Compare GO annotations for ERCC4 and its Reference Genomes orthologs

Compare GO annotations for ERCC4 and its orthologs

Possible outliers might be spotted in a summary/comparison table of high level GO categories.
Complete table of the annotations represented in this image is provided below.

Annotations are indicated by colored nodes: human, mouse, rat, chicken, zfish, fly, worm, dicty, dicot, yeast, pombe, ecoli.
Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Red arrows indicate "regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Chicken from GOA; Zfish from Zfin; Fly from Flybase; Worm from Wormbase; Dicot from TAIR; Dicty from Dictybase; Yeast from SGD; Pombe from Sanger; Ecoli from EcoliHub.
Organisms with experimental annotations are indicated: IC, IDA, IEP, IGI, IMP, IPI. In addition, ISS annotations are so indicated.
Does not include evidence codes: IEA, IGC, NAS, ND, NR, RCA, TAS.
Graph is also available as SVG (requires viewer plug-in from Adobe)
Evidence codes are listed at the bottom of the page.
Graph generated Tue Oct 21 07:00:30 2008.

Compare annotations to GO categories for ERCC4.

Entry indicates that ortholog exists for this gene.
Colored entries indicate experimental annotation.
Parentheses indicate ISS annotation only.

Category	ID	Term	Human	Mouse	Rat	Chicken	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	Ecoli
Molecular Function	GO:0005488	binding	Human	Mouse	Rat	X	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	X
Molecular Function	GO:0003824	catalytic activity	Human	Mouse	Rat	X	Zfish	(Fly)	Worm	(Dicty)	Dicot	Yeast	(Pombe)	X
Cellular Component	GO:0005623	cell	Human	(Mouse)	Rat	X	Zfish	Fly	Worm	(Dicty)	Dicot	Yeast	Pombe	X
Cellular Component	GO:0044464	cell part	Human	(Mouse)	Rat	X	Zfish	Fly	Worm	(Dicty)	Dicot	Yeast	Pombe	X
Cellular Component	GO:0032991	macromolecular complex	Human	(Mouse)	Rat	X	Zfish	Fly	Worm	(Dicty)	Dicot	Yeast	(Pombe)	X
Cellular Component	GO:0031974	membrane-enclosed lumen	(Human)	Mouse	Rat	X	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	X
Cellular Component	GO:0043226	organelle	Human	(Mouse)	Rat	X	Zfish	Fly	Worm	(Dicty)	Dicot	Yeast	Pombe	X
Cellular Component	GO:0044422	organelle part	Human	(Mouse)	Rat	X	Zfish	Fly	Worm	(Dicty)	Dicot	Yeast	(Pombe)	X
Biological Process	GO:0065007	biological regulation	Human	Mouse	Rat	X	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	X
Biological Process	GO:0009987	cellular process	Human	Mouse	Rat	X	Zfish	Fly	Worm	(Dicty)	Dicot	Yeast	Pombe	X
Biological Process	GO:0032502	developmental process	Human	Mouse	Rat	X	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	X
Biological Process	GO:0008152	metabolic process	Human	Mouse	Rat	X	Zfish	Fly	Worm	(Dicty)	Dicot	Yeast	Pombe	X
Biological Process	GO:0032501	multicellular organismal process	Human	Mouse	Rat	X	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	X
Biological Process	GO:0048519	negative regulation of biological process	Human	Mouse	Rat	X	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	X
Biological Process	GO:0050789	regulation of biological process	Human	Mouse	Rat	X	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	X
Biological Process	GO:0000003	reproduction	Human	Mouse	Rat	X	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	X
Biological Process	GO:0022414	reproductive process	Human	Mouse	Rat	X	Zfish	Fly	Worm	Dicty	Dicot	Yeast	Pombe	X
Biological Process	GO:0050896	response to stimulus	Human	Mouse	Rat	X	Zfish	Fly	Worm	(Dicty)	Dicot	Yeast	Pombe	X

Full set of experimental (and ISS) annotations for ERCC4

Category	ID	Term	DB Object	Evidence	With_From	Organism	Reference
Molecular Function	GO:0003684	damaged DNA binding	ERCC4	IMP		Human	PMID:11790111
Molecular Function	GO:0003677	DNA binding	rad16	ISS	SGD:S000005943	Pombe	PMID:17072883
Molecular Function	GO:0004520	endodeoxyribonuclease activity	ERCC4	IDA		Human	PMID:10413517
Molecular Function	GO:0004520	endodeoxyribonuclease activity	ERCC4	IDA		Human	PMID:14734547
Molecular Function	GO:0004520	endodeoxyribonuclease activity	ERCC4	IDA		Human	PMID:8797827
Molecular Function	GO:0004520	endodeoxyribonuclease activity	mei-9	ISS	MGI:MGI:1354163	Fly	FB:FBrf0105495
Molecular Function	GO:0004520	endodeoxyribonuclease activity	mei-9	ISS	UniProtKB:Q92889	Fly	FB:FBrf0105495
Molecular Function	GO:0005515	protein binding	mei-9	IPI	FB:FBgn0028434	Fly	FB:FBrf0155944\|PMID:12504024
Molecular Function	GO:0005515	protein binding	mei-9	IPI	FB:FBgn0002909	Fly	FB:FBrf0155944\|PMID:12504024
Molecular Function	GO:0008022	protein C-terminus binding	ERCC4	IPI	UniProtKB:P07992	Human	PMID:9722633
Molecular Function	GO:0046982	protein heterodimerization activity	mei-9	IPI	FB:FBgn0028434	Fly	FB:FBrf0128640\|PMID:10812334
Molecular Function	GO:0046982	protein heterodimerization activity	rad16	IPI	GeneDB_Spombe:SPBC4F6.15c	Pombe	PMID:8114734
Molecular Function	GO:0047485	protein N-terminus binding	ERCC4	IPI	UniProtKB:P43351	Human	PMID:14734547
Molecular Function	GO:0003697	single-stranded DNA binding	ERCC4	IDA		Human	PMID:10413517
Molecular Function	GO:0003697	single-stranded DNA binding	RAD1	IDA		Yeast	SGD_REF:S000046088\|PMID:8253764
Molecular Function	GO:0000014	single-stranded DNA specific endodeoxyribonuclease activity	ercc4	ISS	SGD:S000005943	Dicty	dictyBase_REF:10155
Molecular Function	GO:0000014	single-stranded DNA specific endodeoxyribonuclease activity	RAD1	IDA		Yeast	SGD_REF:S000046088\|PMID:8253764
Molecular Function	GO:0000014	single-stranded DNA specific endodeoxyribonuclease activity	rad16	ISS	UniProtKB:P06777	Pombe	PMID:17072883
Cellular Component	GO:0000784	nuclear chromosome, telomeric region	ERCC4	IDA		Human	PMID:14690602
Cellular Component	GO:0005654	nucleoplasm	ERCC4	EXP		Human	PMID:11313499
Cellular Component	GO:0005654	nucleoplasm	ERCC4	EXP		Human	PMID:10214908
Cellular Component	GO:0000109	nucleotide-excision repair complex	ERCC4	IDA		Human	PMID:10413517
Cellular Component	GO:0000109	nucleotide-excision repair complex	Ercc4	ISO	UniProtKB:Q92889	Mouse	MGI:MGI:1353092\|PMID:10644440
Cellular Component	GO:0000109	nucleotide-excision repair complex	rad16	ISS	UniProtKB:P06777	Pombe	PMID:17072883
Cellular Component	GO:0000110	nucleotide-excision repair factor 1 complex	ercc4	ISS	SGD:S000005943	Dicty	dictyBase_REF:10155
Cellular Component	GO:0000110	nucleotide-excision repair factor 1 complex	RAD1	IPI	SGD:S000004560\|SGD:S000004814	Yeast	SGD_REF:S000053761\|PMID:8621533
Cellular Component	GO:0005634	nucleus	ERCC4	IDA		Human	PMID:12571280
Cellular Component	GO:0005634	nucleus	RAD1	IDA		Yeast	SGD_REF:S000047071\|PMID:9852079
Cellular Component	GO:0005634	nucleus	rad16	IC	GO:0000014	Pombe	PMID:17072883
Cellular Component	GO:0005634	nucleus	rad16	IDA		Pombe	PMID:16823372
Cellular Component	GO:0043234	protein complex	mei-9	IDA		Fly	FB:FBrf0187655\|PMID:15944364
Biological Process	GO:0006281	DNA repair	Ercc4	IMP	MGI:MGI:3028660	Mouse	MGI:MGI:3027419\|PMID:14729965
Biological Process	GO:0000724	double-strand break repair via homologous recombination	ERCC4	IMP		Human	PMID:14728600
Biological Process	GO:0000736	double-strand break repair via single-strand annealing, removal of nonhomologous ends	RAD1	IMP		Yeast	SGD_REF:S000051157\|PMID:1411547
Biological Process	GO:0000736	double-strand break repair via single-strand annealing, removal of nonhomologous ends	RAD1	IMP		Yeast	SGD_REF:S000046045\|PMID:7891718
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	C47D12.8	IMP	WB:WBRNAi00036116\|WB:WBPhenotype:0000050	Worm	WB:WBPaper00024497\|PMID:15489339
Biological Process	GO:0009792	embryonic development ending in birth or egg hatching	C47D12.8	IMP	WB:WBRNAi00061508\|WB:WBPhenotype:0000050	Worm	WB:WBPaper00024925\|PMID:15687288
Biological Process	GO:0016321	female meiosis chromosome segregation	mei-9	IMP		Fly	FB:FBrf0023919\|PMID:4625747
Biological Process	GO:0007534	gene conversion at mating-type locus	rad16	IMP		Pombe	PMID:12628934
Biological Process	GO:0045132	meiotic chromosome segregation	mei-9	IMP		Fly	FB:FBrf0155944\|PMID:12504024
Biological Process	GO:0006311	meiotic gene conversion	rad16	IMP		Pombe	PMID:12628934
Biological Process	GO:0000710	meiotic mismatch repair	RAD1	IMP		Yeast	SGD_REF:S000061201\|PMID:11514439
Biological Process	GO:0007131	meiotic recombination	mei-9	IMP		Fly	FB:FBrf0023919\|PMID:4625747
Biological Process	GO:0007131	meiotic recombination	mei-9	IMP		Fly	FB:FBrf0155944\|PMID:12504024
Biological Process	GO:0006298	mismatch repair	mei-9	IMP		Fly	FB:FBrf0100533\|PMID:9488459
Biological Process	GO:0006312	mitotic recombination	RAD1	IMP		Yeast	SGD_REF:S000052152\|PMID:3065620
Biological Process	GO:0032205	negative regulation of telomere maintenance	ERCC4	IMP		Human	PMID:17055345
Biological Process	GO:0006289	nucleotide-excision repair	Ercc4	ISO	UniProtKB:Q92889	Mouse	MGI:MGI:1353092\|PMID:10644440
Biological Process	GO:0006289	nucleotide-excision repair	mei-9	IMP		Fly	FB:FBrf0028769\|PMID:826452
Biological Process	GO:0006289	nucleotide-excision repair	mei-9	ISS		Fly	FB:FBrf0084352\|PMID:8647398
Biological Process	GO:0006289	nucleotide-excision repair	rad16	IGI	GeneDB_Spombe:SPBC3E7.08c	Pombe	PMID:8709952
Biological Process	GO:0000718	nucleotide-excision repair, DNA damage removal	ERCC4	EXP		Human	PMID:10583946
Biological Process	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion	ERCC4	IMP		Human	PMID:11790111
Biological Process	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	ERCC4	IMP		Human	PMID:14728600
Biological Process	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	ERCC4	IMP		Human	PMID:11790111
Biological Process	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	ercc4	ISS	SGD:S000005943	Dicty	dictyBase_REF:10155
Biological Process	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	RAD1	IDA		Yeast	SGD_REF:S000045969\|PMID:7559571
Biological Process	GO:0000735	removal of nonhomologous ends	RAD1	IMP		Yeast	SGD_REF:S000051157\|PMID:1411547
Biological Process	GO:0000735	removal of nonhomologous ends	RAD1	IMP		Yeast	SGD_REF:S000046045\|PMID:7891718
Biological Process	GO:0000712	resolution of meiotic joint molecules as recombinants	mei-9	IMP		Fly	FB:FBrf0201675\|PMID:17339219
Biological Process	GO:0006974	response to DNA damage stimulus	C47D12.8	IMP	WB:vc19\|WB:vc67	Worm	WB:WBPaper00028727
Biological Process	GO:0009650	UV protection	Ercc4	IMP	MGI:MGI:3028660	Mouse	MGI:MGI:3027419\|PMID:14729965

Gene Ontology Evidence Code Abbreviations:

IC Inferred by curator

IDA Inferred from direct assay

IEA Inferred from electronic annotation

IEP Inferred from expression pattern

IGC Inferred from genomic context

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

NAS Non-traceable Author Statement

ND No biological data available

RCA Reviewed computational analysis

TAS Traceable author statement

NR Not recorded (appears in some legacy annotations)