Compare GO annotations for CLN3 and its orthologs

A summary/comparison table of the GOSlim categories is provided below.
A table of the annotations represented in this image is provided below.


Compare annotations to generic GOSlim branches
Category ID Term Human Mouse Rat Worm Fly Dicty Chicken Zfin Tair Yeast Pombe Ecoli
Molecular FunctionGO:0005488bindingX(Mouse)(Rat)XXXXXXXXX
Molecular FunctionGO:0003674molecular_functionX(Mouse)(Rat)XXXXXXXXX
Molecular FunctionGO:0005515protein bindingXMouseRatXXXXXXXXX
Cellular ComponentGO:0005623cell(Human)(Mouse)(Rat)XX(Dicty)XXX(Yeast)(Pombe)X
Cellular ComponentGO:0005575cellular_component(Human)(Mouse)(Rat)XX(Dicty)XXX(Yeast)(Pombe)X
Cellular ComponentGO:0005737cytoplasmHuman(Mouse)RatXXXXXX(Yeast)(Pombe)X
Cellular ComponentGO:0016023cytoplasmic membrane-bound vesicle(Human)X(Rat)XXXXXXXXX
Cellular ComponentGO:0005783endoplasmic reticulumHumanXRatXXXXXXXPombeX
Cellular ComponentGO:0005768endosome(Human)(Mouse)RatXXXXXXXXX
Cellular ComponentGO:0005794Golgi apparatusHumanXRatXXXXXXXXX
Cellular ComponentGO:0005622intracellular(Human)(Mouse)(Rat)XXXXXX(Yeast)(Pombe)X
Cellular ComponentGO:0005764lysosomeHumanMouseRatXXXXXXXXX
Cellular ComponentGO:0005634nucleusHumanXRatXXXXXXXXX
Cellular ComponentGO:0043226organelle(Human)(Mouse)(Rat)XXXXXX(Yeast)(Pombe)X
Cellular ComponentGO:0005886plasma membraneHumanXRatXXXXXXXXX
Cellular ComponentGO:0005773vacuole(Human)(Mouse)(Rat)XXXXXX(Yeast)(Pombe)X
Biological ProcessGO:0006519amino acid and derivative metabolic processX(Mouse)XXXXXXXXXX
Biological ProcessGO:0007610behaviorX(Mouse)X(Worm)XXXXXXXX
Biological ProcessGO:0008150biological_process(Human)(Mouse)(Rat)(Worm)XXXXX(Yeast)(Pombe)X
Biological ProcessGO:0007154cell communicationX(Mouse)XXXXXXXXXX
Biological ProcessGO:0008219cell death(Human)(Mouse)(Rat)XXXXXXXXX
Biological ProcessGO:0030154cell differentiation(Human)(Mouse)(Rat)XXXXXXXXX
Biological ProcessGO:0007267cell-cell signalingX(Mouse)XXXXXXXXXX
Biological ProcessGO:0016043cellular component organization and biogenesis(Human)(Mouse)(Rat)XXXXXXX(Pombe)X
Biological ProcessGO:0019725cellular homeostasis(Human)(Mouse)(Rat)XXXXXX(Yeast)(Pombe)X
Biological ProcessGO:0016265death(Human)(Mouse)(Rat)XXXXXXXXX
Biological ProcessGO:0009790embryonic developmentXXX(Worm)XXXXXXXX
Biological ProcessGO:0006629lipid metabolic process(Human)X(Rat)XXXXXXXXX
Biological ProcessGO:0008152metabolic process(Human)(Mouse)(Rat)XXXXXXXXX
Biological ProcessGO:0007275multicellular organismal developmentXXX(Worm)XXXXXXXX
Biological ProcessGO:0006996organelle organization and biogenesis(Human)(Mouse)(Rat)XXXXXXX(Pombe)X
Biological ProcessGO:0044238primary metabolic process(Human)(Mouse)(Rat)XXXXXXXXX
Biological ProcessGO:0019538protein metabolic process(Human)(Mouse)(Rat)XXXXXXXXX
Biological ProcessGO:0006464protein modification processX(Mouse)XXXXXXXXXX
Biological ProcessGO:0050789regulation of biological process(Human)(Mouse)(Rat)(Worm)XXXXXXXX
Biological ProcessGO:0000003reproductionXXX(Worm)XXXXXXXX
Biological ProcessGO:0007165signal transductionX(Mouse)XXXXXXXXXX
Biological ProcessGO:0006810transport(Human)(Mouse)(Rat)XXXXXX(Yeast)(Pombe)X


Full set of experimental (and ISS) annotations
Category ID Term DB Object Evidence Organism Reference
Molecular FunctionGO:0048306calcium-dependent protein bindingCln3IPIMouseMGI:MGI:3697749|PMID:17189291
Molecular FunctionGO:0005515protein bindingCln3IPIMouseMGI:MGI:3697749|PMID:17189291
Molecular FunctionGO:0005515protein bindingCln3ISSRatRGD:1600115
Cellular ComponentGO:0005776autophagic vacuoleCln3IDAMouseMGI:MGI:3690270|PMID:16714284
Cellular ComponentGO:0005901caveolaCLN3_HUMANIDAHumanPMID:15240864
Cellular ComponentGO:0005901caveolaCln3ISSRatRGD:1598669|PMID:15240864
Cellular ComponentGO:0005901caveolaCln3ISSRatRGD:1600115
Cellular ComponentGO:0005737cytoplasmCLN3_HUMANIDAHumanPMID:10191116
Cellular ComponentGO:0005737cytoplasmCln3ISSRatRGD:1600115
Cellular ComponentGO:0044433cytoplasmic vesicle partCln3IDAMouseMGI:MGI:3697749|PMID:17189291
Cellular ComponentGO:0005769early endosomeCLN3_HUMANIDAHumanPMID:15240864
Cellular ComponentGO:0005769early endosomeCln3IDAMouseMGI:MGI:3527911|PMID:15588329
Cellular ComponentGO:0005769early endosomeCln3ISSRatRGD:1600115
Cellular ComponentGO:0005783endoplasmic reticulumCLN3_HUMANIDAHumanPMID:10191111
Cellular ComponentGO:0005783endoplasmic reticulumCln3ISSRatRGD:1600115
Cellular ComponentGO:0005783endoplasmic reticulumbtn1IDAPombePMID:16823372
Cellular ComponentGO:0005768endosomeCln3ISSRatRGD:1598669|PMID:15240864
Cellular ComponentGO:0005794Golgi apparatusCLN3_HUMANIDAHumanPMID:15240864
Cellular ComponentGO:0005794Golgi apparatusCln3ISSRatRGD:1598669|PMID:15240864
Cellular ComponentGO:0005794Golgi apparatusCln3ISSRatRGD:1600115
Cellular ComponentGO:0000139Golgi membraneCLN3_HUMANIDAHumanPMID:10191111
Cellular ComponentGO:0000139Golgi membraneCLN3_HUMANIDAHumanPMID:9949212
Cellular ComponentGO:0000139Golgi membraneCln3ISSRatRGD:1600115
Cellular ComponentGO:0005795Golgi stackCLN3_HUMANIDAHumanPMID:15240864
Cellular ComponentGO:0005795Golgi stackCln3ISSRatRGD:1600115
Cellular ComponentGO:0030176integral to endoplasmic reticulum membraneCLN3_HUMANIDAHumanPMID:12706816
Cellular ComponentGO:0030176integral to endoplasmic reticulum membraneCln3ISSRatRGD:1600115
Cellular ComponentGO:0016021integral to membraneCLN3_HUMANIDAHumanPMID:10191112
Cellular ComponentGO:0016021integral to membraneCln3ISSRatRGD:1580654
Cellular ComponentGO:0016021integral to membraneCln3ISSRatRGD:1600115
Cellular ComponentGO:0016021integral to membranecln3ISSDictyDDB_REF:10155
Cellular ComponentGO:0005770late endosomeCln3IDAMouseMGI:MGI:3527911|PMID:15588329
Cellular ComponentGO:0045121lipid raftCLN3_HUMANIDAHumanPMID:15240864
Cellular ComponentGO:0045121lipid raftCln3ISSRatRGD:1598669|PMID:15240864
Cellular ComponentGO:0045121lipid raftCln3ISSRatRGD:1600115
Cellular ComponentGO:0005764lysosomeCLN3_HUMANIDAHumanPMID:10924275
Cellular ComponentGO:0005764lysosomeCLN3_HUMANIDAHumanPMID:9384607
Cellular ComponentGO:0005764lysosomeCln3IDAMouseMGI:MGI:3690270|PMID:16714284
Cellular ComponentGO:0005764lysosomeCln3IDAMouseMGI:MGI:3527911|PMID:15588329
Cellular ComponentGO:0005764lysosomeCln3ISSRatRGD:1549688|PMID:14622109
Cellular ComponentGO:0005764lysosomeCln3ISSRatRGD:1600115
Cellular ComponentGO:0005624membrane fractionCLN3_HUMANIDAHumanPMID:12134079
Cellular ComponentGO:0005624membrane fractionCln3ISSRatRGD:1600115
Cellular ComponentGO:0000329membrane of vacuole with cell cycle-correlated morphologybtn1IDAPombePMID:16291725
Cellular ComponentGO:0043005neuron projectionCLN3_HUMANIDAHumanPMID:10332042
Cellular ComponentGO:0043005neuron projectionCln3ISSRatRGD:1600115
Cellular ComponentGO:0005634nucleusCLN3_HUMANIDAHumanPMID:10191116
Cellular ComponentGO:0005634nucleusCln3ISSRatRGD:1600115
Cellular ComponentGO:0005886plasma membraneCLN3_HUMANIDAHumanPMID:15240864
Cellular ComponentGO:0005886plasma membraneCLN3_HUMANIDAHumanPMID:10191116
Cellular ComponentGO:0005886plasma membraneCln3ISSRatRGD:1598669|PMID:15240864
Cellular ComponentGO:0005886plasma membraneCln3ISSRatRGD:1600115
Cellular ComponentGO:0008021synaptic vesicleCLN3_HUMANIDAHumanPMID:11590129
Cellular ComponentGO:0008021synaptic vesicleCLN3_HUMANIDAHumanPMID:10332042
Cellular ComponentGO:0008021synaptic vesicleCln3ISSRatRGD:1600115
Cellular ComponentGO:0005802trans-Golgi networkCLN3_HUMANIDAHumanPMID:15240864
Cellular ComponentGO:0005802trans-Golgi networkCln3ISSRatRGD:1600115
Cellular ComponentGO:0000324vacuole, cell cycle-correlated morphologyYHC3IDAYeastSGD_REF:S000046600|PMID:9753630
Cellular ComponentGO:0000324vacuole, cell cycle-correlated morphologyYHC3IDAYeastSGD_REF:S000043786|PMID:10319861
Cellular ComponentGO:0000324vacuole, cell cycle-correlated morphologybtn1ISSPombeGOC:unpublished
Biological ProcessGO:0006520amino acid metabolic processCln3IMPMouseMGI:MGI:3616748|PMID:12763292
Biological ProcessGO:0006865amino acid transportCln3IMPMouseMGI:MGI:3653287|PMID:16412658
Biological ProcessGO:0042987amyloid precursor protein catabolic processCLN3_HUMANIDAHumanPMID:10924275
Biological ProcessGO:0042987amyloid precursor protein catabolic processCln3ISSRatRGD:1600115
Biological ProcessGO:0015809arginine transportCLN3_HUMANIDAHumanPMID:16251196
Biological ProcessGO:0015809arginine transportCln3ISSRatRGD:1600115
Biological ProcessGO:0015809arginine transportYHC3IMPYeastSGD_REF:S000075209|PMID:14660799
Biological ProcessGO:0015809arginine transportYHC3IGIYeastSGD_REF:S000075209|PMID:14660799
Biological ProcessGO:0008306associative learningCln3IMPMouseMGI:MGI:3580037|PMID:15885820
Biological ProcessGO:0000046autophagic vacuole fusionCln3IMPMouseMGI:MGI:3690270|PMID:16714284
Biological ProcessGO:0000917barrier septum formationbtn1IMPPombePMID:16291725
Biological ProcessGO:0015802basic amino acid transportYHC3IMPYeastSGD_REF:S000075209|PMID:14660799
Biological ProcessGO:0015802basic amino acid transportbtn1ISSPombeGOC:unpublished
Biological ProcessGO:0051480cytosolic calcium ion homeostasisCln3IDAMouseMGI:MGI:3697749|PMID:17189291
Biological ProcessGO:0008340determination of adult life spancln-3.1IMPWormWB:WBPaper00027030|PMID:16435200
Biological ProcessGO:0008340determination of adult life spancln-3.1IGIWormWB:WBPaper00027030|PMID:16435200
Biological ProcessGO:0008340determination of adult life spancln-3.2IGIWormWB:WBPaper00027030|PMID:16435200
Biological ProcessGO:0008340determination of adult life spancln-3.3IGIWormWB:WBPaper00027030|PMID:16435200
Biological ProcessGO:0009792embryonic development ending in birth or egg hatchingcln-3.2IMPWormWB:WBPaper00005599|PMID:12445391
Biological ProcessGO:0006681galactosylceramide metabolic processCLN3_HUMANIMPHumanPMID:15240864
Biological ProcessGO:0006681galactosylceramide metabolic processCln3ISSRatRGD:1600115
Biological ProcessGO:0001575globoside metabolic processCLN3_HUMANIMPHumanPMID:15240864
Biological ProcessGO:0001575globoside metabolic processCln3ISSRatRGD:1600115
Biological ProcessGO:0006678glucosylceramide metabolic processCLN3_HUMANIMPHumanPMID:15240864
Biological ProcessGO:0006678glucosylceramide metabolic processCln3ISSRatRGD:1600115
Biological ProcessGO:0035235ionotropic glutamate receptor signaling pathwayCln3IMPMouseMGI:MGI:3653554|PMID:16483786
Biological ProcessGO:0045324late endosome to vacuole transportbtn1IMPPombePMID:16291725
Biological ProcessGO:0007042lysosomal lumen acidificationCLN3_HUMANIMPHumanPMID:11722572
Biological ProcessGO:0007042lysosomal lumen acidificationCln3ISSRatRGD:1600115
Biological ProcessGO:0007040lysosome organization and biogenesisCln3IMPMouseMGI:MGI:1337525|PMID:10191119
Biological ProcessGO:0007040lysosome organization and biogenesisCln3IMPMouseMGI:MGI:1343910|PMID:10440905
Biological ProcessGO:0007040lysosome organization and biogenesisCln3IMPMouseMGI:MGI:1346962|PMID:10527801
Biological ProcessGO:0007040lysosome organization and biogenesisCln3IMPMouseMGI:MGI:3527911|PMID:15588329
Biological ProcessGO:0016236macroautophagyCln3IMPMouseMGI:MGI:3690270|PMID:16714284
Biological ProcessGO:0016044membrane organization and biogenesisCln3IMPMouseMGI:MGI:3527911|PMID:15588329
Biological ProcessGO:0043066negative regulation of apoptosisCLN3_HUMANIMPHumanPMID:15240864
Biological ProcessGO:0043066negative regulation of apoptosisCln3ISSRatRGD:1600115
Biological ProcessGO:0016242negative regulation of macroautophagyCln3IMPMouseMGI:MGI:3690270|PMID:16714284
Biological ProcessGO:0043524negative regulation of neuron apoptosisCln3IDAMouseMGI:MGI:3697749|PMID:17189291
Biological ProcessGO:0045861negative regulation of proteolysisCln3IMPMouseMGI:MGI:1346962|PMID:10527801
Biological ProcessGO:0042133neurotransmitter metabolic processCln3IMPMouseMGI:MGI:3616353|PMID:16239221
Biological ProcessGO:0016485protein processingCln3IMPMouseMGI:MGI:3527911|PMID:15588329
Biological ProcessGO:0006898receptor-mediated endocytosisCLN3_HUMANIMPHumanPMID:15471887
Biological ProcessGO:0006898receptor-mediated endocytosisCln3ISSRatRGD:1600115
Biological ProcessGO:0001508regulation of action potentialCln3IMPMouseMGI:MGI:3653287|PMID:16412658
Biological ProcessGO:0050885regulation of balanceCln3IMPMouseMGI:MGI:3653554|PMID:16483786
Biological ProcessGO:0051453regulation of cellular pHCLN3_HUMANIDAHumanPMID:10924275
Biological ProcessGO:0051453regulation of cellular pHCln3ISSRatRGD:1600115
Biological ProcessGO:0051453regulation of cellular pHYHC3IMPYeastSGD_REF:S000043786|PMID:10319861
Biological ProcessGO:0051453regulation of cellular pHYHC3IMPYeastSGD_REF:S000114207|PMID:16423829
Biological ProcessGO:0051453regulation of cellular pHYHC3IMPYeastSGD_REF:S000041784|PMID:10191121
Biological ProcessGO:0046662regulation of ovipositioncln-3.2IMPWormWB:WBPaper00027030|PMID:16435200
Biological ProcessGO:0046662regulation of ovipositioncln-3.3IGIWormWB:WBPaper00027030|PMID:16435200
Biological ProcessGO:0006684sphingomyelin metabolic processCLN3_HUMANIMPHumanPMID:15240864
Biological ProcessGO:0006684sphingomyelin metabolic processCln3ISSRatRGD:1600115
Biological ProcessGO:0007035vacuolar acidificationbtn1IMPPombePMID:16291725
Biological ProcessGO:0007035vacuolar acidificationbtn1IGIPombePMID:16291725
Biological ProcessGO:0007033vacuole organization and biogenesisbtn1IMPPombePMID:16291725

Gene Ontology Evidence Code Abbreviations:

  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Not recorded (appears in some legacy annotations)