Compare GO annotations for POLA and its orthologs




Compare annotations to GO categories for POLA.
Category ID Term Human Mouse Rat Chicken Zfish Fly Worm Dicty Dicot Yeast Pombe Ecoli
Molecular FunctionGO:0005488bindingHumanMouseRat(Chicken)ZfishFlyWorm(Dicty)DicotYeastPombeX
Molecular FunctionGO:0003824catalytic activityHumanMouseRat(Chicken)ZfishFly(Worm)(Dicty)DicotYeastPombeX
Cellular ComponentGO:0005623cellHumanMouseRat(Chicken)ZfishFly(Worm)(Dicty)DicotYeastPombeX
Cellular ComponentGO:0044464cell partHumanMouseRat(Chicken)ZfishFly(Worm)(Dicty)DicotYeastPombeX
Cellular ComponentGO:0031975envelopeHumanMouse(Rat)(Chicken)ZfishFlyWormDictyDicotYeastPombeX
Cellular ComponentGO:0032991macromolecular complexHumanMouseRat(Chicken)ZfishFlyWorm(Dicty)DicotYeastPombeX
Cellular ComponentGO:0031974membrane-enclosed lumenHumanMouse(Rat)(Chicken)ZfishFlyWormDictyDicotYeastPombeX
Cellular ComponentGO:0043226organelleHumanMouseRat(Chicken)ZfishFly(Worm)(Dicty)DicotYeastPombeX
Cellular ComponentGO:0044422organelle partHumanMouseRat(Chicken)ZfishFlyWorm(Dicty)DicotYeastPombeX
Biological ProcessGO:0065007biological regulationHumanMouseRatChickenZfishFlyWormDictyDicotYeastPombeX
Biological ProcessGO:0009987cellular processHumanMouseRat(Chicken)ZfishFlyWorm(Dicty)DicotYeastPombeX
Biological ProcessGO:0032502developmental processHumanMouseRatChickenZfishFlyWormDictyDicotYeastPombeX
Biological ProcessGO:0051234establishment of localizationHumanMouseRatChickenZfishFlyWormDictyDicotYeastPombeX
Biological ProcessGO:0051179localizationHumanMouseRatChickenZfishFlyWormDictyDicotYeastPombeX
Biological ProcessGO:0008152metabolic processHumanMouseRat(Chicken)ZfishFly(Worm)(Dicty)DicotYeastPombeX
Biological ProcessGO:0032501multicellular organismal processHumanMouseRatChickenZfishFlyWormDictyDicotYeastPombeX
Biological ProcessGO:0048519negative regulation of biological processHumanMouseRatChickenZfishFlyWormDictyDicotYeastPombeX
Biological ProcessGO:0050789regulation of biological processHumanMouseRatChickenZfishFlyWormDictyDicotYeastPombeX
Biological ProcessGO:0000003reproductionHumanMouseRatChickenZfishFlyWormDictyDicotYeastPombeX
Biological ProcessGO:0022414reproductive processHumanMouseRatChickenZfishFlyWormDictyDicotYeastPombeX
Biological ProcessGO:0050896response to stimulusHumanMouse(Rat)(Chicken)ZfishFlyWorm(Dicty)DicotYeastPombeX


Full set of experimental (and ISS) annotations for POLA
Category ID Term DB Object Evidence With_From Organism Reference
Molecular FunctionGO:0003682chromatin bindingPOLA1IDAHumanPMID:16762037
Molecular FunctionGO:0003682chromatin bindingPola1ISSUniProtKB:P09884RatRGD:1600115
Molecular FunctionGO:0003682chromatin bindingQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Molecular FunctionGO:0003677DNA bindingPOLA1IDAHumanPMID:16762037
Molecular FunctionGO:0003677DNA bindingPola1ISSUniProtKB:P09884RatRGD:1600115
Molecular FunctionGO:0003677DNA bindingQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Molecular FunctionGO:0003677DNA bindingpolA1ISSInterPro:IPR001098DictydictyBase_REF:10155
Molecular FunctionGO:0003896DNA primase activityPOLA1IDAHumanPMID:2175912
Molecular FunctionGO:0003896DNA primase activityPola1ISSUniProtKB:P09884RatRGD:1600115
Molecular FunctionGO:0003896DNA primase activityQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Molecular FunctionGO:0003896DNA primase activitypolA1ISSUniProt:P09884DictydictyBase_REF:10155
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPOLA1IMPHumanPMID:4084590
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPOLA1IDAHumanPMID:3359994
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPOLA1IDAHumanPMID:893425
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPola1IDAMouseMGI:MGI:1203906|PMID:9584195
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPola1IDAMouseMGI:MGI:64718|PMID:8106564
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPola1IDARatRGD:724599|PMID:7354082
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPola1IMPRatRGD:1580606|PMID:8576284
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPola1ISSUniProtKB:P09884RatRGD:1600115
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityY47D3A.29ISSUniProtKB:P09884WormWB:WBPaper00003297
Molecular FunctionGO:0003887DNA-directed DNA polymerase activitypolA1ISSInterPro:IPR001098DictydictyBase_REF:10155
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPOL1IDAYeastSGD_REF:S000064604|PMID:3907855
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPOL1IDAYeastSGD_REF:S000116439|PMID:1704371
Molecular FunctionGO:0003887DNA-directed DNA polymerase activityPOL1IDAYeastSGD_REF:S000064605|PMID:3888995
Molecular FunctionGO:0003887DNA-directed DNA polymerase activitypol1IGISGD:S000005046PombePMID:8423854
Molecular FunctionGO:0003690double-stranded DNA bindingPola1IDARatRGD:1580605|PMID:7670930
Molecular FunctionGO:0000166nucleotide bindingPOLA1IDAHumanPMID:3139084
Molecular FunctionGO:0000166nucleotide bindingQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Molecular FunctionGO:0000166nucleotide bindingpolA1ISSUniProt:P09884DictydictyBase_REF:10155
Molecular FunctionGO:0005515protein bindingPOLA1IPIUniProtKB:P33993HumanPMID:10518787
Molecular FunctionGO:0005515protein bindingPOLA1IPIUniProtKB:P06750HumanPMID:2243771
Molecular FunctionGO:0005515protein bindingPOLA1IPIUniProtKB:P06400HumanPMID:9395244
Molecular FunctionGO:0005515protein bindingPOLA1IPIUniProtKB:P81460HumanPMID:2243771
Molecular FunctionGO:0005515protein bindingPOLA1IPIUniProtKB:P29558-1HumanPMID:10869558
Molecular FunctionGO:0005515protein bindingPOLA1IPIUniProtKB:O75419HumanPMID:10518787
Molecular FunctionGO:0005515protein bindingPOLA1IPIUniProtKB:P09874HumanPMID:9518481
Molecular FunctionGO:0005515protein bindingPOLA1IPIUniProtKB:Q14683HumanPMID:16438930
Molecular FunctionGO:0005515protein bindingPOLA1IPIUniProtKB:P27694HumanPMID:1311258
Molecular FunctionGO:0005515protein bindingPola1ISSUniProtKB:P09884RatRGD:1600115
Molecular FunctionGO:0005515protein bindingQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Molecular FunctionGO:0005515protein bindingpol1IPIGeneDB_Spombe:SPBC1734.02cPombePMID:15579205
Molecular FunctionGO:0005515protein bindingpol1IPIGeneDB_Spombe:SPAPB1E7.02cPombePMID:15643072
Molecular FunctionGO:0046982protein heterodimerization activityPola1IPIUniProtKB:P33611MouseMGI:MGI:1203906|PMID:9584195
Molecular FunctionGO:0017076purine nucleotide bindingPola1IMPRatRGD:1580605|PMID:7670930
Molecular FunctionGO:0019103pyrimidine nucleotide bindingPola1IMPRatRGD:1580605|PMID:7670930
Cellular ComponentGO:0005658alpha DNA polymerase:primase complexPOLA1IDAHumanPMID:2175912
Cellular ComponentGO:0005658alpha DNA polymerase:primase complexPola1IDAMouseMGI:MGI:1203906|PMID:9584195
Cellular ComponentGO:0005658alpha DNA polymerase:primase complexPola1IDARatRGD:1580605|PMID:7670930
Cellular ComponentGO:0005658alpha DNA polymerase:primase complexPola1ISSUniProtKB:P09884RatRGD:1600115
Cellular ComponentGO:0005658alpha DNA polymerase:primase complexQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Cellular ComponentGO:0005658alpha DNA polymerase:primase complexpolA1ISSUniProt:P09884DictydictyBase_REF:10155
Cellular ComponentGO:0005658alpha DNA polymerase:primase complexPOL1IDAYeastSGD_REF:S000064605|PMID:3888995
Cellular ComponentGO:0005658alpha DNA polymerase:primase complexpol1IGISGD:S000005046PombePMID:8423854
Cellular ComponentGO:0000785chromatinPOLA1IDAHumanPMID:9815285
Cellular ComponentGO:0000785chromatinPola1ISSUniProtKB:P09884RatRGD:1600115
Cellular ComponentGO:0000785chromatinQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Cellular ComponentGO:0005737cytoplasmPOLA1IDAHumanPMID:18029348
Cellular ComponentGO:0005739mitochondrionPOL1IDAYeastSGD_REF:S000117178|PMID:16823961
Cellular ComponentGO:0005635nuclear envelopePOLA1IDAHumanPMID:9518481
Cellular ComponentGO:0005635nuclear envelopePola1ISSUniProtKB:P09884RatRGD:1600115
Cellular ComponentGO:0005635nuclear envelopeQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Cellular ComponentGO:0016363nuclear matrixPOLA1IDAHumanPMID:1903085
Cellular ComponentGO:0016363nuclear matrixPola1ISSUniProtKB:P09884RatRGD:1600115
Cellular ComponentGO:0016363nuclear matrixQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Cellular ComponentGO:0005730nucleolusPOLA1IDAHumanPMID:9518481
Cellular ComponentGO:0005730nucleolusPola1ISSUniProtKB:P09884RatRGD:1600115
Cellular ComponentGO:0005730nucleolusQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Cellular ComponentGO:0005654nucleoplasmPOLA1IDAHumanPMID:7045121
Cellular ComponentGO:0005654nucleoplasmPOLA1EXPHumanPMID:11473323
Cellular ComponentGO:0005654nucleoplasmPOLA1EXPHumanPMID:9822671
Cellular ComponentGO:0005654nucleoplasmPOLA1EXPHumanPMID:6693436
Cellular ComponentGO:0005654nucleoplasmPola1ISSUniProtKB:P09884RatRGD:1600115
Cellular ComponentGO:0005654nucleoplasmQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Cellular ComponentGO:0005634nucleusPOLA1IDAHumanPMID:4084590
Cellular ComponentGO:0005634nucleusPOLA1IDAHumanPMID:16762037
Cellular ComponentGO:0005634nucleusPola1IDAMouseMGI:MGI:1203906|PMID:9584195
Cellular ComponentGO:0005634nucleusPola1IMPRatRGD:1580616|PMID:10969999
Cellular ComponentGO:0005634nucleusPola1ISSUniProtKB:P09884RatRGD:1600115
Cellular ComponentGO:0005634nucleusQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Cellular ComponentGO:0005634nucleusY47D3A.29ISSUniProtKB:P09884WormWB:WBPaper00003297
Cellular ComponentGO:0005634nucleuspol1IDAPombePMID:16823372
Cellular ComponentGO:0005657replication forkPOL1IDAYeastSGD_REF:S000081149|PMID:15773893
Cellular ComponentGO:0005657replication forkpol1IGISGD:S000005046PombePMID:8423854
Biological ProcessGO:0008283cell proliferationPOLA1IDAHumanPMID:3359994
Biological ProcessGO:0008283cell proliferationPola1ISSUniProtKB:P09884RatRGD:1600115
Biological ProcessGO:0008283cell proliferationQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Biological ProcessGO:0006260DNA replicationPola1IDAMouseMGI:MGI:1203906|PMID:9584195
Biological ProcessGO:0006260DNA replicationPola1IMPMouseMGI:MGI:67849|PMID:8125989
Biological ProcessGO:0006260DNA replicationPola1IDAMouseMGI:MGI:64718|PMID:8106564
Biological ProcessGO:0006260DNA replicationPola1IMPRatRGD:1580606|PMID:8576284
Biological ProcessGO:0006260DNA replicationY47D3A.29ISSUniProtKB:P33609WormWB:WBPaper00003297
Biological ProcessGO:0006260DNA replicationpolA1ISSInterPro:IPR001098DictydictyBase_REF:10155
Biological ProcessGO:0006260DNA replicationPOL1IMPYeastSGD_REF:S000056892|PMID:2651896
Biological ProcessGO:0000076DNA replication checkpointpol1IMPPombePMID:8537450
Biological ProcessGO:0006270DNA replication initiationPOLA1IDAHumanPMID:2175912
Biological ProcessGO:0006270DNA replication initiationPola1ISSUniProtKB:P09884RatRGD:1600115
Biological ProcessGO:0006270DNA replication initiationQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Biological ProcessGO:0006270DNA replication initiationpolA1ISSUniProt:P09884DictydictyBase_REF:10155
Biological ProcessGO:0006270DNA replication initiationPOL1ICGO:0005658YeastSGD_REF:S000064605|PMID:3888995
Biological ProcessGO:0006270DNA replication initiationpol1IMPPombePMID:8537450
Biological ProcessGO:0006269DNA replication, synthesis of RNA primerpol1IGISGD:S000005046PombePMID:8537450
Biological ProcessGO:0000731DNA synthesis during DNA repairPOLA1IDAHumanPMID:3335506
Biological ProcessGO:0000731DNA synthesis during DNA repairPola1ISSUniProtKB:P09884RatRGD:1600115
Biological ProcessGO:0000731DNA synthesis during DNA repairQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Biological ProcessGO:0000731DNA synthesis during DNA repairpolA1ISSSGD:S000005046DictydictyBase_REF:10155
Biological ProcessGO:0000731DNA synthesis during DNA repairPOL1IMPYeastSGD_REF:S000056892|PMID:2651896
Biological ProcessGO:0000731DNA synthesis during DNA repairPOL1IMPYeastSGD_REF:S000056091|PMID:10025407
Biological ProcessGO:0006303double-strand break repair via nonhomologous end joiningPOLA1IMPHumanPMID:11470886
Biological ProcessGO:0006303double-strand break repair via nonhomologous end joiningPola1ISSUniProtKB:P09884RatRGD:1600115
Biological ProcessGO:0006303double-strand break repair via nonhomologous end joiningQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Biological ProcessGO:0009792embryonic development ending in birth or egg hatchingY47D3A.29IMPWB:WBRNAi00009341|WB:WBPhenotype:0000050WormWB:WBPaper00005654|PMID:12529635
Biological ProcessGO:0009792embryonic development ending in birth or egg hatchingY47D3A.29IMPWB:WBRNAi00009342|WB:WBPhenotype:0000050WormWB:WBPaper00005654|PMID:12529635
Biological ProcessGO:0009792embryonic development ending in birth or egg hatchingY47D3A.29IMPWB:WBRNAi00026719|WB:WBPhenotype:0000050WormWB:WBPaper00006395|PMID:14551910
Biological ProcessGO:0009792embryonic development ending in birth or egg hatchingY47D3A.29IMPWB:WBRNAi00026720|WB:WBPhenotype:0000050WormWB:WBPaper00006395|PMID:14551910
Biological ProcessGO:0009792embryonic development ending in birth or egg hatchingY47D3A.29IMPWB:WBRNAi00056755|WB:WBPhenotype:0000050WormWB:WBPaper00025054|PMID:15791247
Biological ProcessGO:0000734gene conversion at mating-type locus, DNA repair synthesispol1IMPPombePMID:8423854
Biological ProcessGO:0006273lagging strand elongationPOLA1IDAHumanPMID:2175912
Biological ProcessGO:0006273lagging strand elongationPOLA1IDAHumanPMID:7910375
Biological ProcessGO:0006273lagging strand elongationPola1ISSUniProtKB:P09884RatRGD:1600115
Biological ProcessGO:0006273lagging strand elongationQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Biological ProcessGO:0006273lagging strand elongationpolA1ISSUniProt:P09884DictydictyBase_REF:10155
Biological ProcessGO:0006273lagging strand elongationPOL1ICGO:0005658YeastSGD_REF:S000064605|PMID:3888995
Biological ProcessGO:0006272leading strand elongationPOLA1IDAHumanPMID:2175912
Biological ProcessGO:0006272leading strand elongationPOLA1IDAHumanPMID:7910375
Biological ProcessGO:0006272leading strand elongationPola1ISSUniProtKB:P09884RatRGD:1600115
Biological ProcessGO:0006272leading strand elongationQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Biological ProcessGO:0006272leading strand elongationpolA1ISSUniProt:P09884DictydictyBase_REF:10155
Biological ProcessGO:0006279premeiotic DNA synthesisPOL1IMPYeastSGD_REF:S000056892|PMID:2651896
Biological ProcessGO:0035046pronuclear migrationY47D3A.29IMPWB:WBRNAi00056755|WB:WBPhenotype:0001152WormWB:WBPaper00025054|PMID:15791247
Biological ProcessGO:0006278RNA-dependent DNA replicationPOL1IDAYeastSGD_REF:S000122326|PMID:17429354
Biological ProcessGO:0000084S phase of mitotic cell cyclePOLA1IDAHumanPMID:16762037
Biological ProcessGO:0000084S phase of mitotic cell cyclePola1ISSUniProtKB:P09884RatRGD:1600115
Biological ProcessGO:0000084S phase of mitotic cell cycleQ59J86ISSUniProtKB:P09884ChickenUniProtKB:Q59J86
Biological ProcessGO:0000723telomere maintenancepol1IMPPombePMID:12697806

Gene Ontology Evidence Code Abbreviations:

  IC Inferred by curator
  IDA Inferred from direct assay
  IEA Inferred from electronic annotation
  IEP Inferred from expression pattern
  IGC Inferred from genomic context
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  ISA Inferred from sequence alignment
  ISM Inferred from sequence model
  ISO Inferred from sequence orthology
  ISS Inferred from sequence or structural similarity
  NAS Non-traceable Author Statement
  ND No biological data available
  RCA Reviewed computational analysis
  TAS Traceable author statement
  NR Not recorded (appears in some legacy annotations)