GO annotation of autism relevant proteins

A UCL Genetics of Human Disease MSc student spent several months focusing on the annotation of 17 human proteins associated with autism, as well as many of the orthologous proteins. The result of this annotation project is now published (http://www.ncbi.nlm.nih.gov/pubmed/?term=26047810) and demonstrates how a focused annotation approach leads to the creation of more descriptive Gene Ontology (GO) terms, as well as an increase in both the number of gene product annotations and their granularity, thus improving the data available in the GO database.