format-version: 1.2 date: 15:08:2011 17:04 auto-generated-by: OBO-Edit 2.0 ontology: go saved-by: kchris synonymtypedef: systematic_synonym "Systematic synonym" EXACT subsetdef: goslim_candida "Candida GO slim" subsetdef: goslim_generic "Generic GO slim" subsetdef: goslim_pir "PIR GO slim" subsetdef: goslim_plant "Plant GO slim" subsetdef: goslim_pombe "Fission yeast GO slim" subsetdef: goslim_yeast "Yeast GO slim" subsetdef: gosubset_prok "Prokaryotic GO subset" subsetdef: high_level_annotation_qc "High-level terms not to be used for direct annotation" subsetdef: unvetted "unvetted" remark: cvs version: $Revision: 1.101 $ [Term] id: GO:0000747 name: conjugation with cellular fusion namespace: biological_process alt_id: GO:0007322 alt_id: GO:0007333 alt_id: GO:0030461 alt_id: GO:0030477 def: "A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae." [GOC:elh] subset: goslim_pombe synonym: "cell fusion" RELATED [] synonym: "mating" RELATED [] is_a: GO:0008150 ! biological_process [Term] id: GO:0000910 name: cytokinesis namespace: biological_process alt_id: GO:0007104 alt_id: GO:0016288 def: "A cellular process resulting in the division of the cytoplasm of a cell and its separation into two daughter cells. Cytokinesis usually occurs after growth, replication, and segregation of cellular components." [GOC:ai] comment: Note that most eukaryotic gene products involved in canonical cytokinesis during the cell cycle can be annotated to 'cell cycle cytokinesis ; GO:0033205' or its descendants. See also 'cell division ; GO:0051301'. Note that cytokinesis excludes nuclear division; in prokaryotes, there is little difference between cytokinesis and cell division. subset: goslim_candida subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok xref: Reactome:REACT_101918 ! Mitotic Telophase /Cytokinesis, Mus musculus xref: Reactome:REACT_108805 ! Mitotic Telophase /Cytokinesis, Dictyostelium discoideum xref: Reactome:REACT_1932 ! Mitotic Telophase /Cytokinesis, Homo sapiens xref: Reactome:REACT_30667 ! Mitotic Telophase /Cytokinesis, Schizosaccharomyces pombe xref: Reactome:REACT_32636 ! Mitotic Telophase /Cytokinesis, Bos taurus xref: Reactome:REACT_78494 ! Mitotic Telophase /Cytokinesis, Danio rerio xref: Reactome:REACT_84722 ! Mitotic Telophase /Cytokinesis, Gallus gallus xref: Reactome:REACT_87726 ! Mitotic Telophase /Cytokinesis, Xenopus tropicalis xref: Reactome:REACT_92849 ! Mitotic Telophase /Cytokinesis, Taeniopygia guttata xref: Reactome:REACT_93374 ! Mitotic Telophase /Cytokinesis, Canis familiaris xref: Reactome:REACT_94382 ! Mitotic Telophase /Cytokinesis, Drosophila melanogaster xref: Reactome:REACT_98952 ! Mitotic Telophase /Cytokinesis, Rattus norvegicus xref: Reactome:REACT_99118 ! Mitotic Telophase /Cytokinesis, Caenorhabditis elegans xref: Wikipedia:Cytokinesis is_a: GO:0008150 ! biological_process relationship: part_of GO:0008150 ! biological_process [Term] id: GO:0002181 name: cytoplasmic translation namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein." [GOC:hjd] subset: goslim_pombe subset: goslim_yeast is_a: GO:0008150 ! biological_process relationship: part_of GO:0008150 ! biological_process created_by: hjd creation_date: 2011-06-09T03:11:53Z [Term] id: GO:0005575 name: cellular_component namespace: cellular_component alt_id: GO:0008372 def: "The part of a cell or its extracellular environment in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together." [GOC:go_curators] comment: Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. Note that when this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this. subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "cellular component" EXACT [] synonym: "cellular component unknown" NARROW [] xref: NIF_Subcellular:sao1337158144 disjoint_from: GO:0003674 ! molecular_function [Term] id: GO:0005975 name: carbohydrate metabolic process namespace: biological_process def: "The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule." [GOC:mah, ISBN:0198506732] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "carbohydrate metabolism" EXACT [] xref: Reactome:REACT_101193 ! Metabolism of carbohydrates, Sus scrofa xref: Reactome:REACT_102834 ! Metabolism of carbohydrates, Mus musculus xref: Reactome:REACT_103806 ! Metabolism of carbohydrates, Mycobacterium tuberculosis xref: Reactome:REACT_104502 ! Metabolism of carbohydrates, Gallus gallus xref: Reactome:REACT_105321 ! Metabolism of carbohydrates, Escherichia coli xref: Reactome:REACT_106046 ! Metabolism of carbohydrates, Drosophila melanogaster xref: Reactome:REACT_107409 ! Metabolism of carbohydrates, Caenorhabditis elegans xref: Reactome:REACT_28218 ! Metabolism of carbohydrates, Xenopus tropicalis xref: Reactome:REACT_32291 ! Metabolism of carbohydrates, Staphylococcus aureus N315 xref: Reactome:REACT_33141 ! Metabolism of carbohydrates, Taeniopygia guttata xref: Reactome:REACT_33953 ! Metabolism of carbohydrates, Rattus norvegicus xref: Reactome:REACT_34800 ! Metabolism of carbohydrates, Danio rerio xref: Reactome:REACT_474 ! Metabolism of carbohydrates, Homo sapiens xref: Reactome:REACT_77669 ! Metabolism of carbohydrates, Plasmodium falciparum xref: Reactome:REACT_81945 ! Metabolism of carbohydrates, Schizosaccharomyces pombe xref: Reactome:REACT_83038 ! Metabolism of carbohydrates, Arabidopsis thaliana xref: Reactome:REACT_83329 ! Metabolism of carbohydrates, Saccharomyces cerevisiae xref: Reactome:REACT_88330 ! Metabolism of carbohydrates, Bos taurus xref: Reactome:REACT_88558 ! Metabolism of carbohydrates, Canis familiaris xref: Reactome:REACT_96375 ! Metabolism of carbohydrates, Dictyostelium discoideum xref: Reactome:REACT_98394 ! Metabolism of carbohydrates, Oryza sativa xref: Wikipedia:Carbohydrate_metabolism is_a: GO:0008150 ! biological_process [Term] id: GO:0006091 name: generation of precursor metabolites and energy namespace: biological_process def: "The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances." [GOC:jl] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "energy pathways" BROAD [] synonym: "intermediary metabolism" RELATED [GOC:mah] synonym: "metabolic energy generation" RELATED [] is_a: GO:0008150 ! biological_process [Term] id: GO:0006260 name: DNA replication namespace: biological_process alt_id: GO:0055133 def: "The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA." [GOC:mah] comment: See also the biological process terms 'DNA-dependent DNA replication ; GO:0006261' and 'RNA-dependent DNA replication ; GO:0006278'. subset: goslim_pir subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok xref: Reactome:REACT_100559 ! Activation of ATR in response to replication stress, Mus musculus xref: Reactome:REACT_101280 ! Activation of claspin, Xenopus tropicalis xref: Reactome:REACT_101497 ! Activation of claspin, Bos taurus xref: Reactome:REACT_102679 ! Activation of ATR in response to replication stress, Gallus gallus xref: Reactome:REACT_103614 ! Stalling of DNA replication fork and RPA binding, Taeniopygia guttata xref: Reactome:REACT_104547 ! Recruitment and activation of Chk1, Gallus gallus xref: Reactome:REACT_105292 ! Activation of ATR in response to replication stress, Xenopus tropicalis xref: Reactome:REACT_105467 ! Loading of claspin onto DNA during replication origin firing, Danio rerio xref: Reactome:REACT_105835 ! Stalling of DNA replication fork and RPA binding, Gallus gallus xref: Reactome:REACT_106018 ! Recruitment of Rad17-RFC complex to DNA, Gallus gallus xref: Reactome:REACT_106104 ! Binding of ATR-ATRIP to the RPA-ssDNA complex, Bos taurus xref: Reactome:REACT_106382 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Drosophila melanogaster xref: Reactome:REACT_106434 ! Activation of claspin, Canis familiaris xref: Reactome:REACT_106732 ! Recruitment and activation of Chk1, Canis familiaris xref: Reactome:REACT_107075 ! Activation of ATR in response to replication stress, Danio rerio xref: Reactome:REACT_107423 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Caenorhabditis elegans xref: Reactome:REACT_108461 ! Recruitment and activation of Chk1, Bos taurus xref: Reactome:REACT_108634 ! Loading of claspin onto DNA during replication origin firing, Mus musculus xref: Reactome:REACT_108739 ! Binding of ATR-ATRIP to the RPA-ssDNA complex, Xenopus tropicalis xref: Reactome:REACT_108768 ! Activation of ATR in response to replication stress, Bos taurus xref: Reactome:REACT_108929 ! Activation of ATR in response to replication stress, Drosophila melanogaster xref: Reactome:REACT_109137 ! Stalling of DNA replication fork and RPA binding, Rattus norvegicus xref: Reactome:REACT_29423 ! Activation of ATR in response to replication stress, Schizosaccharomyces pombe xref: Reactome:REACT_29444 ! Binding of ATR-ATRIP to the RPA-ssDNA complex, Taeniopygia guttata xref: Reactome:REACT_29691 ! Activation of ATR in response to replication stress, Rattus norvegicus xref: Reactome:REACT_29764 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Taeniopygia guttata xref: Reactome:REACT_30149 ! Activation of claspin, Rattus norvegicus xref: Reactome:REACT_31024 ! Recruitment of Rad17-RFC complex to DNA, Xenopus tropicalis xref: Reactome:REACT_31919 ! Loading of claspin onto DNA during replication origin firing, Rattus norvegicus xref: Reactome:REACT_32546 ! Recruitment of Rad17-RFC complex to DNA, Mus musculus xref: Reactome:REACT_32932 ! Recruitment and activation of Chk1, Taeniopygia guttata xref: Reactome:REACT_33874 ! Recruitment and activation of Chk1, Xenopus tropicalis xref: Reactome:REACT_50018 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Rattus norvegicus xref: Reactome:REACT_53588 ! Loading of claspin onto DNA during replication origin firing, Canis familiaris xref: Reactome:REACT_6729 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Homo sapiens xref: Reactome:REACT_6738 ! Loading of claspin onto DNA during replication origin firing, Homo sapiens xref: Reactome:REACT_6750 ! Activation of claspin, Homo sapiens xref: Reactome:REACT_6769 ! Activation of ATR in response to replication stress, Homo sapiens xref: Reactome:REACT_6798 ! Recruitment of Rad17-RFC complex to DNA, Homo sapiens xref: Reactome:REACT_6869 ! Recruitment and activation of Chk1, Homo sapiens xref: Reactome:REACT_6936 ! Stalling of DNA replication fork and RPA binding, Homo sapiens xref: Reactome:REACT_6939 ! Binding of ATR-ATRIP to the RPA-ssDNA complex, Homo sapiens xref: Reactome:REACT_77532 ! Stalling of DNA replication fork and RPA binding, Canis familiaris xref: Reactome:REACT_79188 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Canis familiaris xref: Reactome:REACT_79450 ! Activation of ATR in response to replication stress, Dictyostelium discoideum xref: Reactome:REACT_80432 ! Loading of claspin onto DNA during replication origin firing, Taeniopygia guttata xref: Reactome:REACT_80571 ! Activation of claspin, Mus musculus xref: Reactome:REACT_80896 ! Recruitment and activation of Chk1, Sus scrofa xref: Reactome:REACT_80988 ! Loading of claspin onto DNA during replication origin firing, Bos taurus xref: Reactome:REACT_81803 ! Recruitment of Rad17-RFC complex to DNA, Canis familiaris xref: Reactome:REACT_83095 ! Recruitment of Rad17-RFC complex to DNA, Danio rerio xref: Reactome:REACT_84829 ! Binding of ATR-ATRIP to the RPA-ssDNA complex, Danio rerio xref: Reactome:REACT_85266 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Dictyostelium discoideum xref: Reactome:REACT_85561 ! Binding of ATR-ATRIP to the RPA-ssDNA complex, Rattus norvegicus xref: Reactome:REACT_86410 ! Stalling of DNA replication fork and RPA binding, Mus musculus xref: Reactome:REACT_86739 ! Recruitment and activation of Chk1, Rattus norvegicus xref: Reactome:REACT_87233 ! Binding of ATR-ATRIP to the RPA-ssDNA complex, Canis familiaris xref: Reactome:REACT_87449 ! Recruitment of Rad17-RFC complex to DNA, Rattus norvegicus xref: Reactome:REACT_87590 ! Recruitment of Rad17-RFC complex to DNA, Bos taurus xref: Reactome:REACT_88085 ! Binding of ATR-ATRIP to the RPA-ssDNA complex, Gallus gallus xref: Reactome:REACT_88384 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Schizosaccharomyces pombe xref: Reactome:REACT_88529 ! Activation of claspin, Gallus gallus xref: Reactome:REACT_89355 ! Activation of claspin, Danio rerio xref: Reactome:REACT_89439 ! Activation of ATR in response to replication stress, Sus scrofa xref: Reactome:REACT_89725 ! Loading of claspin onto DNA during replication origin firing, Drosophila melanogaster xref: Reactome:REACT_90512 ! Stalling of DNA replication fork and RPA binding, Bos taurus xref: Reactome:REACT_90809 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Danio rerio xref: Reactome:REACT_90838 ! Recruitment of Rad17-RFC complex to DNA, Taeniopygia guttata xref: Reactome:REACT_91184 ! Recruitment and activation of Chk1, Danio rerio xref: Reactome:REACT_91302 ! Activation of ATR in response to replication stress, Canis familiaris xref: Reactome:REACT_92527 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Mus musculus xref: Reactome:REACT_92644 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Xenopus tropicalis xref: Reactome:REACT_92706 ! Stalling of DNA replication fork and RPA binding, Danio rerio xref: Reactome:REACT_94983 ! Stalling of DNA replication fork and RPA binding, Xenopus tropicalis xref: Reactome:REACT_95253 ! Activation of ATR in response to replication stress, Taeniopygia guttata xref: Reactome:REACT_95329 ! Activation of claspin, Taeniopygia guttata xref: Reactome:REACT_96115 ! Binding of ATR-ATRIP to the RPA-ssDNA complex, Mus musculus xref: Reactome:REACT_96804 ! Recruitment and activation of Chk1, Mus musculus xref: Reactome:REACT_96998 ! Recruitment of the Rad9-Hus1-Rad1 complex to DNA, Bos taurus xref: Reactome:REACT_97204 ! Loading of claspin onto DNA during replication origin firing, Gallus gallus xref: Reactome:REACT_97726 ! Activation of ATR in response to replication stress, Caenorhabditis elegans xref: Reactome:REACT_99948 ! Loading of claspin onto DNA during replication origin firing, Xenopus tropicalis xref: Wikipedia:DNA_replication relationship: has_part GO:0008150 ! biological_process is_a: GO:0008150 ! biological_process [Term] id: GO:0006281 name: DNA repair namespace: biological_process def: "The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway." [PMID:11563486] subset: goslim_pir subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok xref: Reactome:REACT_102034 ! DNA Repair, Staphylococcus aureus N315 xref: Reactome:REACT_106650 ! DNA Damage Reversal, Taeniopygia guttata xref: Reactome:REACT_107446 ! DNA Repair, Arabidopsis thaliana xref: Reactome:REACT_107692 ! DNA Damage Reversal, Gallus gallus xref: Reactome:REACT_107752 ! DNA Repair, Plasmodium falciparum xref: Reactome:REACT_108864 ! DNA Damage Reversal, Rattus norvegicus xref: Reactome:REACT_108881 ! DNA Damage Reversal, Bos taurus xref: Reactome:REACT_108903 ! DNA Repair, Xenopus tropicalis xref: Reactome:REACT_109956 ! DNA Repair, Gallus gallus xref: Reactome:REACT_127 ! DNA Damage Reversal, Homo sapiens xref: Reactome:REACT_216 ! DNA Repair, Homo sapiens xref: Reactome:REACT_29531 ! DNA Damage Reversal, Saccharomyces cerevisiae xref: Reactome:REACT_29636 ! DNA Damage Reversal, Staphylococcus aureus N315 xref: Reactome:REACT_33728 ! DNA Damage Reversal, Sus scrofa xref: Reactome:REACT_34272 ! DNA Repair, Dictyostelium discoideum xref: Reactome:REACT_78051 ! DNA Damage Reversal, Canis familiaris xref: Reactome:REACT_82907 ! DNA Repair, Oryza sativa xref: Reactome:REACT_83599 ! DNA Repair, Sus scrofa xref: Reactome:REACT_83608 ! DNA Damage Reversal, Caenorhabditis elegans xref: Reactome:REACT_83660 ! DNA Repair, Escherichia coli xref: Reactome:REACT_84835 ! DNA Damage Reversal, Dictyostelium discoideum xref: Reactome:REACT_85522 ! DNA Repair, Mus musculus xref: Reactome:REACT_86513 ! DNA Repair, Mycobacterium tuberculosis xref: Reactome:REACT_86902 ! DNA Repair, Danio rerio xref: Reactome:REACT_88201 ! DNA Repair, Drosophila melanogaster xref: Reactome:REACT_88946 ! DNA Damage Reversal, Mycobacterium tuberculosis xref: Reactome:REACT_89358 ! DNA Damage Reversal, Escherichia coli xref: Reactome:REACT_89524 ! DNA Damage Reversal, Drosophila melanogaster xref: Reactome:REACT_90385 ! DNA Repair, Canis familiaris xref: Reactome:REACT_90952 ! DNA Damage Reversal, Arabidopsis thaliana xref: Reactome:REACT_91094 ! DNA Repair, Rattus norvegicus xref: Reactome:REACT_91330 ! DNA Repair, Bos taurus xref: Reactome:REACT_91442 ! DNA Repair, Caenorhabditis elegans xref: Reactome:REACT_91576 ! DNA Damage Reversal, Oryza sativa xref: Reactome:REACT_92707 ! DNA Repair, Taeniopygia guttata xref: Reactome:REACT_93704 ! DNA Repair, Saccharomyces cerevisiae xref: Reactome:REACT_94769 ! DNA Repair, Schizosaccharomyces pombe xref: Reactome:REACT_95158 ! DNA Damage Reversal, Xenopus tropicalis xref: Reactome:REACT_96452 ! DNA Damage Reversal, Danio rerio xref: Reactome:REACT_99277 ! DNA Damage Reversal, Mus musculus xref: Wikipedia:DNA_repair is_a: GO:0008150 ! biological_process [Term] id: GO:0006310 name: DNA recombination namespace: biological_process def: "Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction." [ISBN:0198506732] subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok is_a: GO:0008150 ! biological_process [Term] id: GO:0006399 name: tRNA metabolic process namespace: biological_process def: "The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established." [ISBN:0198506732] subset: goslim_generic subset: goslim_pombe subset: gosubset_prok synonym: "tRNA metabolism" EXACT [] is_a: GO:0008150 ! biological_process [Term] id: GO:0006457 name: protein folding namespace: biological_process alt_id: GO:0007022 alt_id: GO:0007024 alt_id: GO:0007025 def: "The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure." [GOC:go_curators, GOC:rb] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "alpha-tubulin folding" NARROW [GOC:mah] synonym: "beta-tubulin folding" NARROW [GOC:mah] synonym: "chaperone activity" RELATED [] synonym: "chaperonin ATPase activity" RELATED [] synonym: "chaperonin-mediated tubulin folding" NARROW [GOC:mah] synonym: "co-chaperone activity" RELATED [] synonym: "co-chaperonin activity" RELATED [] synonym: "glycoprotein-specific chaperone activity" RELATED [] synonym: "non-chaperonin molecular chaperone ATPase activity" RELATED [] synonym: "protein complex assembly, multichaperone pathway" RELATED [] xref: Reactome:REACT_100411 ! Chaperonin-mediated protein folding, Arabidopsis thaliana xref: Reactome:REACT_104912 ! Chaperonin-mediated protein folding, Caenorhabditis elegans xref: Reactome:REACT_105663 ! Chaperonin-mediated protein folding, Rattus norvegicus xref: Reactome:REACT_106009 ! Chaperonin-mediated protein folding, Canis familiaris xref: Reactome:REACT_106427 ! Chaperonin-mediated protein folding, Mus musculus xref: Reactome:REACT_106894 ! Formation of tubulin folding intermediates by CCT/TriC, Canis familiaris xref: Reactome:REACT_106927 ! Chaperonin-mediated protein folding, Drosophila melanogaster xref: Reactome:REACT_107029 ! Formation of tubulin folding intermediates by CCT/TriC, Drosophila melanogaster xref: Reactome:REACT_108248 ! Chaperonin-mediated protein folding, Gallus gallus xref: Reactome:REACT_109411 ! Formation of tubulin folding intermediates by CCT/TriC, Bos taurus xref: Reactome:REACT_110417 ! Formation of tubulin folding intermediates by CCT/TriC, Rattus norvegicus xref: Reactome:REACT_16956 ! Formation of tubulin folding intermediates by CCT/TriC, Homo sapiens xref: Reactome:REACT_17001 ! Formation of tubulin folding intermediates by CCT/TriC, Mus musculus xref: Reactome:REACT_17004 ! Chaperonin-mediated protein folding, Homo sapiens xref: Reactome:REACT_17056 ! Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding, Bos taurus xref: Reactome:REACT_23878 ! N-glycan trimming in the ER and Calnexin/Calreticulin cycle, Homo sapiens xref: Reactome:REACT_30906 ! Chaperonin-mediated protein folding, Oryza sativa xref: Reactome:REACT_32155 ! Chaperonin-mediated protein folding, Saccharomyces cerevisiae xref: Reactome:REACT_32255 ! Chaperonin-mediated protein folding, Schizosaccharomyces pombe xref: Reactome:REACT_33395 ! Formation of tubulin folding intermediates by CCT/TriC, Mus musculus xref: Reactome:REACT_77627 ! Chaperonin-mediated protein folding, Plasmodium falciparum xref: Reactome:REACT_77963 ! Formation of tubulin folding intermediates by CCT/TriC, Saccharomyces cerevisiae xref: Reactome:REACT_78530 ! Formation of tubulin folding intermediates by CCT/TriC, Gallus gallus xref: Reactome:REACT_81155 ! Formation of tubulin folding intermediates by CCT/TriC, Caenorhabditis elegans xref: Reactome:REACT_83906 ! Chaperonin-mediated protein folding, Dictyostelium discoideum xref: Reactome:REACT_85492 ! Formation of tubulin folding intermediates by CCT/TriC, Sus scrofa xref: Reactome:REACT_85496 ! Formation of tubulin folding intermediates by CCT/TriC, Plasmodium falciparum xref: Reactome:REACT_86318 ! Formation of tubulin folding intermediates by CCT/TriC, Arabidopsis thaliana xref: Reactome:REACT_91676 ! Formation of tubulin folding intermediates by CCT/TriC, Schizosaccharomyces pombe xref: Reactome:REACT_92785 ! Formation of tubulin folding intermediates by CCT/TriC, Dictyostelium discoideum xref: Reactome:REACT_92961 ! Chaperonin-mediated protein folding, Xenopus tropicalis xref: Reactome:REACT_92981 ! Chaperonin-mediated protein folding, Taeniopygia guttata xref: Reactome:REACT_94123 ! Formation of tubulin folding intermediates by CCT/TriC, Taeniopygia guttata xref: Reactome:REACT_94443 ! Formation of tubulin folding intermediates by CCT/TriC, Danio rerio xref: Reactome:REACT_94772 ! Chaperonin-mediated protein folding, Sus scrofa xref: Reactome:REACT_96773 ! Chaperonin-mediated protein folding, Danio rerio xref: Reactome:REACT_97016 ! Chaperonin-mediated protein folding, Bos taurus xref: Reactome:REACT_97220 ! Formation of tubulin folding intermediates by CCT/TriC, Xenopus tropicalis xref: Reactome:REACT_98132 ! Formation of tubulin folding intermediates by CCT/TriC, Oryza sativa xref: Wikipedia:Protein_folding is_a: GO:0008150 ! biological_process [Term] id: GO:0006461 name: protein complex assembly namespace: biological_process def: "The aggregation, arrangement and bonding together of a set of components to form a protein complex." [GOC:ai] subset: goslim_generic subset: goslim_pombe subset: gosubset_prok synonym: "chaperone activity" RELATED [] synonym: "protein complex formation" EXACT [] is_a: GO:0008150 ! biological_process relationship: part_of GO:0008150 ! biological_process [Term] id: GO:0006486 name: protein glycosylation namespace: biological_process def: "A protein modification process that results in the addition of a sugar unit to a protein amino acid, e.g. the addition of glycan chains to proteins." [GOC:curators] subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "protein amino acid glycosylation" EXACT [GOC:bf] relationship: part_of GO:0008150 ! biological_process is_a: GO:0005975 ! carbohydrate metabolic process [Term] id: GO:0006520 name: cellular amino acid metabolic process namespace: biological_process alt_id: GO:0006519 def: "The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells." [CHEBI:33709, GOC:curators, ISBN:0198506732] subset: goslim_generic subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "amino acid and derivative metabolism" EXACT [GOC:curators] synonym: "amino acid metabolic process" EXACT [GOC:curators] synonym: "cellular amino acid and derivative metabolic process" EXACT [] synonym: "cellular amino acid metabolism" EXACT [] is_a: GO:0008150 ! biological_process [Term] id: GO:0006605 name: protein targeting namespace: biological_process def: "The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif." [GOC:ma] subset: goslim_generic subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "nascent polypeptide association" RELATED [] synonym: "protein sorting along secretory pathway" NARROW [] xref: Wikipedia:Protein_targeting is_a: GO:0008150 ! biological_process relationship: part_of GO:0008150 ! biological_process relationship: occurs_in GO:0005575 ! occurs in cellular_component [Term] id: GO:0006629 name: lipid metabolic process namespace: biological_process def: "The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids." [GOC:ma] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_plant subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "lipid metabolism" EXACT [] xref: Reactome:REACT_104930 ! Lipid digestion, mobilization, and transport, Drosophila melanogaster xref: Reactome:REACT_107479 ! Lipid digestion, mobilization, and transport, Xenopus tropicalis xref: Reactome:REACT_108775 ! Lipid digestion, mobilization, and transport, Canis familiaris xref: Reactome:REACT_28745 ! Lipid digestion, mobilization, and transport, Saccharomyces cerevisiae xref: Reactome:REACT_31395 ! Lipid digestion, mobilization, and transport, Sus scrofa xref: Reactome:REACT_32539 ! Lipid digestion, mobilization, and transport, Bos taurus xref: Reactome:REACT_33836 ! Lipid digestion, mobilization, and transport, Rattus norvegicus xref: Reactome:REACT_602 ! Lipid digestion, mobilization, and transport, Homo sapiens xref: Reactome:REACT_77176 ! Lipid digestion, mobilization, and transport, Danio rerio xref: Reactome:REACT_77191 ! Lipid digestion, mobilization, and transport, Arabidopsis thaliana xref: Reactome:REACT_79244 ! Lipid digestion, mobilization, and transport, Plasmodium falciparum xref: Reactome:REACT_81778 ! Lipid digestion, mobilization, and transport, Oryza sativa xref: Reactome:REACT_82512 ! Lipid digestion, mobilization, and transport, Taeniopygia guttata xref: Reactome:REACT_82723 ! Lipid digestion, mobilization, and transport, Escherichia coli xref: Reactome:REACT_90757 ! Lipid digestion, mobilization, and transport, Mus musculus xref: Reactome:REACT_94607 ! Lipid digestion, mobilization, and transport, Mycobacterium tuberculosis xref: Reactome:REACT_97906 ! Lipid digestion, mobilization, and transport, Gallus gallus xref: Reactome:REACT_98052 ! Lipid digestion, mobilization, and transport, Caenorhabditis elegans xref: Reactome:REACT_98129 ! Lipid digestion, mobilization, and transport, Schizosaccharomyces pombe xref: Reactome:REACT_99706 ! Lipid digestion, mobilization, and transport, Dictyostelium discoideum xref: Wikipedia:Lipid_metabolism is_a: GO:0008150 ! biological_process [Term] id: GO:0006766 name: vitamin metabolic process namespace: biological_process def: "The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems." [GOC:ai] subset: goslim_candida subset: goslim_pir subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "vitamin metabolism" EXACT [] xref: Reactome:REACT_101808 ! Metabolism of vitamins and cofactors, Bos taurus xref: Reactome:REACT_101968 ! Metabolism of vitamins and cofactors, Saccharomyces cerevisiae xref: Reactome:REACT_103646 ! Metabolism of vitamins and cofactors, Staphylococcus aureus N315 xref: Reactome:REACT_105907 ! Metabolism of vitamins and cofactors, Danio rerio xref: Reactome:REACT_106152 ! Metabolism of vitamins and cofactors, Xenopus tropicalis xref: Reactome:REACT_108558 ! Metabolism of vitamins and cofactors, Rattus norvegicus xref: Reactome:REACT_110948 ! Metabolism of vitamins and cofactors, Sus scrofa xref: Reactome:REACT_11193 ! Metabolism of vitamins and cofactors, Homo sapiens xref: Reactome:REACT_30091 ! Metabolism of vitamins and cofactors, Oryza sativa xref: Reactome:REACT_33738 ! Metabolism of vitamins and cofactors, Mycobacterium tuberculosis xref: Reactome:REACT_34161 ! Metabolism of vitamins and cofactors, Mus musculus xref: Reactome:REACT_78899 ! Metabolism of vitamins and cofactors, Caenorhabditis elegans xref: Reactome:REACT_81509 ! Metabolism of vitamins and cofactors, Gallus gallus xref: Reactome:REACT_82129 ! Metabolism of vitamins and cofactors, Taeniopygia guttata xref: Reactome:REACT_83508 ! Metabolism of vitamins and cofactors, Arabidopsis thaliana xref: Reactome:REACT_87513 ! Metabolism of vitamins and cofactors, Schizosaccharomyces pombe xref: Reactome:REACT_88850 ! Metabolism of vitamins and cofactors, Dictyostelium discoideum xref: Reactome:REACT_96278 ! Metabolism of vitamins and cofactors, Plasmodium falciparum xref: Reactome:REACT_96904 ! Metabolism of vitamins and cofactors, Drosophila melanogaster xref: Reactome:REACT_97734 ! Metabolism of vitamins and cofactors, Escherichia coli xref: Reactome:REACT_97893 ! Metabolism of vitamins and cofactors, Canis familiaris is_a: GO:0008150 ! biological_process [Term] id: GO:0006913 name: nucleocytoplasmic transport namespace: biological_process alt_id: GO:0000063 def: "The directed movement of molecules between the nucleus and the cytoplasm." [GOC:go_curators] subset: goslim_generic subset: goslim_pombe synonym: "nucleocytoplasmic shuttling" NARROW [] is_a: GO:0008150 ! biological_process relationship: part_of GO:0008150 ! biological_process relationship: occurs_in GO:0005575 ! occurs in cellular_component [Term] id: GO:0007005 name: mitochondrion organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components." [GOC:dph, GOC:jl, GOC:mah, GOC:sgd_curators, PMID:9786946] subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_yeast synonym: "mitochondria organization" EXACT [GOC:mah] synonym: "mitochondrion organisation" EXACT [GOC:mah] synonym: "mitochondrion organization and biogenesis" RELATED [GOC:curators] is_a: GO:0008150 ! biological_process [Term] id: GO:0007010 name: cytoskeleton organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures." [GOC:dph, GOC:jl, GOC:mah] subset: goslim_candida subset: goslim_generic subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "cytoskeletal organization and biogenesis" RELATED [GOC:mah] synonym: "cytoskeletal regulator activity" RELATED [] synonym: "cytoskeleton organisation" EXACT [GOC:curators] synonym: "cytoskeleton organization and biogenesis" RELATED [GOC:mah] is_a: GO:0008150 ! biological_process [Term] id: GO:0007031 name: peroxisome organization namespace: biological_process def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules." [GOC:mah] subset: goslim_pir subset: goslim_pombe subset: goslim_yeast synonym: "peroxisome organisation" EXACT [GOC:curators] synonym: "peroxisome organization and biogenesis" RELATED [GOC:mah] synonym: "peroxisome-assembly ATPase activity" RELATED [] is_a: GO:0008150 ! biological_process [Term] id: GO:0007033 name: vacuole organization namespace: biological_process alt_id: GO:0044086 def: "A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole." [GOC:mah] subset: goslim_pir subset: goslim_pombe subset: goslim_yeast synonym: "vacuolar assembly" NARROW [GOC:mah] synonym: "vacuole biogenesis" RELATED [GOC:mah] synonym: "vacuole organisation" EXACT [GOC:curators] synonym: "vacuole organization and biogenesis" RELATED [GOC:mah] is_a: GO:0008150 ! biological_process [Term] id: GO:0007059 name: chromosome segregation namespace: biological_process def: "The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the alignment of chromosomes at the metaphase plate, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles." [GOC:ai, GOC:mah] subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "chromosome division" EXACT [] synonym: "chromosome transmission" RELATED [] xref: Wikipedia:Chromosome_segregation is_a: GO:0008150 ! biological_process [Term] id: GO:0007126 name: meiosis namespace: biological_process def: "A cell cycle process comprising the steps by which a cell progresses through the nuclear division phase of a meiotic cell cycle, the specialized nuclear and cell division in which a single diploid cell undergoes two nuclear divisions following a single round of DNA replication in order to produce four daughter cells that contain half the number of chromosomes as the diploid cell. Meiotic division occurs during the formation of gametes from diploid organisms and at the beginning of haplophase in those organisms that alternate between diploid and haploid generations." [GOC:dph, GOC:mah, PMID:9334324] subset: goslim_pombe xref: Wikipedia:Meiosis is_a: GO:0008150 ! biological_process relationship: part_of GO:0008150 ! biological_process [Term] id: GO:0007155 name: cell adhesion namespace: biological_process def: "The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules." [GOC:hb, GOC:pf] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: gosubset_prok synonym: "cell adhesion molecule activity" RELATED [] xref: Wikipedia:Cell_adhesion is_a: GO:0008150 ! biological_process [Term] id: GO:0007163 name: establishment or maintenance of cell polarity namespace: biological_process alt_id: GO:0030012 alt_id: GO:0030467 def: "Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns." [GOC:mah] subset: goslim_pombe synonym: "establishment and/or maintenance of cell polarity" RELATED [] synonym: "establishment and/or maintenance of cell polarization" RELATED [] is_a: GO:0008150 ! biological_process [Term] id: GO:0007346 name: regulation of mitotic cell cycle namespace: biological_process def: "Any process that modulates the rate or extent of progress through the mitotic cell cycle." [GOC:dph, GOC:go_curators, GOC:tb] subset: goslim_pombe synonym: "control of mitotic cell cycle progression" EXACT [] synonym: "mitotic cell cycle control" EXACT [] synonym: "mitotic cell cycle modulation" EXACT [] synonym: "mitotic cell cycle regulation" EXACT [] synonym: "mitotic cell cycle regulator" RELATED [] synonym: "modulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of mitotic cell cycle progression" EXACT [] synonym: "regulation of progression through mitotic cell cycle" EXACT [GOC:tb, GOC:dph] is_a: GO:0008150 ! biological_process relationship: regulates GO:0008150 ! biological_process [Term] id: GO:0008150 name: biological_process namespace: biological_process alt_id: GO:0000004 alt_id: GO:0007582 def: "Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end." [GOC:go_curators, GOC:isa_complete] comment: Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. Note that when this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code ND, no data, is used to indicate this. subset: goslim_candida subset: goslim_pir subset: goslim_plant subset: goslim_yeast subset: gosubset_prok synonym: "biological process" EXACT [] synonym: "biological process unknown" NARROW [] synonym: "physiological process" EXACT [] xref: Wikipedia:Biological_process disjoint_from: GO:0005575 ! cellular_component [Term] id: GO:0016071 name: mRNA metabolic process namespace: biological_process def: "The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes." [ISBN:0198506732] subset: goslim_pombe subset: gosubset_prok synonym: "mRNA metabolism" EXACT [] xref: Reactome:REACT_100536 ! Metabolism of mRNA, Dictyostelium discoideum xref: Reactome:REACT_107604 ! Metabolism of mRNA, Danio rerio xref: Reactome:REACT_108700 ! Metabolism of mRNA, Rattus norvegicus xref: Reactome:REACT_109292 ! Metabolism of mRNA, Drosophila melanogaster xref: Reactome:REACT_109673 ! Metabolism of mRNA, Canis familiaris xref: Reactome:REACT_109919 ! Metabolism of mRNA, Gallus gallus xref: Reactome:REACT_20605 ! Metabolism of mRNA, Homo sapiens xref: Reactome:REACT_28293 ! Metabolism of mRNA, Sus scrofa xref: Reactome:REACT_29287 ! Metabolism of mRNA, Xenopus tropicalis xref: Reactome:REACT_31547 ! Metabolism of mRNA, Plasmodium falciparum xref: Reactome:REACT_32511 ! Metabolism of mRNA, Arabidopsis thaliana xref: Reactome:REACT_33798 ! Metabolism of mRNA, Bos taurus xref: Reactome:REACT_33846 ! Metabolism of mRNA, Mus musculus xref: Reactome:REACT_34551 ! Metabolism of mRNA, Oryza sativa xref: Reactome:REACT_78090 ! Metabolism of mRNA, Caenorhabditis elegans xref: Reactome:REACT_84825 ! Metabolism of mRNA, Taeniopygia guttata xref: Reactome:REACT_87161 ! Metabolism of mRNA, Schizosaccharomyces pombe xref: Reactome:REACT_98319 ! Metabolism of mRNA, Saccharomyces cerevisiae is_a: GO:0008150 ! biological_process [Term] id: GO:0016192 name: vesicle-mediated transport namespace: biological_process alt_id: GO:0006899 def: "A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane." [GOC:ai, GOC:mah, ISBN:08789310662000] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: gosubset_prok synonym: "nonselective vesicle transport" NARROW [] synonym: "protein sorting along secretory pathway" RELATED [] synonym: "vesicle trafficking" RELATED [] synonym: "vesicle transport" EXACT [] synonym: "vesicular transport" EXACT [GOC:mah] is_a: GO:0008150 ! biological_process relationship: part_of GO:0008150 ! biological_process [Term] id: GO:0016568 name: chromatin modification namespace: biological_process def: "The alteration of DNA or protein in chromatin, which may result in changing the chromatin structure." [GOC:mah] subset: goslim_pombe is_a: GO:0051276 ! chromosome organization [Term] id: GO:0023052 name: signaling namespace: biological_process alt_id: GO:0023046 def: "The entirety of a process in which information is transmitted. This process begins with an active signal and ends when a cellular response has been triggered." [GOC:mtg_signal, GOC:mtg_signaling_feb11, GOC:signaling] comment: Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. subset: goslim_pombe subset: goslim_yeast synonym: "signaling process" EXACT [] synonym: "signalling" EXACT [] synonym: "signalling process" RELATED [GOC:mah] is_a: GO:0008150 ! biological_process creation_date: 2010-02-16T09:30:50Z [Term] id: GO:0030163 name: protein catabolic process namespace: biological_process def: "The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds." [GOC:mah] comment: This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children. subset: goslim_candida subset: goslim_pombe subset: gosubset_prok synonym: "pheromone catabolic process" RELATED [] synonym: "pheromone catabolism" RELATED [] synonym: "protein breakdown" EXACT [] synonym: "protein catabolism" EXACT [] synonym: "protein degradation" EXACT [] xref: Wikipedia:Protein_catabolism is_a: GO:0008150 ! biological_process [Term] id: GO:0030437 name: ascospore formation namespace: biological_process alt_id: GO:0007151 def: "The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota)." [GOC:mah, PMID:16339736] subset: goslim_pombe synonym: "ascospore biosynthesis" EXACT [] synonym: "spore formation" BROAD [] synonym: "sporulation" BROAD [] relationship: part_of GO:0008150 ! biological_process is_a: GO:0008150 ! biological_process [Term] id: GO:0042254 name: ribosome biogenesis namespace: biological_process alt_id: GO:0007046 def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis." [GOC:ma] subset: goslim_candida subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: gosubset_prok synonym: "ribosomal chaperone activity" RELATED [] synonym: "ribosome biogenesis and assembly" EXACT [] xref: Wikipedia:Ribosome_biogenesis is_a: GO:0008150 ! biological_process [Term] id: GO:0051186 name: cofactor metabolic process namespace: biological_process def: "The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate." [GOC:ai] subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "cofactor metabolism" EXACT [] is_a: GO:0008150 ! biological_process [Term] id: GO:0051276 name: chromosome organization namespace: biological_process alt_id: GO:0007001 alt_id: GO:0051277 def: "A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information." [GOC:ai, GOC:dph, GOC:jl, GOC:mah] subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: gosubset_prok synonym: "chromosome organisation" EXACT [] synonym: "chromosome organization and biogenesis" RELATED [GOC:mah] synonym: "maintenance of genome integrity" RELATED [] synonym: "nuclear genome maintenance" RELATED [] is_a: GO:0008150 ! biological_process [Term] id: GO:0051604 name: protein maturation namespace: biological_process def: "Any process leading to the attainment of the full functional capacity of a protein." [GOC:ai] subset: goslim_generic subset: goslim_pir subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok is_a: GO:0008150 ! biological_process relationship: part_of GO:0008150 ! biological_process [Term] id: GO:0055085 name: transmembrane transport namespace: biological_process def: "The process in which a solute is transported from one side of a membrane to the other." [GOC:dph, GOC:jid] subset: goslim_generic subset: goslim_pombe subset: goslim_yeast xref: Reactome:REACT_100480 ! SLC-mediated transmembrane transport, Taeniopygia guttata xref: Reactome:REACT_101577 ! SLC-mediated transmembrane transport, Caenorhabditis elegans xref: Reactome:REACT_101877 ! SLC-mediated transmembrane transport, Escherichia coli xref: Reactome:REACT_102348 ! Transmembrane transport of small molecules, Staphylococcus aureus N315 xref: Reactome:REACT_102897 ! Transmembrane transport of small molecules, Caenorhabditis elegans xref: Reactome:REACT_102974 ! SLC-mediated transmembrane transport, Canis familiaris xref: Reactome:REACT_104555 ! SLC-mediated transmembrane transport, Xenopus tropicalis xref: Reactome:REACT_108243 ! SLC-mediated transmembrane transport, Staphylococcus aureus N315 xref: Reactome:REACT_109832 ! Transmembrane transport of small molecules, Plasmodium falciparum xref: Reactome:REACT_110770 ! ABC-family proteins mediated transport, Mus musculus xref: Reactome:REACT_15480 ! ABC-family proteins mediated transport, Homo sapiens xref: Reactome:REACT_15518 ! Transmembrane transport of small molecules, Homo sapiens xref: Reactome:REACT_19118 ! SLC-mediated transmembrane transport, Homo sapiens xref: Reactome:REACT_28801 ! Transmembrane transport of small molecules, Sus scrofa xref: Reactome:REACT_29093 ! ABC-family proteins mediated transport, Taeniopygia guttata xref: Reactome:REACT_29184 ! SLC-mediated transmembrane transport, Gallus gallus xref: Reactome:REACT_29635 ! Transmembrane transport of small molecules, Canis familiaris xref: Reactome:REACT_30969 ! ABC-family proteins mediated transport, Canis familiaris xref: Reactome:REACT_32055 ! Transmembrane transport of small molecules, Saccharomyces cerevisiae xref: Reactome:REACT_32223 ! Transmembrane transport of small molecules, Rattus norvegicus xref: Reactome:REACT_32423 ! SLC-mediated transmembrane transport, Bos taurus xref: Reactome:REACT_32562 ! SLC-mediated transmembrane transport, Sus scrofa xref: Reactome:REACT_32713 ! ABC-family proteins mediated transport, Sus scrofa xref: Reactome:REACT_33571 ! SLC-mediated transmembrane transport, Danio rerio xref: Reactome:REACT_61245 ! Transmembrane transport of small molecules, Bos taurus xref: Reactome:REACT_79086 ! SLC-mediated transmembrane transport, Plasmodium falciparum xref: Reactome:REACT_79921 ! SLC-mediated transmembrane transport, Saccharomyces cerevisiae xref: Reactome:REACT_80022 ! ABC-family proteins mediated transport, Bos taurus xref: Reactome:REACT_80510 ! ABC-family proteins mediated transport, Rattus norvegicus xref: Reactome:REACT_80848 ! ABC-family proteins mediated transport, Schizosaccharomyces pombe xref: Reactome:REACT_80977 ! ABC-family proteins mediated transport, Caenorhabditis elegans xref: Reactome:REACT_81024 ! Transmembrane transport of small molecules, Oryza sativa xref: Reactome:REACT_81153 ! SLC-mediated transmembrane transport, Mus musculus xref: Reactome:REACT_82725 ! SLC-mediated transmembrane transport, Rattus norvegicus xref: Reactome:REACT_83770 ! Transmembrane transport of small molecules, Escherichia coli xref: Reactome:REACT_86135 ! ABC-family proteins mediated transport, Oryza sativa xref: Reactome:REACT_86409 ! Transmembrane transport of small molecules, Drosophila melanogaster xref: Reactome:REACT_86576 ! Transmembrane transport of small molecules, Schizosaccharomyces pombe xref: Reactome:REACT_87124 ! SLC-mediated transmembrane transport, Oryza sativa xref: Reactome:REACT_88059 ! ABC-family proteins mediated transport, Xenopus tropicalis xref: Reactome:REACT_88521 ! Transmembrane transport of small molecules, Taeniopygia guttata xref: Reactome:REACT_88894 ! Transmembrane transport of small molecules, Gallus gallus xref: Reactome:REACT_89376 ! SLC-mediated transmembrane transport, Schizosaccharomyces pombe xref: Reactome:REACT_91272 ! ABC-family proteins mediated transport, Arabidopsis thaliana xref: Reactome:REACT_91803 ! SLC-mediated transmembrane transport, Mycobacterium tuberculosis xref: Reactome:REACT_92006 ! Transmembrane transport of small molecules, Mycobacterium tuberculosis xref: Reactome:REACT_92624 ! ABC-family proteins mediated transport, Gallus gallus xref: Reactome:REACT_93747 ! Transmembrane transport of small molecules, Dictyostelium discoideum xref: Reactome:REACT_94160 ! Transmembrane transport of small molecules, Mus musculus xref: Reactome:REACT_94393 ! ABC-family proteins mediated transport, Drosophila melanogaster xref: Reactome:REACT_94944 ! ABC-family proteins mediated transport, Danio rerio xref: Reactome:REACT_94972 ! SLC-mediated transmembrane transport, Dictyostelium discoideum xref: Reactome:REACT_96636 ! SLC-mediated transmembrane transport, Arabidopsis thaliana xref: Reactome:REACT_97365 ! Transmembrane transport of small molecules, Arabidopsis thaliana xref: Reactome:REACT_97867 ! ABC-family proteins mediated transport, Saccharomyces cerevisiae xref: Reactome:REACT_98509 ! Transmembrane transport of small molecules, Xenopus tropicalis xref: Reactome:REACT_98716 ! SLC-mediated transmembrane transport, Drosophila melanogaster xref: Reactome:REACT_99579 ! Transmembrane transport of small molecules, Danio rerio xref: Reactome:REACT_99829 ! ABC-family proteins mediated transport, Dictyostelium discoideum relationship: part_of GO:0008150 ! biological_process is_a: GO:0008150 ! biological_process [Term] id: GO:0055086 name: nucleobase, nucleoside and nucleotide metabolic process namespace: biological_process def: "The cellular chemical reactions and pathways involving nucleobases, nucleosides and nucleotides." [GOC:vw] subset: goslim_pombe subset: goslim_yeast subset: gosubset_prok synonym: "nucleobase, nucleoside and nucleotide metabolism" EXACT [] xref: Reactome:REACT_100770 ! Metabolism of nucleotides, Plasmodium falciparum xref: Reactome:REACT_105851 ! Metabolism of nucleotides, Schizosaccharomyces pombe xref: Reactome:REACT_107755 ! Metabolism of nucleotides, Mycobacterium tuberculosis xref: Reactome:REACT_107894 ! Metabolism of nucleotides, Rattus norvegicus xref: Reactome:REACT_1698 ! Metabolism of nucleotides, Homo sapiens xref: Reactome:REACT_28046 ! Metabolism of nucleotides, Drosophila melanogaster xref: Reactome:REACT_29205 ! Metabolism of nucleotides, Dictyostelium discoideum xref: Reactome:REACT_29767 ! Metabolism of nucleotides, Saccharomyces cerevisiae xref: Reactome:REACT_33967 ! Metabolism of nucleotides, Mus musculus xref: Reactome:REACT_77113 ! Metabolism of nucleotides, Taeniopygia guttata xref: Reactome:REACT_78257 ! Metabolism of nucleotides, Staphylococcus aureus N315 xref: Reactome:REACT_82673 ! Metabolism of nucleotides, Caenorhabditis elegans xref: Reactome:REACT_82902 ! Metabolism of nucleotides, Canis familiaris xref: Reactome:REACT_82978 ! Metabolism of nucleotides, Escherichia coli xref: Reactome:REACT_83845 ! Metabolism of nucleotides, Bos taurus xref: Reactome:REACT_86759 ! Metabolism of nucleotides, Oryza sativa xref: Reactome:REACT_90371 ! Metabolism of nucleotides, Sus scrofa xref: Reactome:REACT_90903 ! Metabolism of nucleotides, Gallus gallus xref: Reactome:REACT_96600 ! Metabolism of nucleotides, Danio rerio xref: Reactome:REACT_97332 ! Metabolism of nucleotides, Arabidopsis thaliana xref: Reactome:REACT_99343 ! Metabolism of nucleotides, Xenopus tropicalis is_a: GO:0008150 ! biological_process [Term] id: GO:0070647 name: protein modification by small protein conjugation or removal namespace: biological_process def: "A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein." [GOC:mah] subset: goslim_pombe subset: goslim_yeast is_a: GO:0008150 ! biological_process created_by: midori creation_date: 2009-05-11T02:54:03Z [Term] id: GO:0070882 name: cellular cell wall organization or biogenesis namespace: biological_process def: "A cellular process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall." [GOC:mah] subset: goslim_pombe subset: gosubset_prok synonym: "cell wall organization or biogenesis at cellular level" EXACT [GOC:mah] synonym: "cellular cell wall organisation or biogenesis" EXACT [GOC:mah] is_a: GO:0008150 ! biological_process created_by: midori creation_date: 2009-08-24T03:08:05Z [Term] id: GO:0071941 name: nitrogen cycle metabolic process namespace: biological_process def: "A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization." [GOC:mah, PMID:16675690, Wikipedia:Nitrogen_cycle] subset: goslim_generic subset: goslim_pombe xref: Wikipedia:Nitrogen_cycle is_a: GO:0008150 ! biological_process created_by: midori creation_date: 2010-09-30T05:21:03Z [Typedef] id: has_part name: has_part namespace: gene_ontology xref: OBO_REL:has_part is_transitive: true created_by: midori creation_date: 2009-07-30T12:00:35Z [Typedef] id: negatively_regulates name: negatively_regulates namespace: gene_ontology [Typedef] id: occurs_in name: occurs in namespace: gene_ontology xref: BFO:0000066 [Typedef] id: part_of name: part_of namespace: gene_ontology xref: OBO_REL:part_of is_transitive: true [Typedef] id: positively_regulates name: positively_regulates namespace: gene_ontology [Typedef] id: regulates name: regulates namespace: gene_ontology