Compare GO annotations for EIF2B2 and its Reference Genomes orthologs

Compare GO annotations for EIF2B2 and its orthologs

Possible outliers might be spotted in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, zfish, fly, worm, dicty, dicot, yeast, pombe, ecoli.
Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Red arrows indicate "regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Zfish from Zfin; Fly from Flybase; Worm from Wormbase; Dicot from TAIR; Dicty from Dictybase; Yeast from SGD; Pombe from Sanger; Ecoli from EcoliHub.
Organisms with experimental annotations are indicated: IC, IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Thu Jan 8 13:33:51 2009.

Compare annotations to GO categories for EIF2B2.

Entry indicates that ortholog exists for this gene.
Colored entries indicate experimental annotation.
Parentheses indicate ISS annotation only.

Category	ID	Term	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Molecular Function	GO:0005488	binding	Human	(Mouse)	(Rat)	Chicken	Zfish	(Fly)	Worm	Dicty	X	Yeast	(Pombe)	X
Molecular Function	GO:0030234	enzyme regulator activity	Human	(Mouse)	(Rat)	Chicken	Zfish	Fly	Worm	(Dicty)	X	Yeast	Pombe	X
Molecular Function	GO:0045182	translation regulator activity	Human	Mouse	(Rat)	Chicken	Zfish	(Fly)	Worm	(Dicty)	X	Yeast	(Pombe)	X
Cellular Component	GO:0005623	cell	Human	(Mouse)	(Rat)	Chicken	Zfish	(Fly)	Worm	(Dicty)	X	Yeast	Pombe	X
Cellular Component	GO:0044464	cell part	Human	(Mouse)	(Rat)	Chicken	Zfish	(Fly)	Worm	(Dicty)	X	Yeast	Pombe	X
Cellular Component	GO:0032991	macromolecular complex	Human	(Mouse)	(Rat)	Chicken	Zfish	(Fly)	Worm	(Dicty)	X	Yeast	(Pombe)	X
Cellular Component	GO:0043226	organelle	Human	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	X	Yeast	Pombe	X
Biological Process	GO:0065007	biological regulation	Human	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	(Dicty)	X	Yeast	Pombe	X
Biological Process	GO:0009987	cellular process	Human	Mouse	(Rat)	Chicken	Zfish	(Fly)	Worm	(Dicty)	X	Yeast	(Pombe)	X
Biological Process	GO:0032502	developmental process	Human	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	X	Yeast	Pombe	X
Biological Process	GO:0040007	growth	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	X	Yeast	Pombe	X
Biological Process	GO:0008152	metabolic process	Human	Mouse	(Rat)	Chicken	Zfish	(Fly)	Worm	(Dicty)	X	Yeast	(Pombe)	X
Biological Process	GO:0032501	multicellular organismal process	Human	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	X	Yeast	Pombe	X
Biological Process	GO:0048518	positive regulation of biological process	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	X	Yeast	Pombe	X
Biological Process	GO:0050789	regulation of biological process	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	(Dicty)	X	Yeast	Pombe	X
Biological Process	GO:0000003	reproduction	Human	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	X	Yeast	Pombe	X
Biological Process	GO:0022414	reproductive process	Human	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	X	Yeast	Pombe	X
Biological Process	GO:0050896	response to stimulus	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	X	Yeast	Pombe	X
Biological Process	GO:0048511	rhythmic process	Human	Mouse	(Rat)	Chicken	Zfish	Fly	Worm	Dicty	X	Yeast	Pombe	X

Full set of experimental (and ISS) annotations for EIF2B2

Category	ID	Term	DB Object	Evidence	With_From	Organism	Reference
Molecular Function	GO:0005524	ATP binding	EIF2B2	IDA		Human	PMID:11323413
Molecular Function	GO:0005524	ATP binding	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Molecular Function	GO:0005524	ATP binding	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Molecular Function	GO:0030234	enzyme regulator activity	GCD7	IMP		Yeast	SGD_REF:S000049564\|PMID:9032257
Molecular Function	GO:0030234	enzyme regulator activity	GCD7	IGI	SGD:S000001734\|SGD:S000003315	Yeast	SGD_REF:S000043342\|PMID:8887689
Molecular Function	GO:0030234	enzyme regulator activity	GCD7	IGI	SGD:S000002691	Yeast	SGD_REF:S000045038\|PMID:8164676
Molecular Function	GO:0030234	enzyme regulator activity	GCD7	IPI	SGD:S000001734\|SGD:S000003315	Yeast	SGD_REF:S000043342\|PMID:8887689
Molecular Function	GO:0005525	GTP binding	EIF2B2	IDA		Human	PMID:11323413
Molecular Function	GO:0005525	GTP binding	Eif2b2	ISO	NCBI:NP_055054.1	Mouse	MGI:MGI:2154458
Molecular Function	GO:0005525	GTP binding	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Molecular Function	GO:0005525	GTP binding	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Molecular Function	GO:0005525	GTP binding	eIF2b2	IC	GO:0005085	Dicty	dictyBase_REF:9301\|PMID:12697064
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	EIF2B2	IDA		Human	PMID:11323413
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	EIF2B2	IMP		Human	PMID:15054402
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Eif2b2	ISO	UniProtKB:Q62818	Mouse	MGI:MGI:2154458
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	eIF2b2	ISS	UniProt:P49770	Dicty	dictyBase_REF:9301\|PMID:12697064
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	GCD7	IDA		Yeast	SGD_REF:S000048815\|PMID:8506384
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	GCD7	IPI	SGD:S000005786\|SGD:S000001734\|SGD:S000003315	Yeast	SGD_REF:S000049992\|PMID:8336705
Molecular Function	GO:0005515	protein binding	EIF2B2	IPI	UniProtKB:Q9UI10	Human	PMID:15060152
Molecular Function	GO:0005515	protein binding	Eif2b2	ISO	UniProtKB:Q62818	Mouse	MGI:MGI:2154458
Molecular Function	GO:0005515	protein binding	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Molecular Function	GO:0005515	protein binding	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Molecular Function	GO:0003743	translation initiation factor activity	EIF2B2	IDA		Human	PMID:16289705
Molecular Function	GO:0003743	translation initiation factor activity	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Molecular Function	GO:0003743	translation initiation factor activity	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Molecular Function	GO:0003743	translation initiation factor activity	eIF2B-beta	ISS		Fly	FB:FBrf0071734
Molecular Function	GO:0003743	translation initiation factor activity	eIF2B-beta	ISS		Fly	FB:FBrf0129923\|PMID:10908586
Molecular Function	GO:0003743	translation initiation factor activity	eIF2B-beta	ISS	SGD:S0004282	Fly	FB:FBrf0132369\|PMID:11060303
Molecular Function	GO:0003743	translation initiation factor activity	eIF2b2	ISS	UniProt:P49770	Dicty	dictyBase_REF:9301\|PMID:12697064
Molecular Function	GO:0003743	translation initiation factor activity	GCD7	IPI	SGD:S000003315\|SGD:S000001734\|SGD:S000005786	Yeast	SGD_REF:S000049992\|PMID:8336705
Molecular Function	GO:0003743	translation initiation factor activity	GCD7	IGI	SGD:S000001734	Yeast	SGD_REF:S000049992\|PMID:8336705
Molecular Function	GO:0003743	translation initiation factor activity	SPAC343.14c	ISS	SGD:S000004282	Pombe	PMID:17072883
Cellular Component	GO:0005737	cytoplasm	EIF2B2	IDA		Human	PMID:11323413
Cellular Component	GO:0005737	cytoplasm	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Cellular Component	GO:0005737	cytoplasm	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Cellular Component	GO:0005829	cytosol	eIF2B-beta	ISS		Fly	FB:FBrf0071734
Cellular Component	GO:0005829	cytosol	eIF2B-beta	ISS		Fly	FB:FBrf0129923\|PMID:10908586
Cellular Component	GO:0005829	cytosol	SPAC343.14c	IDA		Pombe	PMID:16823372
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	EIF2B2	IDA		Human	PMID:11323413
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	EIF2B2	IDA		Human	PMID:15060152
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	Eif2b2	ISO	UniProtKB:Q62818	Mouse	MGI:MGI:2154458
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	eIF2B-beta	ISS		Fly	FB:FBrf0071734
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	eIF2B-beta	ISS		Fly	FB:FBrf0129923\|PMID:10908586
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	eIF2B-beta	ISS	SGD:S0004282	Fly	FB:FBrf0132369\|PMID:11060303
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	eIF2b2	ISS	UniProt:P49770	Dicty	dictyBase_REF:10155
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	GCD7	IDA		Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	GCD7	IPI	SGD:S000003315\|SGD:S000005786\|SGD:S000001734	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	GCD7	IPI	SGD:S000005786	Yeast	SGD_REF:S000048815\|PMID:8506384
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	GCD7	IDA		Yeast	SGD_REF:S000048815\|PMID:8506384
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	GCD7	IGI	SGD:S000001734	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	GCD7	IMP		Yeast	SGD_REF:S000048683\|PMID:8441423
Cellular Component	GO:0005851	eukaryotic translation initiation factor 2B complex	SPAC343.14c	ISS	SGD:S000004282	Pombe	PMID:17072883
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	GCD7	IPI	SGD:S000005786\|SGD:S000003315\|SGD:S000001734	Yeast	SGD_REF:S000049992\|PMID:8336705
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	GCD7	IDA		Yeast	SGD_REF:S000048815\|PMID:8506384
Cellular Component	GO:0005739	mitochondrion	GCD7	IDA		Yeast	SGD_REF:S000117178\|PMID:16823961
Cellular Component	GO:0005739	mitochondrion	GCD7	IDA		Yeast	SGD_REF:S000075100\|PMID:14576278
Cellular Component	GO:0005634	nucleus	EIF2B2	IDA		Human	PMID:18029348
Cellular Component	GO:0005634	nucleus	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Biological Process	GO:0010171	body morphogenesis	Y47H9C.7	IMP	WB:WBRNAi00026746\|WB:WBPhenotype:0000583	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0010171	body morphogenesis	Y47H9C.7	IMP	WB:WBRNAi00072741\|WB:WBPhenotype:0000583	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0010171	body morphogenesis	Y47H9C.7	IMP	WB:WBRNAi00072742\|WB:WBPhenotype:0000583	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0010171	body morphogenesis	Y47H9C.7	IMP	WB:WBRNAi00075006\|WB:WBPhenotype:0000583	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0010171	body morphogenesis	Y47H9C.7	IMP	WB:WBRNAi00075009\|WB:WBPhenotype:0000583	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0051716	cellular response to stimulus	EIF2B2	IDA		Human	PMID:8626696
Biological Process	GO:0051716	cellular response to stimulus	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Biological Process	GO:0051716	cellular response to stimulus	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Biological Process	GO:0007417	central nervous system development	EIF2B2	IMP		Human	PMID:15776425
Biological Process	GO:0007417	central nervous system development	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Biological Process	GO:0007417	central nervous system development	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	Y47H9C.7	IMP	WB:WBRNAi00004668\|WB:WBPhenotype:0000050	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	Y47H9C.7	IMP	WB:WBRNAi00056852\|WB:WBPhenotype:0000050	Worm	WB:WBPaper00025054\|PMID:15791247
Biological Process	GO:0040007	growth	Y47H9C.7	IMP	WB:WBRNAi00026746\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0040007	growth	Y47H9C.7	IMP	WB:WBRNAi00072741\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0040007	growth	Y47H9C.7	IMP	WB:WBRNAi00072742\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0040007	growth	Y47H9C.7	IMP	WB:WBRNAi00075006\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0040007	growth	Y47H9C.7	IMP	WB:WBRNAi00075009\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0042552	myelination	EIF2B2	IMP		Human	PMID:14566705
Biological Process	GO:0042552	myelination	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Biological Process	GO:0042552	myelination	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Biological Process	GO:0002119	nematode larval development	Y47H9C.7	IMP	WB:WBRNAi00026746\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00006395\|PMID:14551910
Biological Process	GO:0002119	nematode larval development	Y47H9C.7	IMP	WB:WBRNAi00072741\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0002119	nematode larval development	Y47H9C.7	IMP	WB:WBRNAi00072742\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0002119	nematode larval development	Y47H9C.7	IMP	WB:WBRNAi00075006\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0002119	nematode larval development	Y47H9C.7	IMP	WB:WBRNAi00075009\|WB:WBPhenotype:0000059	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0014003	oligodendrocyte development	EIF2B2	IMP		Human	PMID:15217090
Biological Process	GO:0014003	oligodendrocyte development	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Biological Process	GO:0014003	oligodendrocyte development	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Biological Process	GO:0001541	ovarian follicle development	EIF2B2	IMP		Human	PMID:15507143
Biological Process	GO:0001541	ovarian follicle development	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Biological Process	GO:0001541	ovarian follicle development	Eif2b2	ISS	RGD:731256	Rat	RGD:1624291
Biological Process	GO:0040010	positive regulation of growth rate	Y47H9C.7	IMP	WB:WBRNAi00004668\|WB:WBPhenotype:0000031	Worm	WB:WBPaper00004402\|PMID:11099033
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Y47H9C.7	IMP	WB:WBRNAi00075003\|WB:WBPhenotype:0000229	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Y47H9C.7	IMP	WB:WBRNAi00075005\|WB:WBPhenotype:0000229	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0040018	positive regulation of multicellular organism growth	Y47H9C.7	IMP	WB:WBRNAi00075008\|WB:WBPhenotype:0000229	Worm	WB:WBPaper00029258\|PMID:17417969
Biological Process	GO:0006446	regulation of translational initiation	eIF2b2	ISS	UniProt:P49770	Dicty	dictyBase_REF:9301\|PMID:12697064
Biological Process	GO:0006446	regulation of translational initiation	GCD7	IGI	SGD:S000002691	Yeast	SGD_REF:S000045038\|PMID:8164676
Biological Process	GO:0006446	regulation of translational initiation	GCD7	IMP		Yeast	SGD_REF:S000049564\|PMID:9032257
Biological Process	GO:0006446	regulation of translational initiation	GCD7	IGI	SGD:S000003315\|SGD:S000001734	Yeast	SGD_REF:S000043342\|PMID:8887689
Biological Process	GO:0006446	regulation of translational initiation	GCD7	IDA		Yeast	SGD_REF:S000048815\|PMID:8506384
Biological Process	GO:0006446	regulation of translational initiation	GCD7	IPI	SGD:S000003315\|SGD:S000001734	Yeast	SGD_REF:S000043342\|PMID:8887689
Biological Process	GO:0009749	response to glucose stimulus	EIF2B2	ISS	UniProtKB:Q62818	Human	UniProtKB:P49770
Biological Process	GO:0009749	response to glucose stimulus	Eif2b2	IDA		Rat	RGD:null
Biological Process	GO:0009408	response to heat	EIF2B2	ISS	UniProtKB:Q62818	Human	UniProtKB:P49770
Biological Process	GO:0009408	response to heat	Eif2b2	IDA		Rat	RGD:null
Biological Process	GO:0043434	response to peptide hormone stimulus	EIF2B2	ISS	UniProtKB:Q62818	Human	UniProtKB:P49770
Biological Process	GO:0043434	response to peptide hormone stimulus	Eif2b2	IDA		Rat	RGD:null
Biological Process	GO:0006413	translational initiation	Eif2b2	ISS	UniProtKB:P49770	Rat	RGD:1600115
Biological Process	GO:0006413	translational initiation	eIF2B-beta	ISS		Fly	FB:FBrf0071734
Biological Process	GO:0006413	translational initiation	eIF2B-beta	ISS		Fly	FB:FBrf0129923\|PMID:10908586
Biological Process	GO:0006413	translational initiation	eIF2B-beta	ISS	SGD:S0004282	Fly	FB:FBrf0132369\|PMID:11060303
Biological Process	GO:0006413	translational initiation	SPAC343.14c	ISS	SGD:S000004282	Pombe	PMID:17072883

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)