Biological Process Ontology Guidelines

A biological process is a recognized series of events or molecular functions. A process is a collection of molecular events with a defined beginning and end. Mutant phenotypes often reflect disruptions in biological processes.

General Considerations

Beginning and end

Every process should have a discrete beginning and end, and these should be clearly stated in the process term definition.

Collections of processes

The biological process ontology includes terms that represent collections of processes as well as terms that represent a specific, entire process. Generally, the former will have mainly is_a children, and the latter will have part_of children that represent subprocesses. Also see "is_a or part_of" below.

is_a or part_of

To determine whether a process term should be an is a or part of child of its parent, ask: is an instance of the child process an instance of the entire parent process? That is, does the whole process, from start to finish, take place? If yes, the child is is a; but if the process is only a portion of the parent process, the child is part of.

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Miscellaneous Standard Defs

membrane fusion
The joining of the lipid bilayer membrane around X to the lipid bilayer membrane around Y.
cellular component organization
A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
cellular component biogenesis
A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
macromolecular complex assembly
The aggregation, arrangement and bonding together of a set of components to form a complex.
xxx distribution
Any process that establishes the spatial arrangement of xxx.

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Last modified on 24/09/2012