-family:Arial;font-size:10px;">abiotic stimulus</text>
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<!-- GO:0050896&#45;&gt;GO:0009628 -->
<g id="edge445" class="edge"><title>GO:0050896&#45;&gt;GO:0009628</title>
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<!-- GO:0009719 -->
<g id="node160" class="node"><title>GO:0009719</title>
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<text text-anchor="middle" x="2113" y="-885.667" style="font-family:Arial;font-size:10px;">endogenous stimulus</text>
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<!-- GO:0050896&#45;&gt;GO:0009719 -->
<g id="edge465" class="edge"><title>GO:0050896&#45;&gt;GO:0009719</title>
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<g id="edge13" class="edge"><title>GO:0022414&#45;&gt;GO:0019098</title>
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<g id="node46" class="node"><title>GO:0048609</title>
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<!-- GO:0022414&#45;&gt;GO:0048609 -->
<g id="edge23" class="edge"><title>GO:0022414&#45;&gt;GO:0048609</title>
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<g id="edge21" class="edge"><title>GO:0048609&#45;&gt;GO:0033057</title>
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<g id="edge25" class="edge"><title>GO:0032501&#45;&gt;GO:0048609</title>
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<g id="edge33" class="edge"><title>GO:0032501&#45;&gt;GO:0032504</title>
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<text text-anchor="middle" x="3642" y="-897.667" style="font-family:Arial;font-size:10px;">multicellular</text>
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<!-- GO:0032501&#45;&gt;GO:0007275 -->
<g id="edge257" class="edge"><title>GO:0032501&#45;&gt;GO:0007275</title>
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<g id="edge267" class="edge"><title>GO:0032501&#45;&gt;GO:0003008</title>
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<g id="edge47" class="edge"><title>GO:0043226&#45;&gt;GO:0043229</title>
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<g id="edge353" class="edge"><title>GO:0043226&#45;&gt;GO:0043227</title>
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<g id="edge375" class="edge"><title>GO:0043226&#45;&gt;GO:0044422</title>
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<g id="edge481" class="edge"><title>GO:0043226&#45;&gt;GO:0031982</title>
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<g id="edge489" class="edge"><title>GO:0043226&#45;&gt;GO:0043230</title>
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<g id="edge45" class="edge"><title>GO:0043229&#45;&gt;GO:0043232</title>
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<g id="edge355" class="edge"><title>GO:0043229&#45;&gt;GO:0043231</title>
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<g id="edge379" class="edge"><title>GO:0043229&#45;&gt;GO:0044446</title>
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<g id="edge363" class="edge"><title>GO:0044424&#45;&gt;GO:0005737</title>
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<g id="edge49" class="edge"><title>GO:0044424&#45;&gt;GO:0043229</title>
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<!-- GO:0044424&#45;&gt;GO:0044446 -->
<g id="edge377" class="edge"><title>GO:0044424&#45;&gt;GO:0044446</title>
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<g id="edge407" class="edge"><title>GO:0044464&#45;&gt;GO:0016020</title>
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<g id="edge51" class="edge"><title>GO:0044464&#45;&gt;GO:0044424</title>
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<g id="edge61" class="edge"><title>GO:0044464&#45;&gt;GO:0005622</title>
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<!-- GO:0044464&#45;&gt;GO:0030312 -->
<g id="edge249" class="edge"><title>GO:0044464&#45;&gt;GO:0030312</title>
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<g id="edge413" class="edge"><title>GO:0044464&#45;&gt;GO:0042995</title>
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<g id="edge55" class="edge"><title>GO:0005623&#45;&gt;GO:0044464</title>
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<g id="edge59" class="edge"><title>GO:0005622&#45;&gt;GO:0044424</title>
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<!-- GO:0019318&#45;&gt;GO:0006000 -->
<g id="edge63" class="edge"><title>GO:0019318&#45;&gt;GO:0006000</title>
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<!-- GO:0019318&#45;&gt;GO:0006006 -->
<g id="edge293" class="edge"><title>GO:0019318&#45;&gt;GO:0006006</title>
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<g id="edge297" class="edge"><title>GO:0019318&#45;&gt;GO:0019320</title>
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<g id="edge65" class="edge"><title>GO:0005996&#45;&gt;GO:0019318</title>
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<g id="edge301" class="edge"><title>GO:0005996&#45;&gt;GO:0046365</title>
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<g id="edge67" class="edge"><title>GO:0006066&#45;&gt;GO:0005996</title>
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<text text-anchor="middle" x="2871" y="-629.667" style="font-family:Arial;font-size:10px;">alcohol catabolic</text>
<text text-anchor="middle" x="2871" y="-617.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0006066&#45;&gt;GO:0046164 -->
<g id="edge339" class="edge"><title>GO:0006066&#45;&gt;GO:0046164</title>
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<text text-anchor="middle" x="2725" y="-829.667" style="font-family:Arial;font-size:10px;">cellular metabolic</text>
<text text-anchor="middle" x="2725" y="-817.667" style="font-family:Arial;font-size:10px;">process</text>
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<g id="edge69" class="edge"><title>GO:0044237&#45;&gt;GO:0006066</title>
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<text text-anchor="middle" x="2596" y="-629.667" style="font-family:Arial;font-size:10px;">cellular carbohydrate</text>
<text text-anchor="middle" x="2596" y="-617.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0044237&#45;&gt;GO:0044262 -->
<g id="edge87" class="edge"><title>GO:0044237&#45;&gt;GO:0044262</title>
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<text text-anchor="middle" x="2400" y="-761.667" style="font-family:Arial;font-size:10px;">nucleobase,</text>
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<!-- GO:0044237&#45;&gt;GO:0006139 -->
<g id="edge121" class="edge"><title>GO:0044237&#45;&gt;GO:0006139</title>
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<!-- GO:0044248 -->
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<text text-anchor="middle" x="2870" y="-743.667" style="font-family:Arial;font-size:10px;">cellular catabolic</text>
<text text-anchor="middle" x="2870" y="-731.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0044237&#45;&gt;GO:0044248 -->
<g id="edge329" class="edge"><title>GO:0044237&#45;&gt;GO:0044248</title>
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<text text-anchor="middle" x="2996" y="-743.667" style="font-family:Arial;font-size:10px;">cellular macromolecule</text>
<text text-anchor="middle" x="2996" y="-731.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0044237&#45;&gt;GO:0044260 -->
<g id="edge335" class="edge"><title>GO:0044237&#45;&gt;GO:0044260</title>
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<!-- GO:0006091 -->
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<polygon style="fill:none;stroke:black;" points="2429,-262 2429,-304 2529,-304 2529,-262 2429,-262"/>
<text text-anchor="middle" x="2479" y="-293.667" style="font-family:Arial;font-size:10px;">generation of</text>
<text text-anchor="middle" x="2479" y="-281.667" style="font-family:Arial;font-size:10px;">precursor metabolites</text>
<text text-anchor="middle" x="2479" y="-269.667" style="font-family:Arial;font-size:10px;">and energy</text>
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<!-- GO:0044237&#45;&gt;GO:0006091 -->
<g id="edge345" class="edge"><title>GO:0044237&#45;&gt;GO:0006091</title>
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<!-- GO:0008152&#45;&gt;GO:0044237 -->
<g id="edge71" class="edge"><title>GO:0008152&#45;&gt;GO:0044237</title>
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<!-- GO:0044238 -->
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<text text-anchor="middle" x="2596" y="-829.667" style="font-family:Arial;font-size:10px;">primary metabolic</text>
<text text-anchor="middle" x="2596" y="-817.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0008152&#45;&gt;GO:0044238 -->
<g id="edge85" class="edge"><title>GO:0008152&#45;&gt;GO:0044238</title>
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<!-- GO:0009056 -->
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<text text-anchor="middle" x="2851" y="-822.667" style="font-family:Arial;font-size:10px;">catabolic process</text>
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<!-- GO:0008152&#45;&gt;GO:0009056 -->
<g id="edge311" class="edge"><title>GO:0008152&#45;&gt;GO:0009056</title>
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<!-- GO:0043170 -->
<g id="node128" class="node"><title>GO:0043170</title>
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<text text-anchor="middle" x="2996" y="-829.667" style="font-family:Arial;font-size:10px;">macromolecule</text>
<text text-anchor="middle" x="2996" y="-817.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0008152&#45;&gt;GO:0043170 -->
<g id="edge323" class="edge"><title>GO:0008152&#45;&gt;GO:0043170</title>
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<!-- GO:0009987&#45;&gt;GO:0044237 -->
<g id="edge75" class="edge"><title>GO:0009987&#45;&gt;GO:0044237</title>
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<!-- GO:0019725 -->
<g id="node67" class="node"><title>GO:0019725</title>
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<text text-anchor="middle" x="3375" y="-736.667" style="font-family:Arial;font-size:10px;">cellular homeostasis</text>
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<!-- GO:0009987&#45;&gt;GO:0019725 -->
<g id="edge91" class="edge"><title>GO:0009987&#45;&gt;GO:0019725</title>
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<!-- GO:0050794 -->
<g id="node102" class="node"><title>GO:0050794</title>
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<text text-anchor="middle" x="3412" y="-829.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="3412" y="-817.667" style="font-family:Arial;font-size:10px;">cellular process</text>
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<!-- GO:0009987&#45;&gt;GO:0050794 -->
<g id="edge225" class="edge"><title>GO:0009987&#45;&gt;GO:0050794</title>
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<!-- GO:0016043 -->
<g id="node103" class="node"><title>GO:0016043</title>
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<text text-anchor="middle" x="3527" y="-829.667" style="font-family:Arial;font-size:10px;">cellular component</text>
<text text-anchor="middle" x="3527" y="-817.667" style="font-family:Arial;font-size:10px;">organization</text>
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<!-- GO:0009987&#45;&gt;GO:0016043 -->
<g id="edge229" class="edge"><title>GO:0009987&#45;&gt;GO:0016043</title>
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<!-- GO:0048869 -->
<g id="node106" class="node"><title>GO:0048869</title>
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<text text-anchor="middle" x="3656" y="-829.667" style="font-family:Arial;font-size:10px;">cellular developmental</text>
<text text-anchor="middle" x="3656" y="-817.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0009987&#45;&gt;GO:0048869 -->
<g id="edge241" class="edge"><title>GO:0009987&#45;&gt;GO:0048869</title>
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<!-- GO:0044262&#45;&gt;GO:0005996 -->
<g id="edge79" class="edge"><title>GO:0044262&#45;&gt;GO:0005996</title>
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<!-- GO:0044275 -->
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<text text-anchor="middle" x="2789" y="-527.667" style="font-family:Arial;font-size:10px;">cellular carbohydrate</text>
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<!-- GO:0044262&#45;&gt;GO:0044275 -->
<g id="edge313" class="edge"><title>GO:0044262&#45;&gt;GO:0044275</title>
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<!-- GO:0005975 -->
<g id="node65" class="node"><title>GO:0005975</title>
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<text text-anchor="middle" x="2596" y="-743.667" style="font-family:Arial;font-size:10px;">carbohydrate</text>
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<!-- GO:0005975&#45;&gt;GO:0044262 -->
<g id="edge81" class="edge"><title>GO:0005975&#45;&gt;GO:0044262</title>
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<!-- GO:0016052 -->
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<!-- GO:0005975&#45;&gt;GO:0016052 -->
<g id="edge307" class="edge"><title>GO:0005975&#45;&gt;GO:0016052</title>
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<!-- GO:0044238&#45;&gt;GO:0005975 -->
<g id="edge83" class="edge"><title>GO:0044238&#45;&gt;GO:0005975</title>
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<!-- GO:0044238&#45;&gt;GO:0006139 -->
<g id="edge123" class="edge"><title>GO:0044238&#45;&gt;GO:0006139</title>
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<g id="edge89" class="edge"><title>GO:0019725&#45;&gt;GO:0046716</title>
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<text text-anchor="middle" x="3235" y="-829.667" style="font-family:Arial;font-size:10px;">homeostatic</text>
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<!-- GO:0042592&#45;&gt;GO:0019725 -->
<g id="edge93" class="edge"><title>GO:0042592&#45;&gt;GO:0019725</title>
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<text text-anchor="middle" x="3246" y="-743.667" style="font-family:Arial;font-size:10px;">anatomical structure</text>
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<!-- GO:0042592&#45;&gt;GO:0060249 -->
<g id="edge103" class="edge"><title>GO:0042592&#45;&gt;GO:0060249</title>
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<text text-anchor="middle" x="3252" y="-897.667" style="font-family:Arial;font-size:10px;">regulation of</text>
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<!-- GO:0065008&#45;&gt;GO:0008360 -->
<g id="edge245" class="edge"><title>GO:0065008&#45;&gt;GO:0008360</title>
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<g id="edge95" class="edge"><title>GO:0065008&#45;&gt;GO:0042592</title>
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<!-- GO:0065007&#45;&gt;GO:0065008 -->
<g id="edge97" class="edge"><title>GO:0065007&#45;&gt;GO:0065008</title>
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<!-- GO:0065007&#45;&gt;GO:0050789 -->
<g id="edge203" class="edge"><title>GO:0065007&#45;&gt;GO:0050789</title>
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<g id="edge101" class="edge"><title>GO:0060249&#45;&gt;GO:0046716</title>
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<text text-anchor="middle" x="2077" y="-123.667" style="font-family:Arial;font-size:10px;">triphosphate</text>
<text text-anchor="middle" x="2077" y="-111.667" style="font-family:Arial;font-size:10px;">biosynthetic</text>
<text text-anchor="middle" x="2077" y="-99.6667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0009206&#45;&gt;GO:0006754 -->
<g id="edge105" class="edge"><title>GO:0009206&#45;&gt;GO:0006754</title>
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<!-- GO:0009145&#45;&gt;GO:0009206 -->
<g id="edge107" class="edge"><title>GO:0009145&#45;&gt;GO:0009206</title>
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<!-- GO:0006164 -->
<g id="node74" class="node"><title>GO:0006164</title>
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<text text-anchor="middle" x="1843" y="-293.667" style="font-family:Arial;font-size:10px;">purine nucleotide</text>
<text text-anchor="middle" x="1843" y="-281.667" style="font-family:Arial;font-size:10px;">biosynthetic</text>
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<!-- GO:0006164&#45;&gt;GO:0009145 -->
<g id="edge109" class="edge"><title>GO:0006164&#45;&gt;GO:0009145</title>
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<g id="node84" class="node"><title>GO:0009152</title>
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<text text-anchor="middle" x="1846" y="-185.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0006164&#45;&gt;GO:0009152 -->
<g id="edge145" class="edge"><title>GO:0006164&#45;&gt;GO:0009152</title>
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<text text-anchor="middle" x="2107" y="-368.667" style="font-family:Arial;font-size:10px;">purine nucleotide</text>
<text text-anchor="middle" x="2107" y="-356.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
</g>
<!-- GO:0006163&#45;&gt;GO:0006164 -->
<g id="edge111" class="edge"><title>GO:0006163&#45;&gt;GO:0006164</title>
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<!-- GO:0009144 -->
<g id="node83" class="node"><title>GO:0009144</title>
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<polygon style="fill:none;stroke:black;" points="2309,-262 2309,-304 2395,-304 2395,-262 2309,-262"/>
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<text text-anchor="middle" x="2352" y="-281.667" style="font-family:Arial;font-size:10px;">triphosphate</text>
<text text-anchor="middle" x="2352" y="-269.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0006163&#45;&gt;GO:0009144 -->
<g id="edge139" class="edge"><title>GO:0006163&#45;&gt;GO:0009144</title>
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<!-- GO:0009150 -->
<g id="node85" class="node"><title>GO:0009150</title>
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<polygon style="fill:none;stroke:black;" points="2059,-268 2059,-298 2155,-298 2155,-268 2059,-268"/>
<text text-anchor="middle" x="2107" y="-287.667" style="font-family:Arial;font-size:10px;">purine ribonucleotide</text>
<text text-anchor="middle" x="2107" y="-275.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
</g>
<!-- GO:0006163&#45;&gt;GO:0009150 -->
<g id="edge149" class="edge"><title>GO:0006163&#45;&gt;GO:0009150</title>
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<!-- GO:0009117 -->
<g id="node76" class="node"><title>GO:0009117</title>
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<polygon style="fill:none;stroke:black;" points="2059,-430 2059,-460 2155,-460 2155,-430 2059,-430"/>
<text text-anchor="middle" x="2107" y="-449.667" style="font-family:Arial;font-size:10px;">nucleotide metabolic</text>
<text text-anchor="middle" x="2107" y="-437.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0009117&#45;&gt;GO:0006163 -->
<g id="edge113" class="edge"><title>GO:0009117&#45;&gt;GO:0006163</title>
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<!-- GO:0009165 -->
<g id="node80" class="node"><title>GO:0009165</title>
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<polygon style="fill:none;stroke:black;" points="1797,-349 1797,-379 1903,-379 1903,-349 1797,-349"/>
<text text-anchor="middle" x="1850" y="-368.667" style="font-family:Arial;font-size:10px;">nucleotide biosynthetic</text>
<text text-anchor="middle" x="1850" y="-356.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0009117&#45;&gt;GO:0009165 -->
<g id="edge127" class="edge"><title>GO:0009117&#45;&gt;GO:0009165</title>
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<!-- GO:0009141 -->
<g id="node82" class="node"><title>GO:0009141</title>
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<polygon style="fill:none;stroke:black;" points="2184,-349 2184,-379 2292,-379 2292,-349 2184,-349"/>
<text text-anchor="middle" x="2238" y="-368.667" style="font-family:Arial;font-size:10px;">nucleoside triphosphate</text>
<text text-anchor="middle" x="2238" y="-356.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
</g>
<!-- GO:0009117&#45;&gt;GO:0009141 -->
<g id="edge133" class="edge"><title>GO:0009117&#45;&gt;GO:0009141</title>
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<!-- GO:0009259 -->
<g id="node86" class="node"><title>GO:0009259</title>
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<polygon style="fill:none;stroke:black;" points="1944,-349 1944,-379 2030,-379 2030,-349 1944,-349"/>
<text text-anchor="middle" x="1987" y="-368.667" style="font-family:Arial;font-size:10px;">ribonucleotide</text>
<text text-anchor="middle" x="1987" y="-356.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
</g>
<!-- GO:0009117&#45;&gt;GO:0009259 -->
<g id="edge153" class="edge"><title>GO:0009117&#45;&gt;GO:0009259</title>
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<polygon style="fill:gray;stroke:gray;" points="2074.74,-427.365 2085,-430 2078.62,-421.541 2074.74,-427.365"/>
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<!-- GO:0006753 -->
<g id="node77" class="node"><title>GO:0006753</title>
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<polygon style="fill:none;stroke:black;" points="2325,-508 2325,-538 2425,-538 2425,-508 2325,-508"/>
<text text-anchor="middle" x="2375" y="-527.667" style="font-family:Arial;font-size:10px;">nucleoside phosphate</text>
<text text-anchor="middle" x="2375" y="-515.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
</g>
<!-- GO:0006753&#45;&gt;GO:0009117 -->
<g id="edge115" class="edge"><title>GO:0006753&#45;&gt;GO:0009117</title>
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<!-- GO:0055086 -->
<g id="node78" class="node"><title>GO:0055086</title>
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<polygon style="fill:none;stroke:black;" points="2346,-598 2346,-652 2442,-652 2442,-598 2346,-598"/>
<text text-anchor="middle" x="2394" y="-641.667" style="font-family:Arial;font-size:10px;">nucleobase,</text>
<text text-anchor="middle" x="2394" y="-629.667" style="font-family:Arial;font-size:10px;">nucleoside and</text>
<text text-anchor="middle" x="2394" y="-617.667" style="font-family:Arial;font-size:10px;">nucleotide metabolic</text>
<text text-anchor="middle" x="2394" y="-605.667" style="font-family:Arial;font-size:10px;">process</text>
</g>
<!-- GO:0055086&#45;&gt;GO:0006753 -->
<g id="edge117" class="edge"><title>GO:0055086&#45;&gt;GO:0006753</title>
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<!-- GO:0006139&#45;&gt;GO:0055086 -->
<g id="edge119" class="edge"><title>GO:0006139&#45;&gt;GO:0055086</title>
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<!-- GO:0009165&#45;&gt;GO:0006164 -->
<g id="edge125" class="edge"><title>GO:0009165&#45;&gt;GO:0006164</title>
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<!-- GO:0009142 -->
<g id="node81" class="node"><title>GO:0009142</title>
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<polygon style="fill:none;stroke:black;" points="1917,-262 1917,-304 2025,-304 2025,-262 1917,-262"/>
<text text-anchor="middle" x="1971" y="-293.667" style="font-family:Arial;font-size:10px;">nucleoside triphosphate</text>
<text text-anchor="middle" x="1971" y="-281.667" style="font-family:Arial;font-size:10px;">biosynthetic</text>
<text text-anchor="middle" x="1971" y="-269.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0009165&#45;&gt;GO:0009142 -->
<g id="edge135" class="edge"><title>GO:0009165&#45;&gt;GO:0009142</title>
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<!-- GO:0009260 -->
<g id="node87" class="node"><title>GO:0009260</title>
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<text text-anchor="middle" x="1736" y="-293.667" style="font-family:Arial;font-size:10px;">ribonucleotide</text>
<text text-anchor="middle" x="1736" y="-281.667" style="font-family:Arial;font-size:10px;">biosynthetic</text>
<text text-anchor="middle" x="1736" y="-269.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0009165&#45;&gt;GO:0009260 -->
<g id="edge157" class="edge"><title>GO:0009165&#45;&gt;GO:0009260</title>
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<!-- GO:0009142&#45;&gt;GO:0009145 -->
<g id="edge129" class="edge"><title>GO:0009142&#45;&gt;GO:0009145</title>
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<!-- GO:0009201 -->
<g id="node88" class="node"><title>GO:0009201</title>
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<polygon style="fill:none;stroke:black;" points="1934,-172 1934,-226 2002,-226 2002,-172 1934,-172"/>
<text text-anchor="middle" x="1968" y="-215.667" style="font-family:Arial;font-size:10px;">ribonucleoside</text>
<text text-anchor="middle" x="1968" y="-203.667" style="font-family:Arial;font-size:10px;">triphosphate</text>
<text text-anchor="middle" x="1968" y="-191.667" style="font-family:Arial;font-size:10px;">biosynthetic</text>
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<!-- GO:0009142&#45;&gt;GO:0009201 -->
<g id="edge163" class="edge"><title>GO:0009142&#45;&gt;GO:0009201</title>
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<!-- GO:0009141&#45;&gt;GO:0009142 -->
<g id="edge131" class="edge"><title>GO:0009141&#45;&gt;GO:0009142</title>
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<!-- GO:0009141&#45;&gt;GO:0009144 -->
<g id="edge141" class="edge"><title>GO:0009141&#45;&gt;GO:0009144</title>
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<!-- GO:0009199 -->
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<text text-anchor="middle" x="2232" y="-293.667" style="font-family:Arial;font-size:10px;">ribonucleoside</text>
<text text-anchor="middle" x="2232" y="-281.667" style="font-family:Arial;font-size:10px;">triphosphate</text>
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<!-- GO:0009141&#45;&gt;GO:0009199 -->
<g id="edge167" class="edge"><title>GO:0009141&#45;&gt;GO:0009199</title>
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<!-- GO:0009144&#45;&gt;GO:0009145 -->
<g id="edge137" class="edge"><title>GO:0009144&#45;&gt;GO:0009145</title>
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<text text-anchor="middle" x="2201" y="-209.667" style="font-family:Arial;font-size:10px;">purine ribonucleoside</text>
<text text-anchor="middle" x="2201" y="-197.667" style="font-family:Arial;font-size:10px;">triphosphate</text>
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<!-- GO:0009144&#45;&gt;GO:0009205 -->
<g id="edge175" class="edge"><title>GO:0009144&#45;&gt;GO:0009205</title>
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<!-- GO:0009152&#45;&gt;GO:0009206 -->
<g id="edge143" class="edge"><title>GO:0009152&#45;&gt;GO:0009206</title>
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<g id="edge147" class="edge"><title>GO:0009150&#45;&gt;GO:0009152</title>
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<!-- GO:0009150&#45;&gt;GO:0009205 -->
<g id="edge177" class="edge"><title>GO:0009150&#45;&gt;GO:0009205</title>
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<g id="edge261" class="edge"><title>GO:0006936&#45;&gt;GO:0006941</title>
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<text text-anchor="middle" x="1236" y="-817.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0003012&#45;&gt;GO:0006936 -->
<g id="edge263" class="edge"><title>GO:0003012&#45;&gt;GO:0006936</title>
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<!-- GO:0003008&#45;&gt;GO:0003012 -->
<g id="edge265" class="edge"><title>GO:0003008&#45;&gt;GO:0003012</title>
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<text text-anchor="middle" x="2229" y="-611.667" style="font-family:Arial;font-size:10px;">bacterial origin</text>
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<!-- GO:0002237&#45;&gt;GO:0032496 -->
<g id="edge269" class="edge"><title>GO:0002237&#45;&gt;GO:0032496</title>
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<!-- GO:0009607&#45;&gt;GO:0051707 -->
<g id="edge283" class="edge"><title>GO:0009607&#45;&gt;GO:0051707</title>
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<!-- GO:0042221&#45;&gt;GO:0002237 -->
<g id="edge275" class="edge"><title>GO:0042221&#45;&gt;GO:0002237</title>
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<!-- GO:0042221&#45;&gt;GO:0010035 -->
<g id="edge405" class="edge"><title>GO:0042221&#45;&gt;GO:0010035</title>
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<!-- GO:0042221&#45;&gt;GO:0010033 -->
<g id="edge451" class="edge"><title>GO:0042221&#45;&gt;GO:0010033</title>
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<!-- GO:0042221&#45;&gt;GO:0009725 -->
<g id="edge467" class="edge"><title>GO:0042221&#45;&gt;GO:0009725</title>
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<!-- GO:0009617&#45;&gt;GO:0002237 -->
<g id="edge279" class="edge"><title>GO:0009617&#45;&gt;GO:0002237</title>
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<g id="edge281" class="edge"><title>GO:0051707&#45;&gt;GO:0009617</title>
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<!-- GO:0051704&#45;&gt;GO:0051707 -->
<g id="edge285" class="edge"><title>GO:0051704&#45;&gt;GO:0051707</title>
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<!-- GO:0006007&#45;&gt;GO:0006096 -->
<g id="edge289" class="edge"><title>GO:0006007&#45;&gt;GO:0006096</title>
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<!-- GO:0006006&#45;&gt;GO:0006007 -->
<g id="edge291" class="edge"><title>GO:0006006&#45;&gt;GO:0006007</title>
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<!-- GO:0019320&#45;&gt;GO:0006007 -->
<g id="edge295" class="edge"><title>GO:0019320&#45;&gt;GO:0006007</title>
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<g id="edge299" class="edge"><title>GO:0046365&#45;&gt;GO:0019320</title>
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<g id="edge303" class="edge"><title>GO:0044275&#45;&gt;GO:0046365</title>
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<g id="edge305" class="edge"><title>GO:0016052&#45;&gt;GO:0044275</title>
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<g id="edge309" class="edge"><title>GO:0009056&#45;&gt;GO:0016052</title>
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<!-- GO:0009056&#45;&gt;GO:0009057 -->
<g id="edge319" class="edge"><title>GO:0009056&#45;&gt;GO:0009057</title>
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<g id="edge327" class="edge"><title>GO:0009056&#45;&gt;GO:0044248</title>
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<g id="edge315" class="edge"><title>GO:0044265&#45;&gt;GO:0044275</title>
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<g id="edge333" class="edge"><title>GO:0043170&#45;&gt;GO:0044260</title>
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<!-- GO:0009536&#45;&gt;GO:0009507 -->
<g id="edge347" class="edge"><title>GO:0009536&#45;&gt;GO:0009507</title>
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<g id="edge351" class="edge"><title>GO:0043227&#45;&gt;GO:0043231</title>
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<g id="edge357" class="edge"><title>GO:0044444&#45;&gt;GO:0009536</title>
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</g>
<!-- GO:0044428&#45;&gt;GO:0005730 -->
<g id="edge367" class="edge"><title>GO:0044428&#45;&gt;GO:0005730</title>
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<polygon style="fill:gray;stroke:gray;" points="795.74,-348.283 803,-356 802.137,-345.44 795.74,-348.283"/>
</g>
<!-- GO:0031981 -->
<g id="node140" class="node"><title>GO:0031981</title>
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<polygon style="fill:none;stroke:black;" points="807,-275 807,-291 873,-291 873,-275 807,-275"/>
<text text-anchor="middle" x="840" y="-280.667" style="font-family:Arial;font-size:10px;">nuclear lumen</text>
</g>
<!-- GO:0044428&#45;&gt;GO:0031981 -->
<g id="edge387" class="edge"><title>GO:0044428&#45;&gt;GO:0031981</title>
<path style="fill:none;stroke:gray;" d="M813,-346C821,-329 831,-304 836,-291"/>
<polygon style="fill:gray;stroke:gray;" points="809.464,-345.415 809,-356 815.964,-348.015 809.464,-345.415"/>
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<!-- GO:0044446&#45;&gt;GO:0044428 -->
<g id="edge369" class="edge"><title>GO:0044446&#45;&gt;GO:0044428</title>
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</g>
<!-- GO:0070013 -->
<g id="node141" class="node"><title>GO:0070013</title>
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<polygon style="fill:none;stroke:black;" points="1088,-430 1088,-460 1162,-460 1162,-430 1088,-430"/>
<text text-anchor="middle" x="1125" y="-449.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="1125" y="-437.667" style="font-family:Arial;font-size:10px;">organelle lumen</text>
</g>
<!-- GO:0044446&#45;&gt;GO:0070013 -->
<g id="edge399" class="edge"><title>GO:0044446&#45;&gt;GO:0070013</title>
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<!-- GO:0044422&#45;&gt;GO:0044446 -->
<g id="edge371" class="edge"><title>GO:0044422&#45;&gt;GO:0044446</title>
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<polygon style="fill:gray;stroke:gray;" points="1071.74,-609.283 1079,-617 1078.14,-606.44 1071.74,-609.283"/>
</g>
<!-- GO:0043233 -->
<g id="node142" class="node"><title>GO:0043233</title>
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<polygon style="fill:none;stroke:black;" points="1106,-515 1106,-531 1180,-531 1180,-515 1106,-515"/>
<text text-anchor="middle" x="1143" y="-520.667" style="font-family:Arial;font-size:10px;">organelle lumen</text>
</g>
<!-- GO:0044422&#45;&gt;GO:0043233 -->
<g id="edge397" class="edge"><title>GO:0044422&#45;&gt;GO:0043233</title>
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<polygon style="fill:gray;stroke:gray;" points="1088.8,-606.559 1087,-617 1094.92,-609.958 1088.8,-606.559"/>
</g>
<!-- GO:0031981&#45;&gt;GO:0005730 -->
<g id="edge385" class="edge"><title>GO:0031981&#45;&gt;GO:0005730</title>
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<polygon style="fill:blue;stroke:blue;" points="824.2,-269.1 833,-275 829.8,-264.9 824.2,-269.1"/>
</g>
<!-- GO:0070013&#45;&gt;GO:0031981 -->
<g id="edge389" class="edge"><title>GO:0070013&#45;&gt;GO:0031981</title>
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<polygon style="fill:gray;stroke:gray;" points="1095.9,-426.8 1106,-430 1100.1,-421.2 1095.9,-426.8"/>
</g>
<!-- GO:0043233&#45;&gt;GO:0070013 -->
<g id="edge391" class="edge"><title>GO:0043233&#45;&gt;GO:0070013</title>
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<polygon style="fill:gray;stroke:gray;" points="1135.61,-505.881 1141,-515 1142.47,-504.508 1135.61,-505.881"/>
</g>
<!-- GO:0031974&#45;&gt;GO:0043233 -->
<g id="edge393" class="edge"><title>GO:0031974&#45;&gt;GO:0043233</title>
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<polygon style="fill:gray;stroke:gray;" points="1158.52,-924.398 1163,-934 1165.49,-923.701 1158.52,-924.398"/>
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<!-- GO:0010038 -->
<g id="node144" class="node"><title>GO:0010038</title>
<polygon style="fill:white;stroke:white;" points="1793,-724 1793,-754 1851,-754 1851,-724 1793,-724"/>
<polygon style="fill:none;stroke:black;" points="1793,-724 1793,-754 1851,-754 1851,-724 1793,-724"/>
<text text-anchor="middle" x="1822" y="-743.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1822" y="-731.667" style="font-family:Arial;font-size:10px;">metal ion</text>
</g>
<!-- GO:0010038&#45;&gt;GO:0046686 -->
<g id="edge401" class="edge"><title>GO:0010038&#45;&gt;GO:0046686</title>
<path style="fill:none;stroke:gray;" d="M1822,-714C1822,-694 1822,-665 1822,-646"/>
<polygon style="fill:gray;stroke:gray;" points="1818.5,-714 1822,-724 1825.5,-714 1818.5,-714"/>
</g>
<!-- GO:0010035&#45;&gt;GO:0010038 -->
<g id="edge403" class="edge"><title>GO:0010035&#45;&gt;GO:0010038</title>
<path style="fill:none;stroke:gray;" d="M1856,-801C1848,-786 1837,-767 1830,-754"/>
<polygon style="fill:gray;stroke:gray;" points="1853.08,-802.958 1861,-810 1859.2,-799.559 1853.08,-802.958"/>
</g>
<!-- GO:0042995&#45;&gt;GO:0019861 -->
<g id="edge411" class="edge"><title>GO:0042995&#45;&gt;GO:0019861</title>
<path style="fill:none;stroke:gray;" d="M664,-807C666,-793 668,-774 670,-763"/>
<polygon style="fill:gray;stroke:gray;" points="660.529,-806.508 662,-817 667.393,-807.881 660.529,-806.508"/>
</g>
<!-- GO:0040009 -->
<g id="node147" class="node"><title>GO:0040009</title>
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<polygon style="fill:none;stroke:black;" points="4283,-724 4283,-754 4341,-754 4341,-724 4283,-724"/>
<text text-anchor="middle" x="4312" y="-743.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="4312" y="-731.667" style="font-family:Arial;font-size:10px;">growth rate</text>
</g>
<!-- GO:0040009&#45;&gt;GO:0040010 -->
<g id="edge415" class="edge"><title>GO:0040009&#45;&gt;GO:0040010</title>
<path style="fill:none;stroke:gray;" d="M4300,-715C4291,-694 4278,-666 4269,-646"/>
<polygon style="fill:gray;stroke:gray;" points="4297.08,-716.958 4305,-724 4303.2,-713.559 4297.08,-716.958"/>
</g>
<!-- GO:0040008&#45;&gt;GO:0040009 -->
<g id="edge417" class="edge"><title>GO:0040008&#45;&gt;GO:0040009</title>
<path style="fill:none;stroke:gray;" d="M4274,-801C4284,-786 4295,-767 4303,-754"/>
<polygon style="fill:gray;stroke:gray;" points="4270.8,-799.559 4269,-810 4276.92,-802.958 4270.8,-799.559"/>
</g>
<!-- GO:0045927 -->
<g id="node150" class="node"><title>GO:0045927</title>
<polygon style="fill:white;stroke:white;" points="4165,-724 4165,-754 4249,-754 4249,-724 4165,-724"/>
<polygon style="fill:none;stroke:black;" points="4165,-724 4165,-754 4249,-754 4249,-724 4165,-724"/>
<text text-anchor="middle" x="4207" y="-743.667" style="font-family:Arial;font-size:10px;">positive regulation</text>
<text text-anchor="middle" x="4207" y="-731.667" style="font-family:Arial;font-size:10px;">of growth</text>
</g>
<!-- GO:0040008&#45;&gt;GO:0045927 -->
<g id="edge427" class="edge"><title>GO:0040008&#45;&gt;GO:0045927</title>
<path style="fill:none;stroke:gray;" d="M4245,-801C4236,-786 4224,-767 4216,-754"/>
<polygon style="fill:gray;stroke:gray;" points="4242.54,-803.621 4251,-810 4248.37,-799.738 4242.54,-803.621"/>
</g>
<!-- GO:0040007&#45;&gt;GO:0040008 -->
<g id="edge421" class="edge"><title>GO:0040007&#45;&gt;GO:0040008</title>
<path style="fill:none;stroke:black;" d="M4260,-875C4260,-864 4260,-850 4260,-840"/>
<polygon style="fill:black;stroke:black;" points="4256.5,-875 4260,-885 4263.5,-875 4256.5,-875"/>
</g>
<!-- GO:0040007&#45;&gt;GO:0045927 -->
<g id="edge435" class="edge"><title>GO:0040007&#45;&gt;GO:0045927</title>
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</g>
<!-- GO:0045927&#45;&gt;GO:0040010 -->
<g id="edge425" class="edge"><title>GO:0045927&#45;&gt;GO:0040010</title>
<path style="fill:none;stroke:gray;" d="M4218,-715C4227,-694 4240,-666 4249,-646"/>
<polygon style="fill:gray;stroke:gray;" points="4214.86,-713.44 4214,-724 4221.26,-716.283 4214.86,-713.44"/>
</g>
<!-- GO:0048518&#45;&gt;GO:0045927 -->
<g id="edge429" class="edge"><title>GO:0048518&#45;&gt;GO:0045927</title>
<path style="fill:none;stroke:gray;" d="M4173,-795C4181,-781 4191,-765 4198,-754"/>
<polygon style="fill:gray;stroke:gray;" points="4169.8,-793.559 4168,-804 4175.92,-796.958 4169.8,-793.559"/>
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<!-- GO:0006970 -->
<g id="node152" class="node"><title>GO:0006970</title>
<polygon style="fill:white;stroke:white;" points="1589,-810 1589,-840 1659,-840 1659,-810 1589,-810"/>
<polygon style="fill:none;stroke:black;" points="1589,-810 1589,-840 1659,-840 1659,-810 1589,-810"/>
<text text-anchor="middle" x="1624" y="-829.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1624" y="-817.667" style="font-family:Arial;font-size:10px;">osmotic stress</text>
</g>
<!-- GO:0006970&#45;&gt;GO:0009651 -->
<g id="edge437" class="edge"><title>GO:0006970&#45;&gt;GO:0009651</title>
<path style="fill:none;stroke:gray;" d="M1618,-800C1615,-787 1611,-773 1608,-760"/>
<polygon style="fill:gray;stroke:gray;" points="1614.61,-800.881 1620,-810 1621.47,-799.508 1614.61,-800.881"/>
</g>
<!-- GO:0006950&#45;&gt;GO:0009408 -->
<g id="edge469" class="edge"><title>GO:0006950&#45;&gt;GO:0009408</title>
<path style="fill:none;stroke:gray;" d="M1749,-877C1733,-870 1718,-862 1714,-856 1693,-827 1691,-785 1693,-760"/>
<polygon style="fill:gray;stroke:gray;" points="1747.44,-880.137 1758,-881 1750.28,-873.74 1747.44,-880.137"/>
</g>
<!-- GO:0006950&#45;&gt;GO:0001666 -->
<g id="edge501" class="edge"><title>GO:0006950&#45;&gt;GO:0001666</title>
<path style="fill:none;stroke:gray;" d="M1777,-869C1774,-861 1771,-853 1768,-846"/>
<polygon style="fill:gray;stroke:gray;" points="1773.74,-870.283 1781,-878 1780.14,-867.44 1773.74,-870.283"/>
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<!-- GO:0006950&#45;&gt;GO:0006970 -->
<g id="edge439" class="edge"><title>GO:0006950&#45;&gt;GO:0006970</title>
<path style="fill:none;stroke:gray;" d="M1748,-877C1746,-876 1743,-875 1741,-874 1714,-864 1706,-866 1681,-856 1670,-851 1659,-845 1650,-840"/>
<polygon style="fill:gray;stroke:gray;" points="1747.42,-880.479 1758,-880 1749.43,-873.774 1747.42,-880.479"/>
</g>
<!-- GO:0009628&#45;&gt;GO:0006970 -->
<g id="edge443" class="edge"><title>GO:0009628&#45;&gt;GO:0006970</title>
<path style="fill:none;stroke:gray;" d="M1666,-871C1656,-861 1646,-849 1638,-840"/>
<polygon style="fill:gray;stroke:gray;" points="1663.45,-873.404 1673,-878 1668.4,-868.454 1663.45,-873.404"/>
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<!-- GO:0009266 -->
<g id="node161" class="node"><title>GO:0009266</title>
<polygon style="fill:white;stroke:white;" points="1497,-804 1497,-846 1555,-846 1555,-804 1497,-804"/>
<polygon style="fill:none;stroke:black;" points="1497,-804 1497,-846 1555,-846 1555,-804 1497,-804"/>
<text text-anchor="middle" x="1526" y="-835.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1526" y="-823.667" style="font-family:Arial;font-size:10px;">temperature</text>
<text text-anchor="middle" x="1526" y="-811.667" style="font-family:Arial;font-size:10px;">stimulus</text>
</g>
<!-- GO:0009628&#45;&gt;GO:0009266 -->
<g id="edge473" class="edge"><title>GO:0009628&#45;&gt;GO:0009266</title>
<path style="fill:none;stroke:gray;" d="M1640,-876C1638,-876 1635,-875 1633,-874 1606,-865 1597,-868 1572,-856 1566,-853 1560,-850 1554,-846"/>
<polygon style="fill:gray;stroke:gray;" points="1639.42,-879.479 1650,-879 1641.43,-872.774 1639.42,-879.479"/>
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<!-- GO:0014070 -->
<g id="node155" class="node"><title>GO:0014070</title>
<polygon style="fill:white;stroke:white;" points="1977,-718 1977,-760 2043,-760 2043,-718 1977,-718"/>
<polygon style="fill:none;stroke:black;" points="1977,-718 1977,-760 2043,-760 2043,-718 1977,-718"/>
<text text-anchor="middle" x="2010" y="-749.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="2010" y="-737.667" style="font-family:Arial;font-size:10px;">organic cyclic</text>
<text text-anchor="middle" x="2010" y="-725.667" style="font-family:Arial;font-size:10px;">substance</text>
</g>
<!-- GO:0014070&#45;&gt;GO:0035094 -->
<g id="edge447" class="edge"><title>GO:0014070&#45;&gt;GO:0035094</title>
<path style="fill:none;stroke:gray;" d="M1997,-709C1989,-689 1979,-664 1972,-646"/>
<polygon style="fill:gray;stroke:gray;" points="1993.74,-710.283 2001,-718 2000.14,-707.44 1993.74,-710.283"/>
</g>
<!-- GO:0010033&#45;&gt;GO:0014070 -->
<g id="edge449" class="edge"><title>GO:0010033&#45;&gt;GO:0014070</title>
<path style="fill:none;stroke:gray;" d="M1999,-800C2001,-787 2004,-773 2006,-760"/>
<polygon style="fill:gray;stroke:gray;" points="1995.53,-799.508 1997,-810 2002.39,-800.881 1995.53,-799.508"/>
</g>
<!-- GO:0043279 -->
<g id="node157" class="node"><title>GO:0043279</title>
<polygon style="fill:white;stroke:white;" points="1885,-724 1885,-754 1943,-754 1943,-724 1885,-724"/>
<polygon style="fill:none;stroke:black;" points="1885,-724 1885,-754 1943,-754 1943,-724 1885,-724"/>
<text text-anchor="middle" x="1914" y="-743.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="1914" y="-731.667" style="font-family:Arial;font-size:10px;">alkaloid</text>
</g>
<!-- GO:0010033&#45;&gt;GO:0043279 -->
<g id="edge455" class="edge"><title>GO:0010033&#45;&gt;GO:0043279</title>
<path style="fill:none;stroke:gray;" d="M1973,-802C1959,-787 1941,-768 1928,-754"/>
<polygon style="fill:gray;stroke:gray;" points="1970.78,-804.779 1980,-810 1976.05,-800.169 1970.78,-804.779"/>
</g>
<!-- GO:0043279&#45;&gt;GO:0035094 -->
<g id="edge453" class="edge"><title>GO:0043279&#45;&gt;GO:0035094</title>
<path style="fill:none;stroke:gray;" d="M1925,-714C1933,-694 1945,-666 1954,-646"/>
<polygon style="fill:gray;stroke:gray;" points="1921.46,-713.415 1921,-724 1927.96,-716.015 1921.46,-713.415"/>
</g>
<!-- GO:0048545 -->
<g id="node158" class="node"><title>GO:0048545</title>
<polygon style="fill:white;stroke:white;" points="2077,-718 2077,-760 2153,-760 2153,-718 2077,-718"/>
<polygon style="fill:none;stroke:black;" points="2077,-718 2077,-760 2153,-760 2153,-718 2077,-718"/>
<text text-anchor="middle" x="2115" y="-749.667" style="font-family:Arial;font-size:10px;">response to</text>
<text text-anchor="middle" x="2115" y="-737.667" style="font-family:Arial;font-size:10px;">steroid hormone</text>
<text text-anchor="middle" x="2115" y="-725.667" style="font-family:Arial;font-size:10px;">stimulus</text>
</g>
<!-- GO:0048545&#45;&gt;GO:0043627 -->
<g id="edge459" class="edge"><title>GO:0048545&#45;&gt;GO:0043627</title>
<path style="fill:none;stroke:gray;" d="M2115,-708C2115,-689 2115,-664 2115,-646"/>
<polygon style="fill:gray;stroke:gray;" points="2111.5,-708 2115,-718 2118.5,-708 2111.5,-708"/>
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<!-- GO:0009725&#45;&gt;GO:0048545 -->
<g id="edge461" class="edge"><title>GO:0009725&#45;&gt;GO:0048545</title>
<path style="fill:none;stroke:gray;" d="M2114,-800C2114,-787 2114,-772 2115,-760"/>
<polygon style="fill:gray;stroke:gray;" points="2110.51,-799.701 2113,-810 2117.48,-800.398 2110.51,-799.701"/>
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<!-- GO:0009719&#45;&gt;GO:0009725 -->
<g id="edge463" class="edge"><title>GO:0009719&#45;&gt;GO:0009725</title>
<path style="fill:none;stroke:gray;" d="M2113,-868C2113,-858 2113,-848 2113,-840"/>
<polygon style="fill:gray;stroke:gray;" points="2109.5,-868 2113,-878 2116.5,-868 2109.5,-868"/>
</g>
<!-- GO:0009266&#45;&gt;GO:0009408 -->
<g id="edge471" class="edge"><title>GO:0009266&#45;&gt;GO:0009408</title>
<path style="fill:none;stroke:gray;" d="M1562,-799C1565,-797 1569,-796 1572,-794 1604,-779 1617,-791 1649,-776 1657,-772 1665,-766 1672,-760"/>
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<!-- GO:0031988 -->
<g id="node162" class="node"><title>GO:0031988</title>
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<polygon style="fill:none;stroke:black;" points="459,-508 459,-538 551,-538 551,-508 459,-508"/>
<text text-anchor="middle" x="505" y="-527.667" style="font-family:Arial;font-size:10px;">membrane&#45;bounded</text>
<text text-anchor="middle" x="505" y="-515.667" style="font-family:Arial;font-size:10px;">vesicle</text>
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<!-- GO:0031988&#45;&gt;GO:0070062 -->
<g id="edge477" class="edge"><title>GO:0031988&#45;&gt;GO:0070062</title>
<path style="fill:none;stroke:gray;" d="M479,-502C470,-493 459,-484 450,-476"/>
<polygon style="fill:gray;stroke:gray;" points="476.9,-504.8 487,-508 481.1,-499.2 476.9,-504.8"/>
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<!-- GO:0031982&#45;&gt;GO:0031988 -->
<g id="edge479" class="edge"><title>GO:0031982&#45;&gt;GO:0031988</title>
<path style="fill:none;stroke:gray;" d="M468,-608C477,-588 491,-557 499,-538"/>
<polygon style="fill:gray;stroke:gray;" points="464.863,-606.44 464,-617 471.26,-609.283 464.863,-606.44"/>
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<!-- GO:0065010&#45;&gt;GO:0070062 -->
<g id="edge483" class="edge"><title>GO:0065010&#45;&gt;GO:0070062</title>
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<!-- GO:0043230&#45;&gt;GO:0065010 -->
<g id="edge487" class="edge"><title>GO:0043230&#45;&gt;GO:0065010</title>
<path style="fill:none;stroke:gray;" d="M379,-600C379,-583 379,-560 379,-544"/>
<polygon style="fill:gray;stroke:gray;" points="375.5,-600 379,-610 382.5,-600 375.5,-600"/>
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<!-- GO:0044421&#45;&gt;GO:0043230 -->
<g id="edge491" class="edge"><title>GO:0044421&#45;&gt;GO:0043230</title>
<path style="fill:none;stroke:gray;" d="M440,-868C427,-813 394,-684 383,-640"/>
<polygon style="fill:gray;stroke:gray;" points="436.774,-869.427 443,-878 443.479,-867.416 436.774,-869.427"/>
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<!-- GO:0048029 -->
<g id="node167" class="node"><title>GO:0048029</title>
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<polygon style="fill:none;stroke:black;" points="107,-724 107,-754 185,-754 185,-724 107,-724"/>
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