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<text text-anchor="middle" x="1514" y="-221.667" style="font-family:Arial;font-size:10px;">recombination</text>
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<!-- GO:0000712 -->
<g id="node23" class="node"><title>GO:0000712</title>
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<!-- GO:0007131&#45;&gt;GO:0000712 -->
<g id="edge377" class="edge"><title>GO:0007131&#45;&gt;GO:0000712</title>
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<!-- GO:0006295 -->
<g id="node10" class="node"><title>GO:0006295</title>
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<!-- GO:0007534 -->
<g id="node11" class="node"><title>GO:0007534</title>
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<text text-anchor="middle" x="3444" y="-349.667" style="font-family:Arial;font-size:10px;">gene conversion</text>
<text text-anchor="middle" x="3444" y="-337.667" style="font-family:Arial;font-size:10px;">at mating&#45;type</text>
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<!-- GO:0007534&#45;&gt;GO:0000735 -->
<g id="edge73" class="edge"><title>GO:0007534&#45;&gt;GO:0000735</title>
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<!-- GO:0004520 -->
<g id="node12" class="node"><title>GO:0004520</title>
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<polygon style="fill:none;stroke:black;" points="625,-560 625,-590 733,-590 733,-560 625,-560"/>
<text text-anchor="middle" x="679" y="-579.667" style="font-family:Arial;font-size:10px;">endodeoxyribonuclease</text>
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<!-- GO:0000014 -->
<g id="node36" class="node"><title>GO:0000014</title>
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<text text-anchor="middle" x="679" y="-429.667" style="font-family:Arial;font-size:10px;">Dicty: ISS_only</text>
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<!-- GO:0004520&#45;&gt;GO:0000014 -->
<g id="edge427" class="edge"><title>GO:0004520&#45;&gt;GO:0000014</title>
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</g>
<!-- GO:0006289 -->
<g id="node13" class="node"><title>GO:0006289</title>
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<polygon style="fill:none;stroke:black;" points="3822,-452 3822,-482 3912,-482 3912,-452 3822,-452"/>
<text text-anchor="middle" x="3867" y="-471.667" style="font-family:Arial;font-size:10px;">nucleotide&#45;excision</text>
<text text-anchor="middle" x="3867" y="-459.667" style="font-family:Arial;font-size:10px;">repair</text>
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<text text-anchor="middle" x="3867" y="-441.667" style="font-family:Arial;font-size:10px;">Mouse: ISS_only</text>
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<text text-anchor="middle" x="3867" y="-425.667" style="font-family:Arial;font-size:10px;">Pombe</text>
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<!-- GO:0000718 -->
<g id="node17" class="node"><title>GO:0000718</title>
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<text text-anchor="middle" x="3904" y="-349.667" style="font-family:Arial;font-size:10px;">nucleotide&#45;excision</text>
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<text text-anchor="middle" x="3904" y="-325.667" style="font-family:Arial;font-size:10px;">damage removal</text>
<text text-anchor="middle" x="3904" y="-313.667" style="font-family:Arial;font-size:10px;">Human: ISS_only</text>
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<!-- GO:0006289&#45;&gt;GO:0000718 -->
<g id="edge271" class="edge"><title>GO:0006289&#45;&gt;GO:0000718</title>
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<!-- GO:0033683 -->
<g id="node90" class="node"><title>GO:0033683</title>
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<text text-anchor="middle" x="3740" y="-343.667" style="font-family:Arial;font-size:10px;">nucleotide&#45;excision</text>
<text text-anchor="middle" x="3740" y="-331.667" style="font-family:Arial;font-size:10px;">repair, DNA</text>
<text text-anchor="middle" x="3740" y="-319.667" style="font-family:Arial;font-size:10px;">incision</text>
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<!-- GO:0006289&#45;&gt;GO:0033683 -->
<g id="edge181" class="edge"><title>GO:0006289&#45;&gt;GO:0033683</title>
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<!-- GO:0009792 -->
<g id="node14" class="node"><title>GO:0009792</title>
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<text text-anchor="middle" x="4655" y="-777.667" style="font-family:Arial;font-size:10px;">embryonic development</text>
<text text-anchor="middle" x="4655" y="-765.667" style="font-family:Arial;font-size:10px;">ending in birth</text>
<text text-anchor="middle" x="4655" y="-753.667" style="font-family:Arial;font-size:10px;">or egg hatching</text>
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<!-- GO:0006298 -->
<g id="node15" class="node"><title>GO:0006298</title>
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<text text-anchor="middle" x="3857" y="-227.667" style="font-family:Arial;font-size:10px;">mismatch repair</text>
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<!-- GO:0000710 -->
<g id="node27" class="node"><title>GO:0000710</title>
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<text text-anchor="middle" x="2787" y="-119.667" style="font-family:Arial;font-size:10px;">meiotic mismatch</text>
<text text-anchor="middle" x="2787" y="-107.667" style="font-family:Arial;font-size:10px;">repair</text>
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<!-- GO:0006298&#45;&gt;GO:0000710 -->
<g id="edge383" class="edge"><title>GO:0006298&#45;&gt;GO:0000710</title>
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<!-- GO:0006312 -->
<g id="node16" class="node"><title>GO:0006312</title>
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<text text-anchor="middle" x="3444" y="-447.667" style="font-family:Arial;font-size:10px;">mitotic recombination</text>
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<!-- GO:0006312&#45;&gt;GO:0007534 -->
<g id="edge75" class="edge"><title>GO:0006312&#45;&gt;GO:0007534</title>
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<!-- GO:0003677 -->
<g id="node18" class="node"><title>GO:0003677</title>
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<text text-anchor="middle" x="469" y="-845.667" style="font-family:Arial;font-size:10px;">DNA binding</text>
<text text-anchor="middle" x="469" y="-833.667" style="font-family:Arial;font-size:10px;">Pombe: ISS_only</text>
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<!-- GO:0003684 -->
<g id="node29" class="node"><title>GO:0003684</title>
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<text text-anchor="middle" x="406" y="-771.667" style="font-family:Arial;font-size:10px;">damaged DNA</text>
<text text-anchor="middle" x="406" y="-759.667" style="font-family:Arial;font-size:10px;">binding</text>
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<!-- GO:0003677&#45;&gt;GO:0003684 -->
<g id="edge391" class="edge"><title>GO:0003677&#45;&gt;GO:0003684</title>
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<!-- GO:0043566 -->
<g id="node41" class="node"><title>GO:0043566</title>
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<text text-anchor="middle" x="515" y="-765.667" style="font-family:Arial;font-size:10px;">structure&#45;specific</text>
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<!-- GO:0003677&#45;&gt;GO:0043566 -->
<g id="edge5" class="edge"><title>GO:0003677&#45;&gt;GO:0043566</title>
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<!-- GO:0045132 -->
<g id="node19" class="node"><title>GO:0045132</title>
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<text text-anchor="middle" x="1797" y="-343.667" style="font-family:Arial;font-size:10px;">meiotic chromosome</text>
<text text-anchor="middle" x="1797" y="-331.667" style="font-family:Arial;font-size:10px;">segregation</text>
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<!-- GO:0016321 -->
<g id="node38" class="node"><title>GO:0016321</title>
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<text text-anchor="middle" x="1915" y="-233.667" style="font-family:Arial;font-size:10px;">female meiosis</text>
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<!-- GO:0045132&#45;&gt;GO:0016321 -->
<g id="edge581" class="edge"><title>GO:0045132&#45;&gt;GO:0016321</title>
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<!-- GO:0051307 -->
<g id="node135" class="node"><title>GO:0051307</title>
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<text text-anchor="middle" x="1637" y="-227.667" style="font-family:Arial;font-size:10px;">meiotic chromosome</text>
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<!-- GO:0045132&#45;&gt;GO:0051307 -->
<g id="edge375" class="edge"><title>GO:0045132&#45;&gt;GO:0051307</title>
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<!-- GO:0000784 -->
<g id="node20" class="node"><title>GO:0000784</title>
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<text text-anchor="middle" x="1030" y="-35.6667" style="font-family:Arial;font-size:10px;">nuclear chromosome,</text>
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<!-- GO:0000109 -->
<g id="node21" class="node"><title>GO:0000109</title>
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<text text-anchor="middle" x="1394" y="-251.667" style="font-family:Arial;font-size:10px;">nucleotide&#45;excision</text>
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<text text-anchor="middle" x="1394" y="-205.667" style="font-family:Arial;font-size:10px;">Mouse: ISS_only</text>
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<text text-anchor="middle" x="1394" y="-189.667" style="font-family:Arial;font-size:10px;">Pombe: ISS_only</text>
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<!-- GO:0000110 -->
<g id="node31" class="node"><title>GO:0000110</title>
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<polygon style="fill:none;stroke:black;" points="1349,-104 1349,-146 1439,-146 1439,-104 1349,-104"/>
<text text-anchor="middle" x="1394" y="-135.667" style="font-family:Arial;font-size:10px;">nucleotide&#45;excision</text>
<text text-anchor="middle" x="1394" y="-123.667" style="font-family:Arial;font-size:10px;">repair factor</text>
<text text-anchor="middle" x="1394" y="-111.667" style="font-family:Arial;font-size:10px;">1 complex</text>
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<!-- GO:0000109&#45;&gt;GO:0000110 -->
<g id="edge393" class="edge"><title>GO:0000109&#45;&gt;GO:0000110</title>
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<!-- GO:0000736 -->
<g id="node22" class="node"><title>GO:0000736</title>
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<text text-anchor="middle" x="4069" y="-257.667" style="font-family:Arial;font-size:10px;">double&#45;strand</text>
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<!-- GO:0005634 -->
<g id="node24" class="node"><title>GO:0005634</title>
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<!-- GO:0044428 -->
<g id="node127" class="node"><title>GO:0044428</title>
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<text text-anchor="middle" x="1199" y="-330.667" style="font-family:Arial;font-size:10px;">nuclear part</text>
</g>
<!-- GO:0005634&#45;&gt;GO:0044428 -->
<g id="edge331" class="edge"><title>GO:0005634&#45;&gt;GO:0044428</title>
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</g>
<!-- GO:0008022 -->
<g id="node25" class="node"><title>GO:0008022</title>
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<text text-anchor="middle" x="51" y="-851.667" style="font-family:Arial;font-size:10px;">protein C&#45;terminus</text>
<text text-anchor="middle" x="51" y="-839.667" style="font-family:Arial;font-size:10px;">binding</text>
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<!-- GO:0005515 -->
<g id="node26" class="node"><title>GO:0005515</title>
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<text text-anchor="middle" x="232" y="-907.667" style="font-family:Arial;font-size:10px;">protein binding</text>
<text text-anchor="middle" x="232" y="-895.667" style="font-family:Arial;font-size:10px;">Fly</text>
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<!-- GO:0005515&#45;&gt;GO:0008022 -->
<g id="edge379" class="edge"><title>GO:0005515&#45;&gt;GO:0008022</title>
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<!-- GO:0047485 -->
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<text text-anchor="middle" x="171" y="-851.667" style="font-family:Arial;font-size:10px;">protein N&#45;terminus</text>
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<!-- GO:0005515&#45;&gt;GO:0047485 -->
<g id="edge389" class="edge"><title>GO:0005515&#45;&gt;GO:0047485</title>
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<!-- GO:0046983 -->
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<polygon style="fill:none;stroke:black;" points="248,-826 248,-856 338,-856 338,-826 248,-826"/>
<text text-anchor="middle" x="293" y="-845.667" style="font-family:Arial;font-size:10px;">protein dimerization</text>
<text text-anchor="middle" x="293" y="-833.667" style="font-family:Arial;font-size:10px;">activity</text>
</g>
<!-- GO:0005515&#45;&gt;GO:0046983 -->
<g id="edge423" class="edge"><title>GO:0005515&#45;&gt;GO:0046983</title>
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<polygon style="fill:gray;stroke:gray;" points="251.596,-878.454 247,-888 256.546,-883.404 251.596,-878.454"/>
</g>
<!-- GO:0043234 -->
<g id="node30" class="node"><title>GO:0043234</title>
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<text text-anchor="middle" x="1403" y="-337.667" style="font-family:Arial;font-size:10px;">protein complex</text>
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<!-- GO:0043234&#45;&gt;GO:0000109 -->
<g id="edge347" class="edge"><title>GO:0043234&#45;&gt;GO:0000109</title>
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<!-- GO:0005654 -->
<g id="node32" class="node"><title>GO:0005654</title>
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<text text-anchor="middle" x="1244" y="-113.667" style="font-family:Arial;font-size:10px;">nucleoplasm</text>
<text text-anchor="middle" x="1244" y="-101.667" style="font-family:Arial;font-size:10px;">Human: ISS_only</text>
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<!-- GO:0000724 -->
<g id="node33" class="node"><title>GO:0000724</title>
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<text text-anchor="middle" x="4059" y="-355.667" style="font-family:Arial;font-size:10px;">double&#45;strand</text>
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<text text-anchor="middle" x="4059" y="-331.667" style="font-family:Arial;font-size:10px;">via homologous</text>
<text text-anchor="middle" x="4059" y="-319.667" style="font-family:Arial;font-size:10px;">recombination</text>
<text text-anchor="middle" x="4059" y="-307.667" style="font-family:Arial;font-size:10px;">Human</text>
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<!-- GO:0046982 -->
<g id="node34" class="node"><title>GO:0046982</title>
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<polygon style="fill:none;stroke:black;" points="219,-762 219,-792 337,-792 337,-762 219,-762"/>
<text text-anchor="middle" x="278" y="-781.667" style="font-family:Arial;font-size:10px;">protein heterodimerization</text>
<text text-anchor="middle" x="278" y="-769.667" style="font-family:Arial;font-size:10px;">activity</text>
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<text text-anchor="middle" x="278" y="-735.667" style="font-family:Arial;font-size:10px;">Fly</text>
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<!-- GO:0006296 -->
<g id="node35" class="node"><title>GO:0006296</title>
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<text text-anchor="middle" x="3740" y="-263.667" style="font-family:Arial;font-size:10px;">nucleotide&#45;excision</text>
<text text-anchor="middle" x="3740" y="-251.667" style="font-family:Arial;font-size:10px;">repair, DNA</text>
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<text text-anchor="middle" x="3740" y="-193.667" style="font-family:Arial;font-size:10px;">Dicty: ISS_only</text>
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</g>
<!-- GO:0032205 -->
<g id="node37" class="node"><title>GO:0032205</title>
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<text text-anchor="middle" x="2472" y="-349.667" style="font-family:Arial;font-size:10px;">negative regulation</text>
<text text-anchor="middle" x="2472" y="-337.667" style="font-family:Arial;font-size:10px;">of telomere</text>
<text text-anchor="middle" x="2472" y="-325.667" style="font-family:Arial;font-size:10px;">maintenance</text>
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</g>
<!-- GO:0006311 -->
<g id="node39" class="node"><title>GO:0006311</title>
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<text text-anchor="middle" x="1788" y="-221.667" style="font-family:Arial;font-size:10px;">conversion</text>
<text text-anchor="middle" x="1788" y="-209.667" style="font-family:Arial;font-size:10px;">Pombe</text>
</g>
<!-- GO:0006281 -->
<g id="node40" class="node"><title>GO:0006281</title>
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<text text-anchor="middle" x="4059" y="-563.667" style="font-family:Arial;font-size:10px;">DNA repair</text>
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</g>
<!-- GO:0006281&#45;&gt;GO:0006289 -->
<g id="edge183" class="edge"><title>GO:0006281&#45;&gt;GO:0006289</title>
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</g>
<!-- GO:0006281&#45;&gt;GO:0006298 -->
<g id="edge229" class="edge"><title>GO:0006281&#45;&gt;GO:0006298</title>
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<!-- GO:0000726 -->
<g id="node133" class="node"><title>GO:0000726</title>
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<text text-anchor="middle" x="4275" y="-447.667" style="font-family:Arial;font-size:10px;">non&#45;recombinational</text>
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<!-- GO:0006281&#45;&gt;GO:0000726 -->
<g id="edge361" class="edge"><title>GO:0006281&#45;&gt;GO:0000726</title>
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</g>
<!-- GO:0006302 -->
<g id="node134" class="node"><title>GO:0006302</title>
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<text text-anchor="middle" x="4162" y="-447.667" style="font-family:Arial;font-size:10px;">double&#45;strand</text>
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</g>
<!-- GO:0006281&#45;&gt;GO:0006302 -->
<g id="edge365" class="edge"><title>GO:0006281&#45;&gt;GO:0006302</title>
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</g>
<!-- GO:0000725 -->
<g id="node141" class="node"><title>GO:0000725</title>
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<text text-anchor="middle" x="4059" y="-447.667" style="font-family:Arial;font-size:10px;">recombinational</text>
<text text-anchor="middle" x="4059" y="-435.667" style="font-family:Arial;font-size:10px;">repair</text>
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<!-- GO:0006281&#45;&gt;GO:0000725 -->
<g id="edge415" class="edge"><title>GO:0006281&#45;&gt;GO:0000725</title>
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</g>
<!-- GO:0043566&#45;&gt;GO:0003697 -->
<g id="edge3" class="edge"><title>GO:0043566&#45;&gt;GO:0003697</title>
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</g>
<!-- GO:0003676 -->
<g id="node42" class="node"><title>GO:0003676</title>
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<text text-anchor="middle" x="469" y="-907.667" style="font-family:Arial;font-size:10px;">nucleic acid</text>
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</g>
<!-- GO:0003676&#45;&gt;GO:0003677 -->
<g id="edge7" class="edge"><title>GO:0003676&#45;&gt;GO:0003677</title>
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<!-- GO:0005488&#45;&gt;GO:0005515 -->
<g id="edge381" class="edge"><title>GO:0005488&#45;&gt;GO:0005515</title>
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<!-- GO:0005488&#45;&gt;GO:0003676 -->
<g id="edge9" class="edge"><title>GO:0005488&#45;&gt;GO:0003676</title>
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</g>
<!-- GO:0000737 -->
<g id="node44" class="node"><title>GO:0000737</title>
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<text text-anchor="middle" x="3731" y="-447.667" style="font-family:Arial;font-size:10px;">DNA catabolic</text>
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</g>
<!-- GO:0000737&#45;&gt;GO:0000735 -->
<g id="edge13" class="edge"><title>GO:0000737&#45;&gt;GO:0000735</title>
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<!-- GO:0000737&#45;&gt;GO:0000736 -->
<g id="edge355" class="edge"><title>GO:0000737&#45;&gt;GO:0000736</title>
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<!-- GO:0000737&#45;&gt;GO:0033683 -->
<g id="edge179" class="edge"><title>GO:0000737&#45;&gt;GO:0033683</title>
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<!-- GO:0006308 -->
<g id="node45" class="node"><title>GO:0006308</title>
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<text text-anchor="middle" x="3948" y="-563.667" style="font-family:Arial;font-size:10px;">DNA catabolic</text>
<text text-anchor="middle" x="3948" y="-551.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0006308&#45;&gt;GO:0000718 -->
<g id="edge269" class="edge"><title>GO:0006308&#45;&gt;GO:0000718</title>
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<!-- GO:0006308&#45;&gt;GO:0000737 -->
<g id="edge15" class="edge"><title>GO:0006308&#45;&gt;GO:0000737</title>
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<!-- GO:0006259 -->
<g id="node46" class="node"><title>GO:0006259</title>
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<text text-anchor="middle" x="3449" y="-667.667" style="font-family:Arial;font-size:10px;">DNA metabolic</text>
<text text-anchor="middle" x="3449" y="-655.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0006259&#45;&gt;GO:0006281 -->
<g id="edge185" class="edge"><title>GO:0006259&#45;&gt;GO:0006281</title>
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<!-- GO:0006259&#45;&gt;GO:0006308 -->
<g id="edge17" class="edge"><title>GO:0006259&#45;&gt;GO:0006308</title>
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<!-- GO:0006310 -->
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<text text-anchor="middle" x="3449" y="-556.667" style="font-family:Arial;font-size:10px;">DNA recombination</text>
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<!-- GO:0006259&#45;&gt;GO:0006310 -->
<g id="edge79" class="edge"><title>GO:0006259&#45;&gt;GO:0006310</title>
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<!-- GO:0007533 -->
<g id="node62" class="node"><title>GO:0007533</title>
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<text text-anchor="middle" x="3303" y="-563.667" style="font-family:Arial;font-size:10px;">mating type</text>
<text text-anchor="middle" x="3303" y="-551.667" style="font-family:Arial;font-size:10px;">switching</text>
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<!-- GO:0006259&#45;&gt;GO:0007533 -->
<g id="edge83" class="edge"><title>GO:0006259&#45;&gt;GO:0007533</title>
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<!-- GO:0045005 -->
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<text text-anchor="middle" x="3571" y="-349.667" style="font-family:Arial;font-size:10px;">maintenance</text>
<text text-anchor="middle" x="3571" y="-337.667" style="font-family:Arial;font-size:10px;">of fidelity</text>
<text text-anchor="middle" x="3571" y="-325.667" style="font-family:Arial;font-size:10px;">during DNA&#45;dependent</text>
<text text-anchor="middle" x="3571" y="-313.667" style="font-family:Arial;font-size:10px;">DNA replication</text>
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<!-- GO:0006259&#45;&gt;GO:0045005 -->
<g id="edge233" class="edge"><title>GO:0006259&#45;&gt;GO:0045005</title>
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<!-- GO:0006260 -->
<g id="node105" class="node"><title>GO:0006260</title>
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<text text-anchor="middle" x="3603" y="-556.667" style="font-family:Arial;font-size:10px;">DNA replication</text>
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<!-- GO:0006259&#45;&gt;GO:0006260 -->
<g id="edge239" class="edge"><title>GO:0006259&#45;&gt;GO:0006260</title>
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<!-- GO:0051052 -->
<g id="node160" class="node"><title>GO:0051052</title>
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<polygon style="fill:none;stroke:black;" points="3073,-538 3073,-580 3145,-580 3145,-538 3073,-538"/>
<text text-anchor="middle" x="3109" y="-569.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="3109" y="-557.667" style="font-family:Arial;font-size:10px;">DNA metabolic</text>
<text text-anchor="middle" x="3109" y="-545.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0006259&#45;&gt;GO:0051052 -->
<g id="edge519" class="edge"><title>GO:0006259&#45;&gt;GO:0051052</title>
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<!-- GO:0000723 -->
<g id="node165" class="node"><title>GO:0000723</title>
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<polygon style="fill:none;stroke:black;" points="2551,-551 2551,-567 2653,-567 2653,-551 2551,-551"/>
<text text-anchor="middle" x="2602" y="-556.667" style="font-family:Arial;font-size:10px;">telomere maintenance</text>
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<!-- GO:0006259&#45;&gt;GO:0000723 -->
<g id="edge523" class="edge"><title>GO:0006259&#45;&gt;GO:0000723</title>
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<!-- GO:0051053 -->
<g id="node169" class="node"><title>GO:0051053</title>
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<polygon style="fill:none;stroke:black;" points="3066,-422 3066,-464 3152,-464 3152,-422 3066,-422"/>
<text text-anchor="middle" x="3109" y="-453.667" style="font-family:Arial;font-size:10px;">negative regulation</text>
<text text-anchor="middle" x="3109" y="-441.667" style="font-family:Arial;font-size:10px;">of DNA metabolic</text>
<text text-anchor="middle" x="3109" y="-429.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0006259&#45;&gt;GO:0051053 -->
<g id="edge575" class="edge"><title>GO:0006259&#45;&gt;GO:0051053</title>
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<!-- GO:0006139 -->
<g id="node47" class="node"><title>GO:0006139</title>
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<polygon style="fill:none;stroke:black;" points="3027,-728 3027,-794 3113,-794 3113,-728 3027,-728"/>
<text text-anchor="middle" x="3070" y="-783.667" style="font-family:Arial;font-size:10px;">nucleobase,</text>
<text text-anchor="middle" x="3070" y="-771.667" style="font-family:Arial;font-size:10px;">nucleoside,</text>
<text text-anchor="middle" x="3070" y="-759.667" style="font-family:Arial;font-size:10px;">nucleotide and</text>
<text text-anchor="middle" x="3070" y="-747.667" style="font-family:Arial;font-size:10px;">nucleic acid</text>
<text text-anchor="middle" x="3070" y="-735.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0006139&#45;&gt;GO:0006259 -->
<g id="edge19" class="edge"><title>GO:0006139&#45;&gt;GO:0006259</title>
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<!-- GO:0019219 -->
<g id="node161" class="node"><title>GO:0019219</title>
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<polygon style="fill:none;stroke:black;" points="2951,-624 2951,-702 3037,-702 3037,-624 2951,-624"/>
<text text-anchor="middle" x="2994" y="-691.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="2994" y="-679.667" style="font-family:Arial;font-size:10px;">nucleobase,</text>
<text text-anchor="middle" x="2994" y="-667.667" style="font-family:Arial;font-size:10px;">nucleoside,</text>
<text text-anchor="middle" x="2994" y="-655.667" style="font-family:Arial;font-size:10px;">nucleotide and</text>
<text text-anchor="middle" x="2994" y="-643.667" style="font-family:Arial;font-size:10px;">nucleic acid</text>
<text text-anchor="middle" x="2994" y="-631.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0006139&#45;&gt;GO:0019219 -->
<g id="edge511" class="edge"><title>GO:0006139&#45;&gt;GO:0019219</title>
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<!-- GO:0045934 -->
<g id="node172" class="node"><title>GO:0045934</title>
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<polygon style="fill:none;stroke:black;" points="2952,-520 2952,-598 3038,-598 3038,-520 2952,-520"/>
<text text-anchor="middle" x="2995" y="-587.667" style="font-family:Arial;font-size:10px;">negative regulation</text>
<text text-anchor="middle" x="2995" y="-575.667" style="font-family:Arial;font-size:10px;">of nucleobase,</text>
<text text-anchor="middle" x="2995" y="-563.667" style="font-family:Arial;font-size:10px;">nucleoside,</text>
<text text-anchor="middle" x="2995" y="-551.667" style="font-family:Arial;font-size:10px;">nucleotide and</text>
<text text-anchor="middle" x="2995" y="-539.667" style="font-family:Arial;font-size:10px;">nucleic acid</text>
<text text-anchor="middle" x="2995" y="-527.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0006139&#45;&gt;GO:0045934 -->
<g id="edge571" class="edge"><title>GO:0006139&#45;&gt;GO:0045934</title>
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<!-- GO:0044237 -->
<g id="node48" class="node"><title>GO:0044237</title>
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<text text-anchor="middle" x="3039" y="-907.667" style="font-family:Arial;font-size:10px;">cellular metabolic</text>
<text text-anchor="middle" x="3039" y="-895.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0044237&#45;&gt;GO:0006139 -->
<g id="edge21" class="edge"><title>GO:0044237&#45;&gt;GO:0006139</title>
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<!-- GO:0044260 -->
<g id="node55" class="node"><title>GO:0044260</title>
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<text text-anchor="middle" x="3903" y="-845.667" style="font-family:Arial;font-size:10px;">cellular macromolecule</text>
<text text-anchor="middle" x="3903" y="-833.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0044237&#45;&gt;GO:0044260 -->
<g id="edge47" class="edge"><title>GO:0044237&#45;&gt;GO:0044260</title>
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<!-- GO:0044248 -->
<g id="node60" class="node"><title>GO:0044248</title>
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<text text-anchor="middle" x="4161" y="-845.667" style="font-family:Arial;font-size:10px;">cellular catabolic</text>
<text text-anchor="middle" x="4161" y="-833.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0044237&#45;&gt;GO:0044248 -->
<g id="edge69" class="edge"><title>GO:0044237&#45;&gt;GO:0044248</title>
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<!-- GO:0044249 -->
<g id="node110" class="node"><title>GO:0044249</title>
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<text text-anchor="middle" x="3588" y="-845.667" style="font-family:Arial;font-size:10px;">cellular biosynthetic</text>
<text text-anchor="middle" x="3588" y="-833.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0044237&#45;&gt;GO:0044249 -->
<g id="edge257" class="edge"><title>GO:0044237&#45;&gt;GO:0044249</title>
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<!-- GO:0031323 -->
<g id="node162" class="node"><title>GO:0031323</title>
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<text text-anchor="middle" x="2914" y="-771.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="2914" y="-759.667" style="font-family:Arial;font-size:10px;">cellular metabolic</text>
<text text-anchor="middle" x="2914" y="-747.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0044237&#45;&gt;GO:0031323 -->
<g id="edge509" class="edge"><title>GO:0044237&#45;&gt;GO:0031323</title>
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<!-- GO:0031324 -->
<g id="node173" class="node"><title>GO:0031324</title>
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<text text-anchor="middle" x="2874" y="-673.667" style="font-family:Arial;font-size:10px;">negative regulation</text>
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<text text-anchor="middle" x="2874" y="-649.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0044237&#45;&gt;GO:0031324 -->
<g id="edge569" class="edge"><title>GO:0044237&#45;&gt;GO:0031324</title>
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<!-- GO:0008152&#45;&gt;GO:0044237 -->
<g id="edge23" class="edge"><title>GO:0008152&#45;&gt;GO:0044237</title>
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<!-- GO:0044238 -->
<g id="node51" class="node"><title>GO:0044238</title>
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<text text-anchor="middle" x="3156" y="-907.667" style="font-family:Arial;font-size:10px;">primary metabolic</text>
<text text-anchor="middle" x="3156" y="-895.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0008152&#45;&gt;GO:0044238 -->
<g id="edge33" class="edge"><title>GO:0008152&#45;&gt;GO:0044238</title>
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<!-- GO:0043170 -->
<g id="node54" class="node"><title>GO:0043170</title>
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<text text-anchor="middle" x="3780" y="-907.667" style="font-family:Arial;font-size:10px;">macromolecule</text>
<text text-anchor="middle" x="3780" y="-895.667" style="font-family:Arial;font-size:10px;">metabolic process</text>
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<!-- GO:0008152&#45;&gt;GO:0043170 -->
<g id="edge41" class="edge"><title>GO:0008152&#45;&gt;GO:0043170</title>
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<!-- GO:0009987&#45;&gt;GO:0048468 -->
<g id="edge105" class="edge"><title>GO:0009987&#45;&gt;GO:0048468</title>
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<!-- GO:0009987&#45;&gt;GO:0048869 -->
<g id="edge111" class="edge"><title>GO:0009987&#45;&gt;GO:0048869</title>
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<!-- GO:0009987&#45;&gt;GO:0048610 -->
<g id="edge119" class="edge"><title>GO:0009987&#45;&gt;GO:0048610</title>
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<!-- GO:0009987&#45;&gt;GO:0051301 -->
<g id="edge129" class="edge"><title>GO:0009987&#45;&gt;GO:0051301</title>
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<g id="edge151" class="edge"><title>GO:0009987&#45;&gt;GO:0022402</title>
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<!-- GO:0009987&#45;&gt;GO:0007049 -->
<g id="edge155" class="edge"><title>GO:0009987&#45;&gt;GO:0007049</title>
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<!-- GO:0009987&#45;&gt;GO:0051716 -->
<g id="edge197" class="edge"><title>GO:0009987&#45;&gt;GO:0051716</title>
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<!-- GO:0009987&#45;&gt;GO:0007059 -->
<g id="edge275" class="edge"><title>GO:0009987&#45;&gt;GO:0007059</title>
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<!-- GO:0009987&#45;&gt;GO:0050794 -->
<g id="edge445" class="edge"><title>GO:0009987&#45;&gt;GO:0050794</title>
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<!-- GO:0009987&#45;&gt;GO:0016043 -->
<g id="edge449" class="edge"><title>GO:0009987&#45;&gt;GO:0016043</title>
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<g id="edge467" class="edge"><title>GO:0009987&#45;&gt;GO:0048523</title>
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<g id="edge31" class="edge"><title>GO:0044238&#45;&gt;GO:0006139</title>
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<g id="edge35" class="edge"><title>GO:0034960&#45;&gt;GO:0006259</title>
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<g id="edge261" class="edge"><title>GO:0034960&#45;&gt;GO:0034961</title>
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<g id="edge39" class="edge"><title>GO:0043170&#45;&gt;GO:0043283</title>
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<g id="edge57" class="edge"><title>GO:0043170&#45;&gt;GO:0009057</title>
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<!-- GO:0043170&#45;&gt;GO:0009059 -->
<g id="edge251" class="edge"><title>GO:0043170&#45;&gt;GO:0009059</title>
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<text text-anchor="middle" x="3190" y="-759.667" style="font-family:Arial;font-size:10px;">macromolecule</text>
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<!-- GO:0043170&#45;&gt;GO:0060255 -->
<g id="edge517" class="edge"><title>GO:0043170&#45;&gt;GO:0060255</title>
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<g id="node170" class="node"><title>GO:0010605</title>
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<!-- GO:0043170&#45;&gt;GO:0010605 -->
<g id="edge555" class="edge"><title>GO:0043170&#45;&gt;GO:0010605</title>
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<g id="edge43" class="edge"><title>GO:0044260&#45;&gt;GO:0034960</title>
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<g id="node59" class="node"><title>GO:0044265</title>
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<!-- GO:0044260&#45;&gt;GO:0044265 -->
<g id="edge71" class="edge"><title>GO:0044260&#45;&gt;GO:0044265</title>
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<text text-anchor="middle" x="3747" y="-759.667" style="font-family:Arial;font-size:10px;">biosynthetic</text>
<text text-anchor="middle" x="3747" y="-747.667" style="font-family:Arial;font-size:10px;">process</text>
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<!-- GO:0044260&#45;&gt;GO:0034645 -->
<g id="edge259" class="edge"><title>GO:0044260&#45;&gt;GO:0034645</title>
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<g id="edge49" class="edge"><title>GO:0043285&#45;&gt;GO:0006308</title>
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<g id="edge51" class="edge"><title>GO:0009057&#45;&gt;GO:0043285</title>
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<g id="edge63" class="edge"><title>GO:0009057&#45;&gt;GO:0044265</title>
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<!-- GO:0009056&#45;&gt;GO:0009057 -->
<g id="edge53" class="edge"><title>GO:0009056&#45;&gt;GO:0009057</title>
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<g id="edge67" class="edge"><title>GO:0009056&#45;&gt;GO:0044248</title>
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<g id="edge61" class="edge"><title>GO:0044265&#45;&gt;GO:0006308</title>
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<g id="edge65" class="edge"><title>GO:0044248&#45;&gt;GO:0044265</title>
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<!-- GO:0006310&#45;&gt;GO:0007131 -->
<g id="edge147" class="edge"><title>GO:0006310&#45;&gt;GO:0007131</title>
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<g id="edge77" class="edge"><title>GO:0006310&#45;&gt;GO:0006312</title>
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<!-- GO:0006310&#45;&gt;GO:0006311 -->
<g id="edge587" class="edge"><title>GO:0006310&#45;&gt;GO:0006311</title>
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<!-- GO:0006310&#45;&gt;GO:0000725 -->
<g id="edge417" class="edge"><title>GO:0006310&#45;&gt;GO:0000725</title>
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<!-- GO:0007533&#45;&gt;GO:0007534 -->
<g id="edge81" class="edge"><title>GO:0007533&#45;&gt;GO:0007534</title>
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<!-- GO:0007531 -->
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<!-- GO:0007531&#45;&gt;GO:0007533 -->
<g id="edge85" class="edge"><title>GO:0007531&#45;&gt;GO:0007533</title>
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<!-- GO:0007530&#45;&gt;GO:0007531 -->
<g id="edge87" class="edge"><title>GO:0007530&#45;&gt;GO:0007531</title>
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<!-- GO:0003006&#45;&gt;GO:0007530 -->
<g id="edge89" class="edge"><title>GO:0003006&#45;&gt;GO:0007530</title>
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<g id="edge91" class="edge"><title>GO:0022414&#45;&gt;GO:0003006</title>
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<!-- GO:0022414&#45;&gt;GO:0048610 -->
<g id="edge121" class="edge"><title>GO:0022414&#45;&gt;GO:0048610</title>
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<!-- GO:0000003&#45;&gt;GO:0022414 -->
<g id="edge95" class="edge"><title>GO:0000003&#45;&gt;GO:0022414</title>
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<!-- GO:0000003&#45;&gt;GO:0032505 -->
<g id="edge125" class="edge"><title>GO:0000003&#45;&gt;GO:0032505</title>
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<!-- GO:0032502&#45;&gt;GO:0003006 -->
<g id="edge99" class="edge"><title>GO:0032502&#45;&gt;GO:0003006</title>
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<g id="edge113" class="edge"><title>GO:0032502&#45;&gt;GO:0048869</title>
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<g id="edge219" class="edge"><title>GO:0032502&#45;&gt;GO:0009790</title>
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<!-- GO:0032502&#45;&gt;GO:0007275 -->
<g id="edge227" class="edge"><title>GO:0032502&#45;&gt;GO:0007275</title>
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<g id="edge103" class="edge"><title>GO:0048468&#45;&gt;GO:0007531</title>
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<!-- GO:0030154&#45;&gt;GO:0048468 -->
<g id="edge107" class="edge"><title>GO:0030154&#45;&gt;GO:0048468</title>
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<g id="edge109" class="edge"><title>GO:0048869&#45;&gt;GO:0030154</title>
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<!-- GO:0022413&#45;&gt;GO:0007533 -->
<g id="edge115" class="edge"><title>GO:0022413&#45;&gt;GO:0007533</title>
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<g id="edge117" class="edge"><title>GO:0048610&#45;&gt;GO:0022413</title>
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<!-- GO:0032505&#45;&gt;GO:0022413 -->
<g id="edge123" class="edge"><title>GO:0032505&#45;&gt;GO:0022413</title>
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<g id="edge127" class="edge"><title>GO:0051301&#45;&gt;GO:0032505</title>
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<g id="edge135" class="edge"><title>GO:0009314&#45;&gt;GO:0009416</title>
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<g id="edge137" class="edge"><title>GO:0009628&#45;&gt;GO:0009314</title>
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<g id="edge145" class="edge"><title>GO:0050896&#45;&gt;GO:0006950</title>
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<g id="edge143" class="edge"><title>GO:0006950&#45;&gt;GO:0006974</title>
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<g id="edge193" class="edge"><title>GO:0006950&#45;&gt;GO:0033554</title>
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<g id="edge385" class="edge"><title>GO:0022402&#45;&gt;GO:0000710</title>
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<g id="edge589" class="edge"><title>GO:0022402&#45;&gt;GO:0006311</title>
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<g id="edge161" class="edge"><title>GO:0022402&#45;&gt;GO:0022403</title>
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<g id="edge175" class="edge"><title>GO:0007049&#45;&gt;GO:0051321</title>
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<g id="edge159" class="edge"><title>GO:0022403&#45;&gt;GO:0007127</title>
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<g id="edge165" class="edge"><title>GO:0022403&#45;&gt;GO:0007126</title>
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<g id="edge171" class="edge"><title>GO:0022403&#45;&gt;GO:0000279</title>
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<g id="edge203" class="edge"><title>GO:0004518&#45;&gt;GO:0004519</title>
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<polygon style="fill:gray;stroke:gray;" points="623.522,-743.398 628,-753 630.488,-742.701 623.522,-743.398"/>
</g>
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<g id="node99" class="node"><title>GO:0004536</title>
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<polygon style="fill:none;stroke:black;" points="690,-648 690,-678 778,-678 778,-648 690,-648"/>
<text text-anchor="middle" x="734" y="-667.667" style="font-family:Arial;font-size:10px;">deoxyribonuclease</text>
<text text-anchor="middle" x="734" y="-655.667" style="font-family:Arial;font-size:10px;">activity</text>
</g>
<!-- GO:0004518&#45;&gt;GO:0004536 -->
<g id="edge215" class="edge"><title>GO:0004518&#45;&gt;GO:0004536</title>
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<g id="node96" class="node"><title>GO:0016788</title>
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<text text-anchor="middle" x="614" y="-851.667" style="font-family:Arial;font-size:10px;">hydrolase activity,</text>
<text text-anchor="middle" x="614" y="-839.667" style="font-family:Arial;font-size:10px;">acting on ester</text>
<text text-anchor="middle" x="614" y="-827.667" style="font-family:Arial;font-size:10px;">bonds</text>
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<!-- GO:0016788&#45;&gt;GO:0004518 -->
<g id="edge205" class="edge"><title>GO:0016788&#45;&gt;GO:0004518</title>
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<g id="node97" class="node"><title>GO:0016787</title>
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<text text-anchor="middle" x="608" y="-900.667" style="font-family:Arial;font-size:10px;">hydrolase activity</text>
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<!-- GO:0016787&#45;&gt;GO:0016788 -->
<g id="edge207" class="edge"><title>GO:0016787&#45;&gt;GO:0016788</title>
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<!-- GO:0003824&#45;&gt;GO:0016787 -->
<g id="edge209" class="edge"><title>GO:0003824&#45;&gt;GO:0016787</title>
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<polygon style="fill:gray;stroke:gray;" points="588.863,-940.44 588,-951 595.26,-943.283 588.863,-940.44"/>
</g>
<!-- GO:0004536&#45;&gt;GO:0004520 -->
<g id="edge213" class="edge"><title>GO:0004536&#45;&gt;GO:0004520</title>
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<polygon style="fill:gray;stroke:gray;" points="716.084,-640.958 724,-648 722.203,-637.559 716.084,-640.958"/>
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<!-- GO:0009790&#45;&gt;GO:0009792 -->
<g id="edge217" class="edge"><title>GO:0009790&#45;&gt;GO:0009792</title>
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</g>
<!-- GO:0007275&#45;&gt;GO:0009790 -->
<g id="edge221" class="edge"><title>GO:0007275&#45;&gt;GO:0009790</title>
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<polygon style="fill:blue;stroke:blue;" points="4580.04,-880.084 4573,-888 4583.44,-886.203 4580.04,-880.084"/>
</g>
<!-- GO:0032501&#45;&gt;GO:0007275 -->
<g id="edge223" class="edge"><title>GO:0032501&#45;&gt;GO:0007275</title>
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<polygon style="fill:gray;stroke:gray;" points="4520.63,-933.738 4518,-944 4526.46,-937.621 4520.63,-933.738"/>
</g>
<!-- GO:0045005&#45;&gt;GO:0006298 -->
<g id="edge231" class="edge"><title>GO:0045005&#45;&gt;GO:0006298</title>
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<polygon style="fill:gray;stroke:gray;" points="3631.57,-305.774 3623,-312 3633.58,-312.479 3631.57,-305.774"/>
</g>
<!-- GO:0006261 -->
<g id="node104" class="node"><title>GO:0006261</title>
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<polygon style="fill:none;stroke:black;" points="3566,-428 3566,-458 3640,-458 3640,-428 3566,-428"/>
<text text-anchor="middle" x="3603" y="-447.667" style="font-family:Arial;font-size:10px;">DNA&#45;dependent</text>
<text text-anchor="middle" x="3603" y="-435.667" style="font-family:Arial;font-size:10px;">DNA replication</text>
</g>
<!-- GO:0006261&#45;&gt;GO:0045005 -->
<g id="edge235" class="edge"><title>GO:0006261&#45;&gt;GO:0045005</title>
<path style="fill:none;stroke:blue;" d="M3596,-418C3591,-401 3584,-378 3579,-360"/>
<polygon style="fill:blue;stroke:blue;" points="3592.77,-419.427 3599,-428 3599.48,-417.416 3592.77,-419.427"/>
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<!-- GO:0006260&#45;&gt;GO:0006261 -->
<g id="edge237" class="edge"><title>GO:0006260&#45;&gt;GO:0006261</title>
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<polygon style="fill:gray;stroke:gray;" points="3599.5,-541 3603,-551 3606.5,-541 3599.5,-541"/>
</g>
<!-- GO:0034961&#45;&gt;GO:0006260 -->
<g id="edge241" class="edge"><title>GO:0034961&#45;&gt;GO:0006260</title>
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<polygon style="fill:gray;stroke:gray;" points="3759.56,-640.203 3770,-642 3762.96,-634.084 3759.56,-640.203"/>
</g>
<!-- GO:0034645&#45;&gt;GO:0034961 -->
<g id="edge243" class="edge"><title>GO:0034645&#45;&gt;GO:0034961</title>
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<polygon style="fill:gray;stroke:gray;" points="3763.63,-729.738 3761,-740 3769.46,-733.621 3763.63,-729.738"/>
</g>
<!-- GO:0009059&#45;&gt;GO:0034645 -->
<g id="edge245" class="edge"><title>GO:0009059&#45;&gt;GO:0034645</title>
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<polygon style="fill:gray;stroke:gray;" points="3764.77,-811.427 3771,-820 3771.48,-809.416 3764.77,-811.427"/>
</g>
<!-- GO:0009059&#45;&gt;GO:0043284 -->
<g id="edge265" class="edge"><title>GO:0009059&#45;&gt;GO:0043284</title>
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</g>
<!-- GO:0009058&#45;&gt;GO:0009059 -->
<g id="edge247" class="edge"><title>GO:0009058&#45;&gt;GO:0009059</title>
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<polygon style="fill:gray;stroke:gray;" points="3625.57,-887.774 3617,-894 3627.58,-894.479 3625.57,-887.774"/>
</g>
<!-- GO:0009058&#45;&gt;GO:0044249 -->
<g id="edge255" class="edge"><title>GO:0009058&#45;&gt;GO:0044249</title>
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<polygon style="fill:gray;stroke:gray;" points="3584.5,-878 3588,-888 3591.5,-878 3584.5,-878"/>
</g>
<!-- GO:0044249&#45;&gt;GO:0034645 -->
<g id="edge253" class="edge"><title>GO:0044249&#45;&gt;GO:0034645</title>
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<polygon style="fill:gray;stroke:gray;" points="3625.72,-818.74 3618,-826 3628.56,-825.137 3625.72,-818.74"/>
</g>
<!-- GO:0043284&#45;&gt;GO:0034961 -->
<g id="edge263" class="edge"><title>GO:0043284&#45;&gt;GO:0034961</title>
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<polygon style="fill:gray;stroke:gray;" points="3971.56,-744.203 3982,-746 3974.96,-738.084 3971.56,-744.203"/>
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<!-- GO:0007059&#45;&gt;GO:0045132 -->
<g id="edge273" class="edge"><title>GO:0007059&#45;&gt;GO:0045132</title>
<path style="fill:none;stroke:gray;" d="M1782,-829C1797,-822 1814,-812 1826,-798 1880,-727 1861,-690 1872,-602 1883,-506 1875,-475 1834,-388 1828,-376 1820,-364 1813,-354"/>
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</g>
<!-- GO:0007059&#45;&gt;GO:0051304 -->
<g id="edge373" class="edge"><title>GO:0007059&#45;&gt;GO:0051304</title>
<path style="fill:none;stroke:blue;" d="M1721,-828C1692,-812 1642,-783 1618,-769"/>
<polygon style="fill:blue;stroke:blue;" points="1719.56,-831.203 1730,-833 1722.96,-825.084 1719.56,-831.203"/>
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<!-- GO:0000781 -->
<g id="node113" class="node"><title>GO:0000781</title>
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<polygon style="fill:none;stroke:black;" points="932,-94 932,-124 1008,-124 1008,-94 932,-94"/>
<text text-anchor="middle" x="970" y="-113.667" style="font-family:Arial;font-size:10px;">chromosome,</text>
<text text-anchor="middle" x="970" y="-101.667" style="font-family:Arial;font-size:10px;">telomeric region</text>
</g>
<!-- GO:0000781&#45;&gt;GO:0000784 -->
<g id="edge279" class="edge"><title>GO:0000781&#45;&gt;GO:0000784</title>
<path style="fill:none;stroke:gray;" d="M987,-86C995,-73 1006,-58 1015,-46"/>
<polygon style="fill:gray;stroke:gray;" points="984.2,-83.9 981,-94 989.8,-88.1 984.2,-83.9"/>
</g>
<!-- GO:0044427 -->
<g id="node114" class="node"><title>GO:0044427</title>
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<polygon style="fill:none;stroke:black;" points="941,-208 941,-238 1005,-238 1005,-208 941,-208"/>
<text text-anchor="middle" x="973" y="-227.667" style="font-family:Arial;font-size:10px;">chromosomal</text>
<text text-anchor="middle" x="973" y="-215.667" style="font-family:Arial;font-size:10px;">part</text>
</g>
<!-- GO:0044427&#45;&gt;GO:0000781 -->
<g id="edge281" class="edge"><title>GO:0044427&#45;&gt;GO:0000781</title>
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<polygon style="fill:gray;stroke:gray;" points="969.5,-198 973,-208 976.5,-198 969.5,-198"/>
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<!-- GO:0044454 -->
<g id="node126" class="node"><title>GO:0044454</title>
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<polygon style="fill:none;stroke:black;" points="1042,-94 1042,-124 1138,-124 1138,-94 1042,-94"/>
<text text-anchor="middle" x="1090" y="-113.667" style="font-family:Arial;font-size:10px;">nuclear chromosome</text>
<text text-anchor="middle" x="1090" y="-101.667" style="font-family:Arial;font-size:10px;">part</text>
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<!-- GO:0044427&#45;&gt;GO:0044454 -->
<g id="edge325" class="edge"><title>GO:0044427&#45;&gt;GO:0044454</title>
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<polygon style="fill:gray;stroke:gray;" points="989.2,-197.9 986,-208 994.8,-202.1 989.2,-197.9"/>
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<!-- GO:0044446 -->
<g id="node115" class="node"><title>GO:0044446</title>
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<polygon style="fill:none;stroke:black;" points="1158,-544 1158,-574 1222,-574 1222,-544 1158,-544"/>
<text text-anchor="middle" x="1190" y="-563.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="1190" y="-551.667" style="font-family:Arial;font-size:10px;">organelle part</text>
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<!-- GO:0044446&#45;&gt;GO:0044427 -->
<g id="edge283" class="edge"><title>GO:0044446&#45;&gt;GO:0044427</title>
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<!-- GO:0044446&#45;&gt;GO:0044428 -->
<g id="edge329" class="edge"><title>GO:0044446&#45;&gt;GO:0044428</title>
<path style="fill:none;stroke:gray;" d="M1191,-534C1194,-483 1197,-373 1199,-341"/>
<polygon style="fill:gray;stroke:gray;" points="1187.5,-534 1191,-544 1194.5,-534 1187.5,-534"/>
</g>
<!-- GO:0070013 -->
<g id="node138" class="node"><title>GO:0070013</title>
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<polygon style="fill:none;stroke:black;" points="1241,-428 1241,-458 1315,-458 1315,-428 1241,-428"/>
<text text-anchor="middle" x="1278" y="-447.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="1278" y="-435.667" style="font-family:Arial;font-size:10px;">organelle lumen</text>
</g>
<!-- GO:0044446&#45;&gt;GO:0070013 -->
<g id="edge411" class="edge"><title>GO:0044446&#45;&gt;GO:0070013</title>
<path style="fill:none;stroke:gray;" d="M1208,-536C1225,-512 1252,-478 1266,-458"/>
<polygon style="fill:gray;stroke:gray;" points="1205.2,-533.9 1202,-544 1210.8,-538.1 1205.2,-533.9"/>
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<!-- GO:0044422&#45;&gt;GO:0044446 -->
<g id="edge285" class="edge"><title>GO:0044422&#45;&gt;GO:0044446</title>
<path style="fill:none;stroke:gray;" d="M1234,-646C1224,-625 1207,-594 1198,-574"/>
<polygon style="fill:gray;stroke:gray;" points="1230.74,-647.283 1238,-655 1237.14,-644.44 1230.74,-647.283"/>
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<!-- GO:0043233 -->
<g id="node139" class="node"><title>GO:0043233</title>
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<polygon style="fill:none;stroke:black;" points="1256,-551 1256,-567 1330,-567 1330,-551 1256,-551"/>
<text text-anchor="middle" x="1293" y="-556.667" style="font-family:Arial;font-size:10px;">organelle lumen</text>
</g>
<!-- GO:0044422&#45;&gt;GO:0043233 -->
<g id="edge409" class="edge"><title>GO:0044422&#45;&gt;GO:0043233</title>
<path style="fill:none;stroke:gray;" d="M1250,-646C1262,-623 1280,-584 1289,-567"/>
<polygon style="fill:gray;stroke:gray;" points="1246.86,-644.44 1246,-655 1253.26,-647.283 1246.86,-644.44"/>
</g>
<!-- GO:0043226&#45;&gt;GO:0044422 -->
<g id="edge289" class="edge"><title>GO:0043226&#45;&gt;GO:0044422</title>
<path style="fill:none;stroke:blue;" d="M1078,-746C1087,-739 1098,-730 1109,-724 1129,-713 1135,-714 1155,-706 1181,-694 1209,-680 1227,-671"/>
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<!-- GO:0043229 -->
<g id="node122" class="node"><title>GO:0043229</title>
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<polygon style="fill:none;stroke:black;" points="1082,-648 1082,-678 1138,-678 1138,-648 1082,-648"/>
<text text-anchor="middle" x="1110" y="-667.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="1110" y="-655.667" style="font-family:Arial;font-size:10px;">organelle</text>
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<!-- GO:0043226&#45;&gt;GO:0043229 -->
<g id="edge309" class="edge"><title>GO:0043226&#45;&gt;GO:0043229</title>
<path style="fill:none;stroke:gray;" d="M1069,-744C1079,-726 1094,-696 1103,-678"/>
<polygon style="fill:gray;stroke:gray;" points="1065.86,-742.44 1065,-753 1072.26,-745.283 1065.86,-742.44"/>
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<!-- GO:0043228 -->
<g id="node125" class="node"><title>GO:0043228</title>
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<polygon style="fill:none;stroke:black;" points="812,-648 812,-678 922,-678 922,-648 812,-648"/>
<text text-anchor="middle" x="867" y="-667.667" style="font-family:Arial;font-size:10px;">non&#45;membrane&#45;bounded</text>
<text text-anchor="middle" x="867" y="-655.667" style="font-family:Arial;font-size:10px;">organelle</text>
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<!-- GO:0043226&#45;&gt;GO:0043228 -->
<g id="edge319" class="edge"><title>GO:0043226&#45;&gt;GO:0043228</title>
<path style="fill:none;stroke:gray;" d="M1033,-749C1007,-739 971,-722 939,-706 923,-697 905,-687 891,-678"/>
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<!-- GO:0043227 -->
<g id="node129" class="node"><title>GO:0043227</title>
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<polygon style="fill:none;stroke:black;" points="956,-648 956,-678 1048,-678 1048,-648 956,-648"/>
<text text-anchor="middle" x="1002" y="-667.667" style="font-family:Arial;font-size:10px;">membrane&#45;bounded</text>
<text text-anchor="middle" x="1002" y="-655.667" style="font-family:Arial;font-size:10px;">organelle</text>
</g>
<!-- GO:0043226&#45;&gt;GO:0043227 -->
<g id="edge337" class="edge"><title>GO:0043226&#45;&gt;GO:0043227</title>
<path style="fill:none;stroke:gray;" d="M1051,-744C1040,-726 1022,-696 1011,-678"/>
<polygon style="fill:gray;stroke:gray;" points="1048.08,-745.958 1056,-753 1054.2,-742.559 1048.08,-745.958"/>
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<!-- GO:0044424 -->
<g id="node118" class="node"><title>GO:0044424</title>
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<text text-anchor="middle" x="1154" y="-765.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="1154" y="-753.667" style="font-family:Arial;font-size:10px;">part</text>
</g>
<!-- GO:0044424&#45;&gt;GO:0044446 -->
<g id="edge293" class="edge"><title>GO:0044424&#45;&gt;GO:0044446</title>
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<!-- GO:0044424&#45;&gt;GO:0043229 -->
<g id="edge311" class="edge"><title>GO:0044424&#45;&gt;GO:0043229</title>
<path style="fill:none;stroke:gray;" d="M1143,-737C1135,-718 1124,-694 1117,-678"/>
<polygon style="fill:gray;stroke:gray;" points="1139.74,-738.283 1147,-746 1146.14,-735.44 1139.74,-738.283"/>
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<!-- GO:0044464&#45;&gt;GO:0044424 -->
<g id="edge295" class="edge"><title>GO:0044464&#45;&gt;GO:0044424</title>
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<!-- GO:0005622 -->
<g id="node121" class="node"><title>GO:0005622</title>
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<polygon style="fill:none;stroke:black;" points="1097,-833 1097,-849 1153,-849 1153,-833 1097,-833"/>
<text text-anchor="middle" x="1125" y="-838.667" style="font-family:Arial;font-size:10px;">intracellular</text>
</g>
<!-- GO:0044464&#45;&gt;GO:0005622 -->
<g id="edge305" class="edge"><title>GO:0044464&#45;&gt;GO:0005622</title>
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<!-- GO:0005623&#45;&gt;GO:0044464 -->
<g id="edge299" class="edge"><title>GO:0005623&#45;&gt;GO:0044464</title>
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<g id="edge303" class="edge"><title>GO:0005622&#45;&gt;GO:0044424</title>
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<!-- GO:0043229&#45;&gt;GO:0044446 -->
<g id="edge307" class="edge"><title>GO:0043229&#45;&gt;GO:0044446</title>
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<!-- GO:0043232 -->
<g id="node124" class="node"><title>GO:0043232</title>
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<polygon style="fill:none;stroke:black;" points="888,-538 888,-580 998,-580 998,-538 888,-538"/>
<text text-anchor="middle" x="943" y="-569.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="943" y="-557.667" style="font-family:Arial;font-size:10px;">non&#45;membrane&#45;bounded</text>
<text text-anchor="middle" x="943" y="-545.667" style="font-family:Arial;font-size:10px;">organelle</text>
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<!-- GO:0043229&#45;&gt;GO:0043232 -->
<g id="edge321" class="edge"><title>GO:0043229&#45;&gt;GO:0043232</title>
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<!-- GO:0043231 -->
<g id="node128" class="node"><title>GO:0043231</title>
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<polygon style="fill:none;stroke:black;" points="1032,-538 1032,-580 1124,-580 1124,-538 1032,-538"/>
<text text-anchor="middle" x="1078" y="-569.667" style="font-family:Arial;font-size:10px;">intracellular</text>
<text text-anchor="middle" x="1078" y="-557.667" style="font-family:Arial;font-size:10px;">membrane&#45;bounded</text>
<text text-anchor="middle" x="1078" y="-545.667" style="font-family:Arial;font-size:10px;">organelle</text>
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<!-- GO:0043229&#45;&gt;GO:0043231 -->
<g id="edge339" class="edge"><title>GO:0043229&#45;&gt;GO:0043231</title>
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<!-- GO:0005694 -->
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<text text-anchor="middle" x="973" y="-330.667" style="font-family:Arial;font-size:10px;">chromosome</text>
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<!-- GO:0005694&#45;&gt;GO:0044427 -->
<g id="edge313" class="edge"><title>GO:0005694&#45;&gt;GO:0044427</title>
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<!-- GO:0000228 -->
<g id="node130" class="node"><title>GO:0000228</title>
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<polygon style="fill:none;stroke:black;" points="1039,-215 1039,-231 1135,-231 1135,-215 1039,-215"/>
<text text-anchor="middle" x="1087" y="-220.667" style="font-family:Arial;font-size:10px;">nuclear chromosome</text>
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<!-- GO:0005694&#45;&gt;GO:0000228 -->
<g id="edge343" class="edge"><title>GO:0005694&#45;&gt;GO:0000228</title>
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<g id="edge315" class="edge"><title>GO:0043232&#45;&gt;GO:0005694</title>
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</g>
<!-- GO:0043228&#45;&gt;GO:0043232 -->
<g id="edge317" class="edge"><title>GO:0043228&#45;&gt;GO:0043232</title>
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<!-- GO:0044454&#45;&gt;GO:0000784 -->
<g id="edge323" class="edge"><title>GO:0044454&#45;&gt;GO:0000784</title>
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<polygon style="fill:gray;stroke:gray;" points="1070.2,-88.1 1079,-94 1075.8,-83.9 1070.2,-88.1"/>
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<!-- GO:0044428&#45;&gt;GO:0000109 -->
<g id="edge353" class="edge"><title>GO:0044428&#45;&gt;GO:0000109</title>
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<!-- GO:0044428&#45;&gt;GO:0005654 -->
<g id="edge395" class="edge"><title>GO:0044428&#45;&gt;GO:0005654</title>
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<!-- GO:0044428&#45;&gt;GO:0044454 -->
<g id="edge327" class="edge"><title>GO:0044428&#45;&gt;GO:0044454</title>
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<!-- GO:0044428&#45;&gt;GO:0000228 -->
<g id="edge345" class="edge"><title>GO:0044428&#45;&gt;GO:0000228</title>
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<polygon style="fill:gray;stroke:gray;" points="1181.45,-320.404 1191,-325 1186.4,-315.454 1181.45,-320.404"/>
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<!-- GO:0031981 -->
<g id="node137" class="node"><title>GO:0031981</title>
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<polygon style="fill:none;stroke:black;" points="1245,-215 1245,-231 1311,-231 1311,-215 1245,-215"/>
<text text-anchor="middle" x="1278" y="-220.667" style="font-family:Arial;font-size:10px;">nuclear lumen</text>
</g>
<!-- GO:0044428&#45;&gt;GO:0031981 -->
<g id="edge399" class="edge"><title>GO:0044428&#45;&gt;GO:0031981</title>
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<polygon style="fill:gray;stroke:gray;" points="1208.2,-314.9 1205,-325 1213.8,-319.1 1208.2,-314.9"/>
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<!-- GO:0043231&#45;&gt;GO:0005634 -->
<g id="edge333" class="edge"><title>GO:0043231&#45;&gt;GO:0005634</title>
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<polygon style="fill:gray;stroke:gray;" points="1074.5,-528 1078,-538 1081.5,-528 1074.5,-528"/>
</g>
<!-- GO:0043227&#45;&gt;GO:0043231 -->
<g id="edge335" class="edge"><title>GO:0043227&#45;&gt;GO:0043231</title>
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<!-- GO:0000228&#45;&gt;GO:0044454 -->
<g id="edge341" class="edge"><title>GO:0000228&#45;&gt;GO:0044454</title>
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<polygon style="fill:blue;stroke:blue;" points="1083.5,-205 1087,-215 1090.5,-205 1083.5,-205"/>
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<!-- GO:0032991&#45;&gt;GO:0043234 -->
<g id="edge349" class="edge"><title>GO:0032991&#45;&gt;GO:0043234</title>
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<polygon style="fill:gray;stroke:gray;" points="1419.61,-934.881 1425,-944 1426.47,-933.508 1419.61,-934.881"/>
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<!-- GO:0045002 -->
<g id="node132" class="node"><title>GO:0045002</title>
<polygon style="fill:white;stroke:white;" points="4129,-306 4129,-360 4205,-360 4205,-306 4129,-306"/>
<polygon style="fill:none;stroke:black;" points="4129,-306 4129,-360 4205,-360 4205,-306 4129,-306"/>
<text text-anchor="middle" x="4167" y="-349.667" style="font-family:Arial;font-size:10px;">double&#45;strand</text>
<text text-anchor="middle" x="4167" y="-337.667" style="font-family:Arial;font-size:10px;">break repair</text>
<text text-anchor="middle" x="4167" y="-325.667" style="font-family:Arial;font-size:10px;">via single&#45;strand</text>
<text text-anchor="middle" x="4167" y="-313.667" style="font-family:Arial;font-size:10px;">annealing</text>
</g>
<!-- GO:0045002&#45;&gt;GO:0000736 -->
<g id="edge357" class="edge"><title>GO:0045002&#45;&gt;GO:0000736</title>
<path style="fill:none;stroke:blue;" d="M4136,-298C4128,-289 4119,-278 4110,-268"/>
<polygon style="fill:blue;stroke:blue;" points="4133.78,-300.779 4143,-306 4139.05,-296.169 4133.78,-300.779"/>
</g>
<!-- GO:0000726&#45;&gt;GO:0045002 -->
<g id="edge359" class="edge"><title>GO:0000726&#45;&gt;GO:0045002</title>
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<polygon style="fill:gray;stroke:gray;" points="4250.78,-422.779 4260,-428 4256.05,-418.169 4250.78,-422.779"/>
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<!-- GO:0006302&#45;&gt;GO:0000724 -->
<g id="edge419" class="edge"><title>GO:0006302&#45;&gt;GO:0000724</title>
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<polygon style="fill:gray;stroke:gray;" points="4139.78,-422.779 4149,-428 4145.05,-418.169 4139.78,-422.779"/>
</g>
<!-- GO:0006302&#45;&gt;GO:0045002 -->
<g id="edge363" class="edge"><title>GO:0006302&#45;&gt;GO:0045002</title>
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<polygon style="fill:gray;stroke:gray;" points="4160.51,-417.701 4163,-428 4167.48,-418.398 4160.51,-417.701"/>
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<!-- GO:0051307&#45;&gt;GO:0000712 -->
<g id="edge367" class="edge"><title>GO:0051307&#45;&gt;GO:0000712</title>
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<polygon style="fill:gray;stroke:gray;" points="1621.08,-200.958 1629,-208 1627.2,-197.559 1621.08,-200.958"/>
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<!-- GO:0051304&#45;&gt;GO:0051307 -->
<g id="edge369" class="edge"><title>GO:0051304&#45;&gt;GO:0051307</title>
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<!-- GO:0031981&#45;&gt;GO:0005654 -->
<g id="edge397" class="edge"><title>GO:0031981&#45;&gt;GO:0005654</title>
<path style="fill:none;stroke:blue;" d="M1273,-205C1266,-183 1255,-145 1249,-124"/>
<polygon style="fill:blue;stroke:blue;" points="1269.77,-206.427 1276,-215 1276.48,-204.416 1269.77,-206.427"/>
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<!-- GO:0070013&#45;&gt;GO:0031981 -->
<g id="edge401" class="edge"><title>GO:0070013&#45;&gt;GO:0031981</title>
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<polygon style="fill:gray;stroke:gray;" points="1274.5,-418 1278,-428 1281.5,-418 1274.5,-418"/>
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<!-- GO:0043233&#45;&gt;GO:0070013 -->
<g id="edge403" class="edge"><title>GO:0043233&#45;&gt;GO:0070013</title>
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<polygon style="fill:gray;stroke:gray;" points="1287.52,-541.398 1292,-551 1294.49,-540.701 1287.52,-541.398"/>
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<!-- GO:0031974&#45;&gt;GO:0043233 -->
<g id="edge405" class="edge"><title>GO:0031974&#45;&gt;GO:0043233</title>
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<!-- GO:0000725&#45;&gt;GO:0000724 -->
<g id="edge413" class="edge"><title>GO:0000725&#45;&gt;GO:0000724</title>
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<!-- GO:0046983&#45;&gt;GO:0046982 -->
<g id="edge421" class="edge"><title>GO:0046983&#45;&gt;GO:0046982</title>
<path style="fill:none;stroke:gray;" d="M287,-816C285,-808 283,-799 281,-792"/>
<polygon style="fill:gray;stroke:gray;" points="283.607,-816.881 289,-826 290.471,-815.508 283.607,-816.881"/>
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<!-- GO:0010639 -->
<g id="node143" class="node"><title>GO:0010639</title>
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<polygon style="fill:none;stroke:black;" points="2249,-538 2249,-580 2335,-580 2335,-538 2249,-538"/>
<text text-anchor="middle" x="2292" y="-569.667" style="font-family:Arial;font-size:10px;">negative regulation</text>
<text text-anchor="middle" x="2292" y="-557.667" style="font-family:Arial;font-size:10px;">of organelle</text>
<text text-anchor="middle" x="2292" y="-545.667" style="font-family:Arial;font-size:10px;">organization</text>
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<!-- GO:0010639&#45;&gt;GO:0032205 -->
<g id="edge429" class="edge"><title>GO:0010639&#45;&gt;GO:0032205</title>
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<polygon style="fill:gray;stroke:gray;" points="2304.8,-527.559 2303,-538 2310.92,-530.958 2304.8,-527.559"/>
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<!-- GO:0033043 -->
<g id="node144" class="node"><title>GO:0033043</title>
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<text text-anchor="middle" x="2401" y="-667.667" style="font-family:Arial;font-size:10px;">regulation of</text>
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<!-- GO:0033043&#45;&gt;GO:0010639 -->
<g id="edge431" class="edge"><title>GO:0033043&#45;&gt;GO:0010639</title>
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<polygon style="fill:gray;stroke:gray;" points="2375.45,-643.404 2385,-648 2380.4,-638.454 2375.45,-643.404"/>
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<!-- GO:0033044 -->
<g id="node158" class="node"><title>GO:0033044</title>
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<!-- GO:0033043&#45;&gt;GO:0033044 -->
<g id="edge489" class="edge"><title>GO:0033043&#45;&gt;GO:0033044</title>
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<!-- GO:0051128 -->
<g id="node145" class="node"><title>GO:0051128</title>
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<text text-anchor="middle" x="2289" y="-771.667" style="font-family:Arial;font-size:10px;">regulation of</text>
<text text-anchor="middle" x="2289" y="-759.667" style="font-family:Arial;font-size:10px;">cellular component</text>
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<!-- GO:0051128&#45;&gt;GO:0033043 -->
<g id="edge433" class="edge"><title>GO:0051128&#45;&gt;GO:0033043</title>
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<polygon style="fill:gray;stroke:gray;" points="2317.6,-730.454 2313,-740 2322.55,-735.404 2317.6,-730.454"/>
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<!-- GO:0051129 -->
<g id="node151" class="node"><title>GO:0051129</title>
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<polygon style="fill:none;stroke:black;" points="2207,-642 2207,-684 2317,-684 2317,-642 2207,-642"/>
<text text-anchor="middle" x="2262" y="-673.667" style="font-family:Arial;font-size:10px;">negative regulation</text>
<text text-anchor="middle" x="2262" y="-661.667" style="font-family:Arial;font-size:10px;">of cellular</text>
<text text-anchor="middle" x="2262" y="-649.667" style="font-family:Arial;font-size:10px;">component organization</text>
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<!-- GO:0051128&#45;&gt;GO:0051129 -->
<g id="edge469" class="edge"><title>GO:0051128&#45;&gt;GO:0051129</title>
<path style="fill:none;stroke:gray;" d="M2280,-730C2276,-715 2271,-698 2268,-684"/>
<polygon style="fill:gray;stroke:gray;" points="2276.77,-731.427 2283,-740 2283.48,-729.416 2276.77,-731.427"/>
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<!-- GO:0050794&#45;&gt;GO:0051128 -->
<g id="edge435" class="edge"><title>GO:0050794&#45;&gt;GO:0051128</title>
<path style="fill:none;stroke:gray;" d="M2611,-822C2605,-819 2599,-817 2593,-816 2504,-792 2477,-818 2388,-798 2370,-794 2350,-787 2333,-780"/>
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<!-- GO:0050794&#45;&gt;GO:0048523 -->
<g id="edge465" class="edge"><title>GO:0050794&#45;&gt;GO:0048523</title>
<path style="fill:none;stroke:gray;" d="M2656,-816C2660,-806 2664,-793 2668,-782"/>
<polygon style="fill:gray;stroke:gray;" points="2652.46,-815.415 2652,-826 2658.96,-818.015 2652.46,-815.415"/>
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<!-- GO:0050794&#45;&gt;GO:0031323 -->
<g id="edge507" class="edge"><title>GO:0050794&#45;&gt;GO:0031323</title>
<path style="fill:none;stroke:gray;" d="M2694,-832C2753,-820 2848,-801 2856,-798 2866,-794 2876,-788 2885,-782"/>
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<!-- GO:0050789&#45;&gt;GO:0050794 -->
<g id="edge437" class="edge"><title>GO:0050789&#45;&gt;GO:0050794</title>
<path style="fill:none;stroke:gray;" d="M2620,-880C2626,-872 2632,-863 2636,-856"/>
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<!-- GO:0050789&#45;&gt;GO:0048519 -->
<g id="edge461" class="edge"><title>GO:0050789&#45;&gt;GO:0048519</title>
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<g id="edge447" class="edge"><title>GO:0016043&#45;&gt;GO:0051128</title>
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<g id="edge473" class="edge"><title>GO:0006996&#45;&gt;GO:0010639</title>
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<g id="edge451" class="edge"><title>GO:0006996&#45;&gt;GO:0033043</title>
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<g id="edge493" class="edge"><title>GO:0006996&#45;&gt;GO:0051276</title>
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<g id="edge455" class="edge"><title>GO:0051129&#45;&gt;GO:0010639</title>
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<g id="edge457" class="edge"><title>GO:0048523&#45;&gt;GO:0051129</title>
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<g id="edge567" class="edge"><title>GO:0048523&#45;&gt;GO:0031324</title>
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<g id="edge459" class="edge"><title>GO:0048519&#45;&gt;GO:0048523</title>
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<text text-anchor="middle" x="2054" y="-673.667" style="font-family:Arial;font-size:10px;">negative regulation</text>
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<!-- GO:0048519&#45;&gt;GO:0032845 -->
<g id="edge537" class="edge"><title>GO:0048519&#45;&gt;GO:0032845</title>
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<g id="edge549" class="edge"><title>GO:0048519&#45;&gt;GO:0009892</title>
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<!-- GO:0032204&#45;&gt;GO:0032205 -->
<g id="edge475" class="edge"><title>GO:0032204&#45;&gt;GO:0032205</title>
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<g id="edge535" class="edge"><title>GO:0032844&#45;&gt;GO:0032845</title>
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<g id="edge481" class="edge"><title>GO:0042592&#45;&gt;GO:0032844</title>
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<g id="edge531" class="edge"><title>GO:0042592&#45;&gt;GO:0060249</title>
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<g id="edge539" class="edge"><title>GO:0042592&#45;&gt;GO:0032845</title>
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<g id="edge483" class="edge"><title>GO:0065008&#45;&gt;GO:0042592</title>
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<g id="edge487" class="edge"><title>GO:0033044&#45;&gt;GO:0032204</title>
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<g id="edge491" class="edge"><title>GO:0051276&#45;&gt;GO:0033044</title>
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<g id="edge527" class="edge"><title>GO:0051276&#45;&gt;GO:0032200</title>
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<g id="edge573" class="edge"><title>GO:0051052&#45;&gt;GO:0051053</title>
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<g id="edge565" class="edge"><title>GO:0031323&#45;&gt;GO:0031324</title>
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