!autogenerated-by:     OBO-Edit version 1.101
!saved-by:             gocvs
!date:                 Wed Mar 26 21:30:02 PST 2008
!version: $Revision: 1.433 $
!type: % OBO_REL:is_a is_a
!type: < part_of part_of
$Gene_Ontology ; GO:0003673
 %biological_process ; GO:0008150, GO:0000004, GO:0007582 ; synonym:biological process unknown ; synonym:physiological process
  <anatomical structure morphogenesis ; GO:0009653 ; synonym:embryogenesis and morphogenesis ; synonym:morphogenesis
  %behavior ; GO:0007610 ; synonym:behavioral response to stimulus ; synonym:behaviour ; synonym:behavioural response to stimulus
  %cell communication ; GO:0007154
   %cell-cell signaling ; GO:0007267 ; synonym:cell-cell signalling
   %signal transduction ; GO:0007165 ; synonym:signaling ; synonym:signalling
  %cell cycle ; GO:0007049 ; synonym:cell-division cycle
  %cell differentiation ; GO:0030154
   <cell death ; GO:0008219 ; synonym:necrosis % death ; GO:0016265
  %cell proliferation ; GO:0008283
  %cell recognition ; GO:0008037
  %cellular component organization and biogenesis ; GO:0016043 ; synonym:cell organisation and biogenesis ; synonym:cell organization and biogenesis
   %cytoplasm organization and biogenesis ; GO:0007028 ; synonym:cytoplasm organisation and biogenesis
   %organelle organization and biogenesis ; GO:0006996 ; synonym:organelle organisation and biogenesis
    %cytoskeleton organization and biogenesis ; GO:0007010 ; synonym:cytoskeletal organization and biogenesis ; synonym:cytoskeletal regulator activity ; synonym:cytoskeleton organisation and biogenesis
    %mitochondrion organization and biogenesis ; GO:0007005 ; synonym:mitochondria organization and biogenesis ; synonym:mitochondrion organisation and biogenesis
     %mitochondrial translation ; GO:0032543 ; synonym:mitochondrial protein anabolism ; synonym:mitochondrial protein biosynthesis ; synonym:mitochondrial protein formation ; synonym:mitochondrial protein synthesis ; synonym:mitochondrial protein translation % translation ; GO:0006412
    %plastid translation ; GO:0032544 ; synonym:plastid protein anabolism ; synonym:plastid protein biosynthesis ; synonym:plastid protein formation ; synonym:plastid protein synthesis ; synonym:plastid protein translation % translation ; GO:0006412
  %cellular homeostasis ; GO:0019725
  %death ; GO:0016265
   %cell death ; GO:0008219 ; synonym:necrosis < cell differentiation ; GO:0030154
  %growth ; GO:0040007 ; synonym:growth pattern
   %cell growth ; GO:0016049 ; synonym:cell expansion ; synonym:cellular growth ; synonym:growth of cell ; synonym:metabolic process resulting in cell growth ; synonym:metabolism resulting in cell growth
  %metabolic process ; GO:0008152 ; Reactome:212093 ; Reactome:221851 ; Reactome:230419 ; Reactome:238461 ; Reactome:245002 ; Reactome:249887 ; Reactome:252604 ; Reactome:255791 ; Reactome:259186 ; Reactome:262542 ; Reactome:265367 ; Reactome:268496 ; Reactome:274223 ; Reactome:280692 ; Reactome:282903 ; Reactome:286711 ; Reactome:288374 ; Reactome:289882 ; Reactome:290414 ; Reactome:291791 ; Reactome:292439 ; Reactome:293772 ; Reactome:71408 ; synonym:metabolic process resulting in cell growth ; synonym:metabolism ; synonym:metabolism resulting in cell growth
   %biosynthetic process ; GO:0009058 ; synonym:anabolism ; synonym:biosynthesis ; synonym:formation ; synonym:synthesis
    %translation ; GO:0006412, GO:0006416, GO:0006453, GO:0043037 ; synonym:protein anabolism ; synonym:protein biosynthesis ; synonym:protein formation ; synonym:protein synthesis ; synonym:protein translation % protein metabolic process ; GO:0019538
     %mitochondrial translation ; GO:0032543 ; synonym:mitochondrial protein anabolism ; synonym:mitochondrial protein biosynthesis ; synonym:mitochondrial protein formation ; synonym:mitochondrial protein synthesis ; synonym:mitochondrial protein translation % mitochondrion organization and biogenesis ; GO:0007005
     %plastid translation ; GO:0032544 ; synonym:plastid protein anabolism ; synonym:plastid protein biosynthesis ; synonym:plastid protein formation ; synonym:plastid protein synthesis ; synonym:plastid protein translation % organelle organization and biogenesis ; GO:0006996
   %catabolic process ; GO:0009056 ; synonym:breakdown ; synonym:catabolism ; synonym:degradation
   %generation of precursor metabolites and energy ; GO:0006091 ; synonym:energy pathways ; synonym:metabolic energy generation
    %respiratory electron transport chain ; GO:0022904 ; synonym:6-phosphofructokinase reduction ; synonym:dihydrobiopterin reduction ; synonym:dihydrolipoamide reduction ; synonym:dihydrolipoylprotein reduction ; synonym:dihydropteridine reduction ; synonym:electron transfer ; synonym:other pathways of electron transport ; synonym:oxidized glutathione reduction ; synonym:protein-disulfide reduction
   %primary metabolic process ; GO:0044238 ; synonym:primary metabolism
    %amino acid and derivative metabolic process ; GO:0006519 ; synonym:amino acid and derivative metabolism
    %carbohydrate metabolic process ; GO:0005975 ; Reactome:211962 ; Reactome:221727 ; Reactome:230309 ; Reactome:238347 ; Reactome:244905 ; Reactome:249798 ; Reactome:252538 ; Reactome:255716 ; Reactome:259109 ; Reactome:262468 ; Reactome:265303 ; Reactome:268427 ; Reactome:274144 ; Reactome:280617 ; Reactome:282867 ; Reactome:286632 ; Reactome:288323 ; Reactome:289858 ; Reactome:290396 ; Reactome:291760 ; Reactome:292414 ; Reactome:293735 ; Reactome:71387 ; synonym:carbohydrate metabolism
    %lipid metabolic process ; GO:0006629 ; Reactome:211949 ; Reactome:221714 ; Reactome:230304 ; Reactome:238336 ; Reactome:244894 ; Reactome:249787 ; Reactome:252529 ; Reactome:255713 ; Reactome:259099 ; Reactome:262464 ; Reactome:265294 ; Reactome:268417 ; Reactome:274140 ; Reactome:280613 ; Reactome:282852 ; Reactome:286671 ; Reactome:288319 ; Reactome:289875 ; Reactome:290413 ; Reactome:291758 ; Reactome:292446 ; Reactome:293732 ; Reactome:73923 ; synonym:lipid metabolism
    %nucleobase\, nucleoside\, nucleotide and nucleic acid metabolic process ; GO:0006139 ; synonym:nucleobase\, nucleoside\, nucleotide and nucleic acid metabolism
     %DNA metabolic process ; GO:0006259 ; synonym:DNA metabolism
     %transcription ; GO:0006350 ; Reactome:212088 ; Reactome:221846 ; Reactome:230414 ; Reactome:238456 ; Reactome:244998 ; Reactome:249880 ; Reactome:252609 ; Reactome:255785 ; Reactome:259179 ; Reactome:262535 ; Reactome:265362 ; Reactome:268499 ; Reactome:274216 ; Reactome:280685 ; Reactome:282909 ; Reactome:286705 ; Reactome:288376 ; Reactome:74159
    %protein metabolic process ; GO:0019538, GO:0006411 ; synonym:protein metabolic process and modification ; synonym:protein metabolism ; synonym:protein metabolism and modification
     %protein modification process ; GO:0006464 ; Reactome:163841 ; Reactome:212091 ; Reactome:221849 ; Reactome:230417 ; Reactome:238459 ; Reactome:245000 ; Reactome:249885 ; Reactome:252603 ; Reactome:255790 ; Reactome:259184 ; Reactome:262540 ; Reactome:268494 ; Reactome:274221 ; Reactome:280690 ; Reactome:282898 ; Reactome:286709 ; Reactome:288370 ; synonym:process resulting in protein modification ; synonym:protein tagging activity
     %translation ; GO:0006412, GO:0006416, GO:0006453, GO:0043037 ; synonym:protein anabolism ; synonym:protein biosynthesis ; synonym:protein formation ; synonym:protein synthesis ; synonym:protein translation % biosynthetic process ; GO:0009058
      %mitochondrial translation ; GO:0032543 ; synonym:mitochondrial protein anabolism ; synonym:mitochondrial protein biosynthesis ; synonym:mitochondrial protein formation ; synonym:mitochondrial protein synthesis ; synonym:mitochondrial protein translation % mitochondrion organization and biogenesis ; GO:0007005
      %plastid translation ; GO:0032544 ; synonym:plastid protein anabolism ; synonym:plastid protein biosynthesis ; synonym:plastid protein formation ; synonym:plastid protein synthesis ; synonym:plastid protein translation % organelle organization and biogenesis ; GO:0006996
   %secondary metabolic process ; GO:0019748 ; synonym:secondary metabolism
  %multicellular organismal development ; GO:0007275
   <embryonic development ; GO:0009790, GO:0009795 ; synonym:embryogenesis ; synonym:embryogenesis and morphogenesis ; synonym:embryonal development
  %obsolete biological process ; GO:0008371
  %regulation of biological process ; GO:0050789, GO:0050791 ; synonym:regulation of physiological process
   %regulation of gene expression\, epigenetic ; GO:0040029
  %reproduction ; GO:0000003, GO:0019952, GO:0050876 ; synonym:reproductive physiological process
  %response to abiotic stimulus ; GO:0009628
  %response to biotic stimulus ; GO:0009607
  %response to endogenous stimulus ; GO:0009719
  %response to external stimulus ; GO:0009605 ; synonym:response to environmental stimulus
  %response to stress ; GO:0006950
  %symbiosis\, encompassing mutualism through parasitism ; GO:0044403, GO:0043298, GO:0044404 ; synonym:host-pathogen interaction ; synonym:symbiosis ; synonym:symbiotic interaction ; synonym:symbiotic interaction between host and organism ; synonym:symbiotic interaction between organisms ; synonym:symbiotic interaction between species ; synonym:symbiotic interaction with other non-host organism
  <transport ; GO:0006810 ; synonym:small molecule transport ; synonym:solute\:solute exchange
   %ion transport ; GO:0006811
   %protein transport ; GO:0015031, GO:0015831 ; synonym:enzyme transport
  %viral reproduction ; GO:0016032 ; Reactome:162587 ; Reactome:162906 ; Reactome:168255 ; synonym:viral infection ; synonym:viral life cycle ; synonym:viral replication cycle ; synonym:virulence
 %cellular_component ; GO:0005575, GO:0008372 ; synonym:cellular component unknown
  %cell ; GO:0005623
   <cilium ; GO:0005929
   <external encapsulating structure ; GO:0030312
    %cell envelope ; GO:0030313
    %cell wall ; GO:0005618
   <intracellular ; GO:0005622 ; synonym:protoplasm
    <chromosome ; GO:0005694 ; synonym:chromatid ; synonym:interphase chromosome ; synonym:prophase chromosome % organelle ; GO:0043226
     %cytoplasmic chromosome ; GO:0000229 ; synonym:cytoplasmic interphase chromosome < cytoplasm ; GO:0005737
     %nuclear chromosome ; GO:0000228 ; synonym:nuclear interphase chromosome < nucleus ; GO:0005634
    <cytoplasm ; GO:0005737
     <cytoplasmic chromosome ; GO:0000229 ; synonym:cytoplasmic interphase chromosome % chromosome ; GO:0005694
     <cytoplasmic membrane-bounded vesicle ; GO:0016023 ; synonym:cytoplasmic membrane bounded vesicle ; synonym:cytoplasmic membrane-enclosed vesicle % organelle ; GO:0043226
     <cytosol ; GO:0005829
     <endoplasmic reticulum ; GO:0005783 ; synonym:ER % organelle ; GO:0043226
     <endosome ; GO:0005768 % organelle ; GO:0043226
     <Golgi apparatus ; GO:0005794 ; synonym:Golgi ; synonym:Golgi complex ; synonym:Golgi ribbon % organelle ; GO:0043226
     <lipid particle ; GO:0005811 ; synonym:lipid droplet
     <microtubule organizing center ; GO:0005815 ; synonym:microtubule organising centre ; synonym:MTOC < cytoskeleton ; GO:0005856
     <mitochondrion ; GO:0005739 ; synonym:mitochondria % organelle ; GO:0043226
     <peroxisome ; GO:0005777, GO:0019818 ; synonym:peroxisome vesicle % organelle ; GO:0043226
     <plastid ; GO:0009536 % organelle ; GO:0043226
     <ribosome ; GO:0005840 ; synonym:ribosomal RNA % organelle ; GO:0043226
     <vacuole ; GO:0005773 ; synonym:vacuolar carboxypeptidase Y % organelle ; GO:0043226
      %lysosome ; GO:0005764
    <cytoskeleton ; GO:0005856 % organelle ; GO:0043226
     <microtubule organizing center ; GO:0005815 ; synonym:microtubule organising centre ; synonym:MTOC < cytoplasm ; GO:0005737
    <nucleus ; GO:0005634 % organelle ; GO:0043226
     <nuclear chromosome ; GO:0000228 ; synonym:nuclear interphase chromosome % chromosome ; GO:0005694
     <nuclear envelope ; GO:0005635, GO:0005636
     <nucleolus ; GO:0005730
     <nucleoplasm ; GO:0005654
    <thylakoid ; GO:0009579 ; synonym:photosynthetic membrane % organelle ; GO:0043226
   <plasma membrane ; GO:0005886 ; synonym:bacterial inner membrane ; synonym:cell membrane ; synonym:cytoplasmic membrane ; synonym:inner endospore membrane ; synonym:juxtamembrane ; synonym:plasmalemma
  %extracellular region ; GO:0005576 ; synonym:extracellular
   <extracellular space ; GO:0005615 ; synonym:intercellular space
   <proteinaceous extracellular matrix ; GO:0005578 ; synonym:extracellular matrix (sensu Metazoa)
  %obsolete cellular component ; GO:0008370
  %organelle ; GO:0043226
   %chromosome ; GO:0005694 ; synonym:chromatid ; synonym:interphase chromosome ; synonym:prophase chromosome < intracellular ; GO:0005622
    %cytoplasmic chromosome ; GO:0000229 ; synonym:cytoplasmic interphase chromosome < cytoplasm ; GO:0005737
    %nuclear chromosome ; GO:0000228 ; synonym:nuclear interphase chromosome < nucleus ; GO:0005634
   %cytoplasmic membrane-bounded vesicle ; GO:0016023 ; synonym:cytoplasmic membrane bounded vesicle ; synonym:cytoplasmic membrane-enclosed vesicle < cytoplasm ; GO:0005737
   %cytoskeleton ; GO:0005856 < intracellular ; GO:0005622
    <microtubule organizing center ; GO:0005815 ; synonym:microtubule organising centre ; synonym:MTOC < cytoplasm ; GO:0005737
   %endoplasmic reticulum ; GO:0005783 ; synonym:ER < cytoplasm ; GO:0005737
   %endosome ; GO:0005768 < cytoplasm ; GO:0005737
   %Golgi apparatus ; GO:0005794 ; synonym:Golgi ; synonym:Golgi complex ; synonym:Golgi ribbon < cytoplasm ; GO:0005737
   %mitochondrion ; GO:0005739 ; synonym:mitochondria < cytoplasm ; GO:0005737
   %nucleus ; GO:0005634 < intracellular ; GO:0005622
    <nuclear chromosome ; GO:0000228 ; synonym:nuclear interphase chromosome % chromosome ; GO:0005694
    <nuclear envelope ; GO:0005635, GO:0005636
    <nucleolus ; GO:0005730
    <nucleoplasm ; GO:0005654
   %peroxisome ; GO:0005777, GO:0019818 ; synonym:peroxisome vesicle < cytoplasm ; GO:0005737
   %plastid ; GO:0009536 < cytoplasm ; GO:0005737
   %ribosome ; GO:0005840 ; synonym:ribosomal RNA < cytoplasm ; GO:0005737
   %thylakoid ; GO:0009579 ; synonym:photosynthetic membrane < intracellular ; GO:0005622
   %vacuole ; GO:0005773 ; synonym:vacuolar carboxypeptidase Y < cytoplasm ; GO:0005737
    %lysosome ; GO:0005764
  %protein complex ; GO:0043234
 %molecular_function ; GO:0003674, GO:0005554 ; synonym:molecular function unknown
  %antioxidant activity ; GO:0016209
  %binding ; GO:0005488 ; synonym:ligand
   %calcium ion binding ; GO:0005509 ; synonym:calcium ion storage activity
   %carbohydrate binding ; GO:0030246 ; synonym:selectin
   %chromatin binding ; GO:0003682 ; synonym:lamin/chromatin binding ; synonym:microtubule/chromatin interaction ; synonym:nuclear membrane vesicle binding to chromatin
   %lead ion binding ; GO:0032791
   %lipid binding ; GO:0008289
   %nucleic acid binding ; GO:0003676
    %DNA binding ; GO:0003677 ; synonym:microtubule/chromatin interaction ; synonym:plasmid binding
     %transcription factor activity ; GO:0003700, GO:0000130 % transcription regulator activity ; GO:0030528
    %RNA binding ; GO:0003723
     %triplet codon-amino acid adaptor activity ; GO:0030533 ; synonym:transfer RNA ; synonym:tRNA
    %translation factor activity\, nucleic acid binding ; GO:0008135 % translation regulator activity ; GO:0045182
   %nucleotide binding ; GO:0000166
   %oxygen binding ; GO:0019825 ; Reactome:4477 ; synonym:cytochrome P450 ; synonym:cytochrome P450 activity
   %protein binding ; GO:0005515, GO:0045308 ; Reactome:6125 ; synonym:alpha-2 macroglobulin receptor-associated protein activity ; synonym:protein amino acid binding ; synonym:protein degradation tagging activity ; synonym:protein tagging activity
    %cytoskeletal protein binding ; GO:0008092
     %actin binding ; GO:0003779 ; synonym:membrane associated actin binding
    %receptor binding ; GO:0005102 ; synonym:adrenocorticotropin ; synonym:allatostatin ; synonym:insulin ; synonym:receptor ligand ; synonym:receptor-associated protein activity
  %catalytic activity ; GO:0003824 ; synonym:enzyme activity
   %electron carrier activity ; GO:0009055 ; Reactome:20046 ; synonym:2Fe-2S electron transfer carrier ; synonym:3Fe-4S/4Fe-4S electron transfer carrier ; synonym:adrenodoxin-type ferredoxin ; synonym:amicyanin ; synonym:azurin ; synonym:bacterial-type ferredoxin ; synonym:chloroplast-type ferredoxin ; synonym:copper electron carrier ; synonym:dicluster bacterial-type ferredoxin ; synonym:electron carrier\, chlorophyll electron transport system ; synonym:electron transfer flavoprotein ; synonym:electron transfer flavoprotein\, group I ; synonym:electron transfer flavoprotein\, group II ; synonym:electron transporter activity ; synonym:high-potential iron-sulfur carrier ; synonym:iron-sulfur electron transfer carrier ; synonym:monocluster bacterial-type ferredoxin ; synonym:mononuclear iron electron carrier ; synonym:polyferredoxin ; synonym:redox-active disulfide bond electron carrier ; synonym:rubredoxin ; synonym:small blue copper electron carrier ; synonym:thioredoxin-like 2Fe-2S ferredoxin
   %hydrolase activity ; GO:0016787 ; EC:3 ; Reactome:450
    %nuclease activity ; GO:0004518 ; EC:3.1.-.-
    %peptidase activity ; GO:0008233 ; EC:3.4 ; synonym:hydrolase\, acting on peptide bonds ; synonym:peptide hydrolase activity ; synonym:protease activity
    %phosphoprotein phosphatase activity ; GO:0004721 ; EC:3.1.3.16 ; MetaCyc:3.1.3.16-RXN ; Reactome:1887 ; synonym:phosphoprotein phosphohydrolase activity ; synonym:protein phosphatase activity ; synonym:protein phosphatase-1 activity ; synonym:protein phosphatase-2A activity ; synonym:protein phosphatase-2B activity ; synonym:protein phosphatase-2C activity
   %transferase activity ; GO:0016740 ; EC:2
    %kinase activity ; GO:0016301 ; Reactome:1423 ; synonym:phosphokinase activity
     %protein kinase activity ; GO:0004672, GO:0050222 ; MetaCyc:PROTEIN-KINASE-RXN ; Reactome:4030 ; synonym:protamine kinase activity
  %chaperone regulator activity ; GO:0030188
  %enzyme regulator activity ; GO:0030234 ; synonym:enzyme modulator
  %motor activity ; GO:0003774
  %nutrient reservoir activity ; GO:0045735 ; synonym:storage protein ; synonym:storage protein of fat body (sensu Insecta) ; synonym:yolk protein
  %obsolete molecular function ; GO:0008369
  %protein tag ; GO:0031386 ; synonym:protein tagging activity ; synonym:ubiquitin
  %signal transducer activity ; GO:0004871
   %receptor activity ; GO:0004872 ; synonym:receptor guanylate cyclase activity
  %structural molecule activity ; GO:0005198
  %transcription regulator activity ; GO:0030528 ; synonym:transcriptional regulator activity
   %transcription factor activity ; GO:0003700, GO:0000130 % DNA binding ; GO:0003677
  %translation regulator activity ; GO:0045182
   %translation factor activity\, nucleic acid binding ; GO:0008135 % nucleic acid binding ; GO:0003676
  %transporter activity ; GO:0005215, GO:0005478 ; Reactome:1391 ; synonym:small-molecule carrier or transporter
   %ion channel activity ; GO:0005216
   %neurotransmitter transporter activity ; GO:0005326